Projects 16
Publications 97
Awards 25

Biography

Biog:

I received my PhD from the University of Wales Aberystwyth (UK) in 2008 and immediately joined the JCU Vascular Biology Unit as a junior post-doctoral scientist. I was appointed to the position of Senior Scientist (Academic B) within the Vascular Biology Unit in 2011. I secured a competitive Advance Queensland Fellowship in 2017, coinciding with my promotion to Senior Research Fellow (Academic C). I was the interim honours program coordinator for the College of Medicine and Dentistry (2018) and was invited to my current position of Associate Dean Research for the College of Medicine and Dentistry in 2019. I provide strategic leadership at the College, Division and University level, whilst maintaining a highly active research portfolio.

Research:

My research focuses on Peripheral Artery Disease (PAD), a common, but neglected condition involving blockage, or weakening of the arteries outside the heart, which affects up to one quarter of older adults. PAD can manifest in a number of ways depending on the location of the disease. For example, blockages in the lower limb arteries can significantly impair walking performance and may lead to amputation. Similarly, blockages in the arteries supplying the brain significantly increase the risk of experiencing stroke. I work with teams of medical doctors and scientists to improve our understanding of PAD biology and improve patient care by:

  • Using molecular and bioinformatic approaches to identify markers associated with stroke diagnosis and outcome.
  • Identifying novel blood-based markers to diagnose, or predict risk of suffering PAD-associated events (e.g. heart attack, or requirement for surgery).
  • Testing novel medications and lifestyle interventions for PAD - most recently through the delivery of randomised controlled trials as lead analyst;
  • Identifying barriers to care in underserved populations, particularly for those in regional areas.

My work is supported by funding from a range of bodies including the QLD Government, the NHRMC, MRFF, the Emergency Medical Foundation and Philanthropic donations.

Student Supervision:

Student supervision is one of the aspects of my job that I most enjoy and I have been privileged to work with some talented students since joining JCU. To date, I have supervised 7 PhD students, one MSc student and 8 honours students to successful completion, and was awarded the JCU 'Advisory Panel Member of the Year Award' in 2022.

I currently co-supervise 2 PhD students, and am always happy to hear from any research curious candidates at any level. Students with aligning interests are encouraged to contact me with a copy of their CV and a brief outline of their research aspirations.

Other Academic Activities:

Scientific committees

  • Member of the Queensland Cardiovascular Research Network Steering Committee.
  • Director/Executive Committee member for the Australian Atherosclerosis Society (2022-2024). Key responsibilities included organising the online education seminar series, and co-convening a national scientific meeting;
  • Member of the Medical Deans of Australia and New Zealand Research Commitee (2022-2023).

Editorial board memberships:

  • Frontiers in Cardiovascular Medicine (2022-present);
  • BMC Cardiovascular Disorders (2018-present).  Key achievement included co-editing a Special Collection 'Cerebrovascular Disorders' (senior author on accompanying editorial).
  • International Journal of Molecular Sciences (2013-2020) Key achievement included co-editing a Special Issue 'Advances in Peripheral Artery Disease').

Reviewing:

I peer-review grant submissions for bodies including Diabetes Australia, the Emergency Medical Foundation and the NHMRC. I am regularly invited to peer review submitted articles for a range of journals.

