College of Medicine & Dentistry
Semagn Abate
- Doctor of Philosophy (Health)
- semagn.abate@my.jcu.edu.au
Joseph Kamara
- Senior Lecturer Disaster Health and Humanitarian Assistance
- joseph.kamara@jcu.edu.au
Eric Kalo
- Lecturer Medical Education
- eric.kalo@jcu.edu.au
Erin Waters
- JCU Associate Professor
- erin.waters@jcu.edu.au
Kannan Maharajan
- Associate Professor, Pharmacy
- kannan.maharajan@jcu.edu.au
Fahmida Begum Mina
- Doctor of Philosophy (Medical, Molecular and Veterinary Sciences)
- fahmidabegum.mina@my.jcu.edu.au
Lynsey Brown
- Adjunct Senior Lecturer
- lynsey.brown@jcu.edu.au
Ali Isin
- Adjunct Senior Research Fellow
- ali.isin@jcu.edu.au
Muideen Olaiya
- Senior Research Fellow
- muideen.olaiya@jcu.edu.au
Mila Grinblat
- Postdoctoral Research Fellow
- mila.grinblat@jcu.edu.au
Comparison of PoCT for salivary cortisol with Salimetrics ELIZA Salivary Cortisol
Salivary cortisol has always been a useful tool for measuring and monitoring stress in individuals particularly in a research setting. This tool is now very much moving into a diagnostic setting with the use of salivary and hair cortisols as a part of routine psychiatric investigation. Methodological validation is important to ensure that the methods employed in research trials are validated to a standard expected in pathology laboratories and recommended by ISO15189 and local guidelines. This project will utilise salivary cortisol samples collected for two ongoing research trials to validate the Salimetrics Salivary Cortisol assay and provide researchers with quality assurance around their results.
Developing culturally appropriate tools to screen for common mental health disorders in older adults aged 45 and over living in the Torres Strait. (Old ID 27232)
The aim of the study is to develop culturally appropriate mental health assessment tools for older adults (e.g. aged 45 and over) living in the Torres Strait. Data from yarning circles with Torres Strait community members and health care staff will be used to identify how mental health disorders are expressed in the Torres Strait. A Delphi process will then be used to identify appropriate tools for assessing these domains of mental ill health for use in older adults in the Torres Strait. These tools will then be piloted to determine acceptability and validated for use in the Torres Strait.
Caregiver Burden in the Torres Strait - are we asking the right questions? (Old ID 27480)
The proposed project will investigate the best way to assess carer burden in the Torres Strait. Research suggests that current approaches to assessing carer burden may not accurately capture the Indigenous perspective of caregiver wellbeing. Yarning circles will be used to investigate carer experience in the Torres Strait. Yarning circles will focus on key issues such as the experience of burden, barriers to accessing support and providing care, and the health service response to carer issues. Findings will guide the development of a culturally appropriate framework for the assessment of carer burden, and provision of supports and tailored interventions.
Testing a novel treatment for diabetes-associated ischemic foot ulceration. (Old ID 24978)
5000 Australians with diabetes have a leg amputations each year. This project investigates a novel drug therapy approach to reducing the need for leg amputations within an established rodent model. The aim of the study is to assess if administration of a direct activator of adenosine-5'-monophosphate (AMP)-activated protein kinase (AMPK) will promote healing within a rat model of diabetes and limb ischaemia-associated foot ulceration.
HART Yarning Circle Training (Old ID 27254)
The aim of this grant is to provide travel assistance to members of the Healthy Ageing Research Team living in the Torres Strait attend yarning circle training in Cairns provided by Professor Yvonne Cadet-James
Effects of Galvus (Vildagliptin) on Markers of Inflammation in Diabetic Foot Ulcer: A Prospective, Randomized, Double-blind, Placebo-Controlled Pilot Study (Old ID 21121)
Interlukin-6 is an established inflammatory marker that has been shown to be increased in individuals with diabetic foot ulcers (DFU). Furthermore, DFU has been referred to as an inflammatory state. Therefore, a reduction in inflammatory markers in this high-risk population is likely to correlate with a corresponding improvement of diabetic foot ulcer healing. We aim to study in this pilot clinical trial the effect of Vildagliptin on regulation of IL-6 and its effects on diabetic foot ulcers healing.
Effective PPE waste processing using microwave pyrolysis (Old ID 28926)
This project aims to investigate the feasibility of processing the PPE waste materials using a Microwave Assisted Waste processing technology developed at James Cook University. The specific objectives of the project are: i. Identify the processing conditions (e.g. Microwave power, time) suitable to kill pathogens in the waste material ii. Investigate the presence of pathogens in the residual material or by-products iii. Understand the physical and chemical properties of the by-products to identify potential applications
Improving outcomes for patients with muscle wasting disease and liver cancer - SERTA Capacity Research Grant. (Old ID 28986)
The funding of a Research Assistant and the performance of work by the Research Assistant in connection with a program of work undertaken by the Cancer and Metabolism Group within the College of Public Health, Medicine and Veterinary Science aimed at improving outcomes for patients with muscle wasting disease and liver cancer.
Establishing the North Queensland Liver Cancer Library (Old ID 27086)
This project will develop a North Queensland Liver Cancer Library. Liver tumours and non-tumour tissues will be resected from patients and fixed and frozen. The tissues will also be dissociated and cultured in three dimensions to make tumour organoids that will be used in future in vivo experiments in mice, drug trials and biochemical assays.
Metformin for treating peripheral artery disease-related walking impairment (MERIT) (Old ID 24975)
Blockage of the lower limb arteries (peripheral artery disease; PAD) leads to severe leg pain, walking impairment, and a substantial risk of leg amputation and death. Approximately 200 million people worldwide and approximately 1 million Australians have blocked leg arteries. This problem has recognised treatment deficiencies in comparison to other common diseases, including the absence of effective medications to increase blood supply to the legs, reduce leg pain, improve walking ability and reduce the risk of major amputation. Multiple lines of evidence suggest that metformin, a cheap and safe medication, promotes formation of new vessels, improves microcirculation and muscle function, and limits pain. In preliminary studies, metformin significantly increased blood supply to the limb of a pre-clinical model of blocked leg arteries. We have also associated metformin prescription with a 4-fold reduction in the rate of major lower limb amputation in patients with blocked arteries. This placebo-controlled, randomised clinical trial will examine the efficacy of metformin in improving walking ability in patients with blocked leg arteries over 6 months. Positive findings from this trial will identify a new treatment for a problem that affects 10-20% of adults aged over 50 years.
An initial report on health and disease at Non Ban Jak
- 2020
- Fine Arts Department
- Researchers:Kate Domett
The application of long‑read sequencing in clinical settings
- 2023
- BioMed Central
- Researchers:Andrew MallettUlf Schmitz
Start Date:
01 Jan 2013
Start Date:
01 Jan 2021
Start Date:
01 Jan 2020
Start Date:
01 Jan 2015
Title:
Research Infrastructure Building Grant 'iCompute' ($41, 511- James Cook University, Co-Investigator
Start Date:
01 Jan 2016
Start Date:
01 Jan 2018
Start Date:
01 Jan 2006
End Date:
01 Jan 2008
Start Date:
01 Jan 2002
End Date:
01 Jan 2005