Research

Research Interests

Biomarker Discovery

Abdominal Aortic Aneurysm

Peripheral Artery Disease

Stroke

Meta-analysis

Biostatistics

Clinical trials

Projects

Teaching

Teaching Interests

Research mentoring


Research Advisor Accreditation

Advisor Type

Primary

Research Advisor Accreditation

Role

Chair; Independent Academic


Taught Modules

Activities

Associations

Awards

Employment

Output

Moxon, Joseph V.; Pretorius, Cornea; Trollope, Alexandra F.; Mittal, Parul; Klingler-Hoffmann, Manuela; Hoffmann, Peter; Golledge, Jonathan (2024) 'A systematic review and in silico analysis of studies investigating the ischaemic penumbra proteome in animal models of experimental stroke'. Journal of Cerebral Blood Flow & Metabolism, 44 (10):1709-1722. [DOI]
Journal Publication Open Access ResearchOnline@JCU
Faulder, Thomas I.; Prematunga, Kurundeniya; Moloi, Soniah B.; Faulder, Lauren E.; Jones, Rhondda; Moxon, Joseph (2024) 'Agreement of Fractional Flow Reserve Estimated by Computed Tomography With Invasively Measured Fractional Flow Reserve: A Systematic Review and Meta‐Analysis'. Journal of the American Heart Association, 13 (10). [DOI]
Journal Publication Open Access ResearchOnline@JCU
Moxon, Joseph V.; Calcino, Andrew; Kraeuter, Ann-Katrin; Phie, James; Anderson, Georgina; Standley, Glenys; Sealey, Cindy; Jones, Rhondda E.; Field, Matt A.; Golledge, Jonathan (2023) 'A case–control comparison of acute-phase peripheral blood gene expression in participants diagnosed with minor ischaemic stroke or stroke mimics'. Human Genomics, 17 . [DOI]
Journal Publication Open Access ResearchOnline@JCU
Alahakoon, Chanika; Singh, Tejas P.; Morris, Dylan; Charles, James; Fernando, Malindu; Lazzarini, Peter; Moxon, Joseph V.; Golledge, Jonathan (2023) 'Cohort Study Examining the Presentation, Distribution, and Outcomes of Peripheral Artery Disease in Aboriginal, Torres Strait Islander, and Non-Indigenous Australians'. European Journal of Vascular and Endovascular Surgery, 66 (2):237-244. [DOI]
Journal Publication ResearchOnline@JCU
Alahakoon, Chanika; Singh, Tejas P.; Galappaththy, Charith; Charles, James; Fernando, Malindu; Lazzarini, Peter; Moxon, Joseph V.; Golledge, Jonathan (2023) 'Risk Factors for Hospital Re-admission for Diabetes Related Foot Disease: A Prospective Cohort Study'. European Journal of Vascular and Endovascular Surgery, 66 (2):221-228. [DOI]
Journal Publication ResearchOnline@JCU
Moxon, Joseph V.; Calcino, Andrew; Kraeuter, Ann-Katrin; Phie, James; Anderson, Georgina; Standley, Glenys; Sealey, Cindy; Jones, Rhondda E.; Field, Matt A.; Golledge, Jonathan (2023) 'A case-control comparison of acute-phase peripheral blood gene expression in participants diagnosed with minor ischaemic stroke or stroke mimics'. Human Genomics, 17 .
Journal Publication Open Access ResearchOnline@JCU
Golledge, Jonathan; Yip, Lisan; Venn, Alkira; Leicht, Anthony S.; Jenkins, Jason S.; Fiatarone Singh, Maria A.; Reid, Christopher M.; Ademi, Zanfina; Parmenter, Belinda J.; Moxon, Joseph V.; Burton, Nicola W. (2023) 'Effect of Brief Counseling by Allied Health Professionals on Step Count of People With Peripheral Artery Disease: A Randomized Clinical Trial'. Jama Cardiology, 8 (4):394-399. [DOI]
Journal Publication ResearchOnline@JCU
Singh, Tejas P.; Moxon, Joseph V.; Gasser, T. Christian; Jenkins, Jason; Bourke, Michael; Bourke, Benard; Golledge, Jonathan (2023) 'Association between aortic peak wall stress and rupture index with abdominal aortic aneurysm–related events'. European Radiology, 33 :5698-5706. [DOI]
Journal Publication Open Access ResearchOnline@JCU
Alahakoon, Chanika; Fernando, Malindu; Galappaththy, Charith; Lazzarini, Peter; Moxon, Joseph V.; Jones, Rhondda; Golledge, Jonathan (2023) 'Repeatability, completion time, and predictive ability of four diabetes-related foot ulcer classification systems'. Journal of Diabetes Science and Technology, 17 (1):35-41. [DOI]
Journal Publication ResearchOnline@JCU
Singh, Tejas P.; Moxon, Joseph V.; Gasser, T. Christian; Dalman, Ronald L.; Bourke, Michael; Bourke, Bernie; Tomee, Stephanie M.; Dawson, Joseph; Golledge, Jonathan; TEDY investigators (2022) 'Effect of Telmisartan on the Peak Wall Stress and Peak Wall Rupture Index of Small Abdominal Aortic Aneurysms: An Exploratory Analysis of the TEDY Trial'. European Journal of Vascular and Endovascular Surgery, 64 (4):396-404. [DOI]
Journal Publication ResearchOnline@JCU
Marie, Riana; Journault, Audrey-Ann; Cernik, Rebecca; Welch, Paul; Lupien, Sonia; McDermott, Brett; Moxon, Joseph V.; Sarnyai, Zoltan (2022) 'A Cross-Sectional Study Investigating Canadian and Australian Adolescents' Perceived Experiences of COVID-19: Gender Differences and Mental Health Implications'. International Journal of Environmental Research and Public Health, 19 (7). [DOI]
Journal Publication Open Access ResearchOnline@JCU
Thomas Manapurathe, Diana; Moxon, Joseph Vaughan; Krishna, Smriti Murali; Quigley, Frank; Bourke, Michael; Bourke, Bernard; Jones, Rhondda E.; Golledge, Jonathan (2022) 'Cohort Study Examining the Association of Optimal Blood Pressure Control at Entry With Infrarenal Abdominal Aortic Aneurysm Growth'. Frontiers in Cardiovascular Medicine, 9 . [DOI]
Journal Publication Open Access ResearchOnline@JCU
Moxon, Joseph V.; Kraeuter, Ann; Phie, James; Juliano, Sheryl; Anderson, Georgina; Standley, Glenys; Sealey, Cindy; White, Richard P.; Golledge, Jonathan (2022) 'Serum angiopoietin-1 concentration does not distinguish patients with ischaemic stroke from those presenting to hospital with ischaemic stroke mimics'. BMC Cardiovascular Disorders, 22 . [DOI]
Journal Publication Open Access ResearchOnline@JCU
Phie, James; Thanigaimani, Shivshankar; Huynh, Pacific; Anbalagan, Raghuveeran; Moran, Corey S.; Kinobe, Robert; Moxon, Joseph; Field, Matt A.; Krishna, Smriti M.; Golledge, Jonathan (2022) 'Colchicine Does Not Reduce Abdominal Aortic Aneurysm Growth in a Mouse Model'. Cardiovascular Therapeutics, 2022 . [DOI]
Journal Publication Open Access ResearchOnline@JCU
Matthews, Evan; Moxon, Joseph; Singh, Tejas; Thanigaimani, Shiv; Jones, Rhondda; Gasser, Thomas; Fitridge, Robert; Lindeman, Jan; Dalman, Ronald; Golledge, Jonathan (2022) 'Athero-occlusive disease appears to be associated with slower abdominal aortic aneurysm growth: an exploratory analysis of the TEDY trial'. European Journal of Vascular and Endovascular Surgery, 63 (4):632-640. [DOI]
Journal Publication ResearchOnline@JCU
Phie, J.; Krishna, S.M.; Kinobe, R.; Moxon, J.V.; Andrade-Lima, A.; Morton, S.K.; Lazzaroni, S.M.; Huynh, P.; Golledge, J. (2021) 'Effects of quercetin on exercise performance, physical activity and blood supply in a novel model of sustained hind-limb ischaemia'. BJS Open, 5 (1). [DOI]
Journal Publication Open Access ResearchOnline@JCU
Thanigaimani, Shivshankar; Phie, James; Krishna, Smriti; Moxon, Joseph; Golledge, Jonathan (2021) 'Effect of disease modifying anti-rheumatic drugs on major cardiovascular events: a meta-analysis of randomized controlled trials'. Scientific Reports, 11 (1). [DOI]
Journal Publication Open Access ResearchOnline@JCU
Zhen, Lijiin; Moxon, Joseph; Gorton, Susan; Hook, Daniel (2021) 'Can I breastfeed my baby with Down syndrome? A scoping review'. Journal of Paediatrics and Child Health, 57 (12):1866-1880. [DOI]
Journal Publication ResearchOnline@JCU
Thanigaimani, Shiv; Phie, James; Sharma, Chinmay; Wong, Shannon; Ibrahim, Muhammad; Huynh, Pacific; Moxon, Joseph; Jones, Rhondda; Golledge, Jonathan (2021) 'Network meta‐analysis comparing the outcomes of treatments for intermittent claudication tested in randomized controlled trials'. Journal of the American Heart Association, 10 (9). [DOI]
Journal Publication Open Access ResearchOnline@JCU
Thanigaimani, Shivshankar; Singh, Tejas P.; Unosson, Jon; Phie, James; Moxon, Joseph; Wanhainen, Anders; Golledge, Jonathan (2021) 'Association between metformin prescription and abdominal aortic aneurysm growth and clinical events: a systematic review and meta-analysis'. European Journal of Vascular and Endovascular Surgery, 62 (5):747-756. [DOI]
Journal Publication ResearchOnline@JCU
Singh, Tejas P.; Moxon, Joseph V.; Gasser, T. Christian; Golledge, Jonathan (2021) 'Systematic review and meta-analysis of peak wall stress and peak wall rupture index in ruptured and asymptomatic intact abdominal aortic aneurysms'. Journal of the American Heart Association, 10 (8). [DOI]
Journal Publication Open Access ResearchOnline@JCU
Singh, T.P.; Moxon, J.V.; Iyer, V.; Gasser, T.C.; Jenkins, J.; Golledge, J. (2021) 'Comparison of peak wall stress and peak wall rupture index in ruptured and asymptomatic intact abdominal aortic aneurysms'. British Journal of Surgery, 108 (6):652-658. [DOI]
Journal Publication ResearchOnline@JCU
Matthews, Evan O.; Pinchbeck, Jenna; Elmore, Kylie; Jones, Rhondda; Moxon, Joseph V.; Golledge, Jonathan (2021) 'The reproducibility of measuring maximum abdominal aortic aneurysm diameter from ultrasound images'. The Ultrasound Journal, 13 . [DOI]
Journal Publication Open Access ResearchOnline@JCU
Smith, Samuel L.; Norman, Richard; Moxon, Joseph V.; Velu, Ramesh; Quigley, Frank; Golledge, Jonathan (2021) 'Outcomes and costs of open and endovascular revascularisation for chronic limb ischaemia in an Australian cohort'. Heart, Lung and Circulation, 30 (10):1552-1561. [DOI]
Journal Publication ResearchOnline@JCU
Nastasi, Domenico R.; Norman, Richard; Moxon, Joseph V.; Quigley, Frank; Velu, Ramesh; Jenkins, Jason; Golledge, Jonathan (2021) 'The potential benefits and costs of an intensified approach to low density lipoprotein cholesterol lowering in people with abdominal aortic aneurysm'. European Journal of Vascular and Endovascular Surgery, 62 (4):643-650. [DOI]
Journal Publication ResearchOnline@JCU
Nastasi, Domenico R.; Moxon, Joseph V.; Norman, Richard; Trollope, Alex F.; Rowbotham, Sophie; Quigley, Frank; Jenkins, Jason; Golledge, Jonathan (2021) 'The cost-effectiveness of intensive low-density lipoprotein cholesterol lowering in people with peripheral artery disease'. Journal of Vascular Surgery, 73 (4):1396-1403.e3. [DOI]
Journal Publication ResearchOnline@JCU
Singh, Tejas P.; Moxon, Joseph V.; Meehan, Michael T.; Jones, Rhondda; Cadet-James, Yvonne; Golledge, Jonathan (2021) 'Major amputation rates and outcomes for Aboriginal and Torres Strait Islander and non-Indigenous people in North Queensland Australia between 2000 and 2015'. BMC Endocrine Disorders, 21 (1). [DOI]
Journal Publication Open Access ResearchOnline@JCU
Golledge, Jonathan; Drovandi, Aaron; Velu, Ramesh; Moxon, Joseph (2021) 'Cohort study examining the relationship between remoteness and requirement for surgery to treat peripheral artery disease at a tertiary hospital in North Queensland'. Australian Journal of Rural Health, 29 (4):512-520. [DOI]
Journal Publication ResearchOnline@JCU
Golledge, J.; Moxon, J. V.; Singh, T. P.; Bown, M. J.; Mani, K.; Wanhainen, A. (2020) 'Lack of an effective drug therapy for abdominal aortic aneurysm'. Journal of Internal Medicine, 288 (1):6-22. [DOI]
Journal Publication ResearchOnline@JCU
Nsengiyumva, Vianne; Krishna, Smriti M.; Moran, Corey S.; Moxon, Joseph V.; Morton, Susan K.; Clarke, Michael; Seto, Sai-Wang; Golledge, Jonathan (2020) 'Vitamin D deficiency promotes large rupture-prone abdominal aortic aneurysms and cholecalciferol supplementation limits progression of aneurysms in a mouse model'. Clinical Science, 134 (18):2521-2534. [DOI]
Journal Publication Open Access ResearchOnline@JCU
Moxon, Joseph V.; Rowbotham, Sophie E.; Pinchbeck, Jenna L.; Lazzaroni, Sharon M.; Morton, Susan K.; Moran, Corey S.; Quigley, Frank; Jenkins, Jason S.; Reid, Christopher M.; Cavaye, Doug; Jaeggi, Rene; Golledge, Jonathan (2020) 'A randomised controlled trial assessing the effects of peri-operative fenofibrate administration on abdominal aortic aneurysm pathology: outcomes from the FAME trial'. European Journal of Vascular and Endovascular Surgery, 60 (3):452-460. [DOI]
Journal Publication ResearchOnline@JCU
Golledge, Jonathan; Pinchbeck, Jenna; Rowbotham, Sophie; Yip, Lisan; Jenkins, Jason; Quigley, Frank; Moxon, Joseph V. (2020) 'Health-related quality of life amongst people diagnosed with abdominal aortic aneurysm and peripheral artery disease and the effect of fenofibrate'. Scientific Reports, 10 . [DOI]
Journal Publication Open Access ResearchOnline@JCU
Golledge, Jonathan; Drovandi, Aaron; Velu, Ramesh; Quigley, Frank; Moxon, Joseph (2020) 'Survival following abdominal aortic aneurysm repair in North Queensland is not associated with remoteness of place of residence'. PLoS ONE, 15 (11). [DOI]
Journal Publication Open Access ResearchOnline@JCU
Golledge, Jonathan; Moxon, Joseph V.; Rowbotham, Sophie; Pinchbeck, Jenna; Quigley, Frank; Jenkins, Jason (2020) 'High ankle brachial index predicts high risk of cardiovascular events amongst people with peripheral artery disease'. PLoS ONE, 15 (11). [DOI]
Journal Publication Open Access ResearchOnline@JCU
Alahakoon, C.; Fernando, M.; Galappaththy, C.; Matthews, E.O.; Lazzarini, P.; Moxon, J.V.; Golledge, J. (2020) 'Meta-analyses of randomized controlled trials reporting the effect of home foot temperature monitoring, patient education or offloading footwear on the incidence of diabetes-related foot ulcers'. Diabetic Medicine, 37 (8):1266-1279. [DOI]
Journal Publication ResearchOnline@JCU
Golledge, Jonathan; Pinchbeck, Jenna; Tomee, Stephanie M.; Rowbotham, Sophie E.; Singh, Tejas P.; Moxon, Joseph V.; Jenkins, Jason S.; Lindeman, Jan H.; Dalman, Ronald L.; McDonnell, Lori; Fitridge, Robert; Morris, Dylan R.; TEDY Investigators (2020) 'Efficacy of Telmisartan to slow growth of small abdominal aortic aneurysms: a randomized clinical trial'. Jama Cardiology, 5 (12):1374-1381. [DOI]
Journal Publication ResearchOnline@JCU
Singh, Tejas P.; Wong, Shannon A.; Moxon, Joseph V.; Gasser, T. Christian; Golledge, Jonathan (2019) 'Systematic review and meta-analysis of the association between intraluminal thrombus volume and abdominal aortic aneurysm rupture'. Journal of Vascular Surgery, 70 (6):2065-2073. [DOI]
Journal Publication ResearchOnline@JCU
Smith, Samuel L.; Matthews, Evan O.; Moxon, Joseph V.; Golledge, Jonathan (2019) 'A systematic review and meta-analysis of risk factors for and incidence of 30-day readmission after revascularization for peripheral artery disease'. Journal of Vascular Surgery, 70 (3):996-1006. [DOI]
Journal Publication ResearchOnline@JCU
Golledge, J.; Singh, T. P.; Alahakoon, C.; Pinchbeck, J.; Yip, L.; Moxon, J. V.; Morris, D. R. (2019) 'Meta-analysis of clinical trials examining the benefit of structured home exercise programmes in patients with peripheral artery disease'. British Journal of Surgery, 106 :319-331. [DOI]
Journal Publication ResearchOnline@JCU
Golledge, Jonathan; Morris, Dylan R.; Pinchbeck, Jenna; Rowbotham, Sophie; Jenkins, Jason; Bourke, Michael; Bourke, Bernard; Norman, Paul E.; Jones, Rhonda; Moxon, Joseph V. (2019) 'Metformin prescription is associated with reduced risk of surgical repair and rupture-related mortality in patients with abdominal aortic aneurysm'. European Journal of Vascular and Endovascular Surgery, 57 (1):94-101. [DOI]
Journal Publication ResearchOnline@JCU
Thomas Manapurathe, Diana; Moxon, Joseph Vaughan; Krishna, Smriti Murali; Rowbotham, Sophie; Quigley, Frank; Jenkins, Jason; Bourke, Michael; Bourke, Bernard; Jones, Rhondda E.; Golledge, Jonathan (2019) 'Cohort study examining the association between blood pressure and cardiovascular events in patients with peripheral artery disease'. Journal of the American Heart Association, 8 . [DOI]
Journal Publication Open Access ResearchOnline@JCU
Moxon, Joseph V.; Trollope, Alex F.; Dewdney, Brittany; de Hollander, Catherine; Nastasi, Domenico R.; Maguire, Jane M.; Golledge, Jonathan (2019) 'The effect of angiopoietin-1 upregulation on the outcome of acute ischaemic stroke in rodent models: a meta-analysis'. Journal of Cerebral Blood Flow & Metabolism, 39 (12):2343-2354. [DOI]
Journal Publication Open Access ResearchOnline@JCU
Singh, Tejas P.; Skallina, Tristan; Nour, Daniel; Murali, Aarya; Morrison, Sean; Moxon, Joseph V.; Golledge, Jonathan (2018) 'A meta-analysis of the efficacy of allopurinol in reducing the incidence of myocardial infarction following coronary artery bypass grafting'. BMC Cardiovascular Disorders, 18 . [DOI]
Journal Publication Open Access ResearchOnline@JCU
Morris, Dylan R.; Skalina, Tristan A.; Singh, Tejas P.; Moxon, Joseph V.; Golledge, Jonathan (2018) 'Association of computed tomographic leg muscle characteristics with lower limb and cardiovascular events in patients with peripheral artery disease'. Journal of the American Heart Association, 7 (20). [DOI]
Journal Publication Open Access ResearchOnline@JCU
Nastasi, Domenico R.; Smith, Justin R.; Moxon, Joseph V.; Trollope, Alex; Golledge, Jonathan (2018) 'Prescription of pharmacotherapy and the incidence of stroke in patients with symptoms of peripheral artery disease'. Stroke, 49 (12). [DOI]
Journal Publication Open Access ResearchOnline@JCU
Golledge, Jonathan; Maarij, Khyber; Moxon, Joseph V.; Beard, Jonathan D.; Girold, Sebastien; Wrang, Hans; Morris, Dylan R. (2018) 'Systematic review and meta-analysis of clinical trials examining the benefit of exercise programmes using Nordic walking in patients with peripheral artery disease'. European Journal of Vascular and Endovascular Surgery, 56 (4):534-543. [DOI]
Journal Publication ResearchOnline@JCU
Phie, James; Moxon, Joseph V.; Krishna, Smriti M.; Kinobe, Robert; Morton, Susan K.; Golledge, Jonathan (2018) 'A diet enriched with tree nuts reduces severity of atherosclerosis but not abdominal aneurysm in angiotensin II-infused apolipoprotein E deficient mice'. Atherosclerosis, 277 :28-33. [DOI]
Journal Publication ResearchOnline@JCU
Dewdney, Brittany Alexandra; Trollope, Alex; Moxon, Joseph; Thomas Manapurathe, Diana; Biros, Erik; Golledge, Jonathan (2018) 'Circulating microRNAs as biomarkers for acute ischemic stroke: a systematic review'. Journal of Stroke and Cerebrovascular Diseases, 27 (3):522-530. [DOI]
Journal Publication ResearchOnline@JCU
Moxon, Joseph V.; Ng, Eugene; Lazzaroni, Sharon M.; Boult, Margaret; Velu, Ramesh; Fitridge, Robert A.; Golledge, Jonathan (2018) 'Circulating biomarkers are not associated wtih endoleaks after endovascular repair of abdominal aortic aneurysms'. Journal of Vascular Surgery, 67 (3):770-777. [DOI]
Journal Publication Open Access ResearchOnline@JCU
Singh, Tejas P.; Moxon, Joseph; Healy, Genevieve N.; Cadet-James, Yvonne; Golledge, Jonathan (2018) 'Presentation and outcomes of indigenous Australians with peripheral artery disease'. BMC Cardiovascular Disorders, 18 (94). [DOI]
Journal Publication Open Access ResearchOnline@JCU
Krishna, Smriti M.; Moxon, Joseph V.; Jose, Roby J.; Sahebkar, Amir; Hatamipour, Mahdi; Liu, Dawie; Golledge, Jonathan (2018) 'Anionic nanoliposomes reduced atherosclerosis progression in Low Density Lipoprotein Receptor (LDLR) deficient mice fed a high fat diet'. Journal of Cellular Physiology, 233 (10):6951-6964. [DOI]
Journal Publication ResearchOnline@JCU
Pinchbeck, Jenna L.; Moxon, Joseph V.; Rowbotham, Sophie E.; Bourke, Michael; Lazzaroni, Sharon; Morton, Susan K.; Matthews, Evan O.; Hendy, Kerolos; Jones, Rhondda E.; Bourke, Bernie; Jaeggi, Rene; Favot, Danella; Quigley, Frank; Jenkins, Jason S.; Reid, Christopher M.; Velu, Ramesh; Golledge, Jonathan (2018) 'A randomized placebo-controlled trial assessing the effect of 24 weeks fenofibrate therapy on circulating markers of abdominal aortic aneurysm: outcomes from the FAME-2 trial'. Journal of the American Heart Association, 7 (19). [DOI]
Journal Publication Open Access ResearchOnline@JCU
Golledge, J.; Moxon, J.V.; Rowbotham, S.; Pinchbeck, J.; Yip, L.; Velu, R.; Quigley, F.; Jenkins, J.; Morris, D. (2018) 'Risk of major amputation in patients with intermittent claudication undergoing early revascularization'. British Journal of Surgery, 105 (6):699-708. [DOI]
Journal Publication Open Access ResearchOnline@JCU
Krishna, Smriti Murali; Seto, Sai Wang; Jose, Roby; Li, Jiaze; Moxon, Joseph; Clancy, Paula; Crossman, David J.; Norman, Paul; Emeto, Theophilus I.; Golledge, Jonathan (2017) 'High serum thrombospondin-1 concentration is associated with slower abdominal aortic aneurysm growth and deficiency promotes angiotensin-II induced aneurysm in mice'. Clinical Science, 131 (12):1261-1281. [DOI]
Journal Publication Open Access ResearchOnline@JCU
Rowbotham, Sophie E.; Cavaye, Doug; Jaeggi, Rene; Jenkins, Jason S.; Moran, Corey S.; Moxon, Joseph V.; Pinchbeck, Jenna L.; Quigley, Frank; Reid, Christopher M.; Golledge, Jonathan (2017) 'Fenofibrate in the management of AbdoMinal aortic anEurysm (FAME): study protocol for a randomised controlled trial'. Trials, 18 (1):1-8. [DOI]
Journal Publication Open Access ResearchOnline@JCU
Morris, D.R.; Singh, T.P.; Moxon, J.V.; Smith, A.; Stewart, F.; Jones, R.E.; Golledge, J. (2017) 'Assessment and validation of a novel angiographic scoring system for peripheral artery disease'. British Journal of Surgery, 104 :544-554. [DOI]
Journal Publication ResearchOnline@JCU
Moran, Corey S.; Biros, Erik; Krishna, Smriti M.; Wang, Yutang; Tikellis, Chris; Moxon, Joseph V.; Cooper, Mark E.; Norman, Paul E.; Burrell, Louise M.; Thomas, Merlin C.; Golledge, Jonathan (2017) 'Resveratrol inhibits growth of experimental abdominal aortic aneurysm associated with upregulation of angiotensin-converting enzyme 2'. Arteriosclerosis Thrombosis and Vascular Biology, 37 (11):2195-2218. [DOI]
Journal Publication ResearchOnline@JCU
Matthews, E.O.; Rowbotham, S.E.; Moxon, J.V.; Jones, R.E.; Vega de Ceniga, M.; Golledge, J. (2017) 'Meta-analysis of the association between peripheral artery disease and growth of abdominal aortic aneurysms'. British Journal of Surgery, 104 (13):1765-1774. [DOI]
Journal Publication ResearchOnline@JCU
Phie, James; Krishna, Smriti M.; Moxon, Joseph V.; Omer, Safraz M.; Kinobe, Robert; Golledge, Jonathan (2017) 'Flavonols reduce aortic atherosclerosis lesion area in apolipoprotein E deficient mice: a systematic review and meta-analysis'. PLoS ONE, 12 (7):1-13. [DOI]
Journal Publication Open Access ResearchOnline@JCU
Moxon, Joseph V.; Jones, Rhondda E.; Wong, Gerard; Weir, Jacquelyn M.; Mellett, Natalie A.; Kingwell, Bronwyn A.; Meikle, Peter J.; Golledge, Jonathan (2017) 'Baseline serum phosphatidylcholine plasmalogen concentrations are inversely associated with incident myocardial infarction in patients with mixed peripheral artery disease presentations'. Atherosclerosis, 263 :301-308. [DOI]
Journal Publication ResearchOnline@JCU
Singh, T. P.; Morris, D. R.; Smith, S.; Moxon, J. V.; Golledge, J. (2017) 'A systematic review and meta-analysis of the association between C-reactive protein and major cardiovascular events in patients with peripheral artery disease'. European Journal of Vascular and Endovascular Surgery, 54 (2):220-233. [DOI]
Journal Publication ResearchOnline@JCU
Golledge, J.; Moxon, J.; Pinchbeck, J.; Anderson, G.; Rowbotham, S.; Jenkins, J.; Bourke, M.; Bourke, B.; Dear, A.; Buckenham, T.; Jones, R.; Norman, P.E. (2017) 'Metformin prescription is associated with reduced abdominal aortic aneurysm growth in three cohorts'. British Journal of Surgery, 104 (11):1486-1493. [DOI]
Journal Publication ResearchOnline@JCU
Thomas Manapurathe, Diana; Krishna, Smriti Murali; Dewdney, Brittany; Moxon, Joseph Vaughan; Biros, Erik; Golledge, Jonathan (2017) 'Effect of blood pressure lowering medication on peripheral artery disease: a meta-analysis of randomised controlled trials'. PLoS ONE, 12 (6):1-12. [DOI]
Journal Publication Open Access ResearchOnline@JCU
Rowbotham, Sophie E.; Pinchbeck, Jenna L.; Anderson, Georgina; Bourke, Bernie; Bourke, Michael; Gasser, T. Christian; Jaeggi, Rene; Jenkins, Jason S.; Moran, Corey S.; Morton, Susan K.; Reid, Christopher M.; Velu, Ramesh; Yip, Lisan; Moxon, Joseph V.; Golledge, Jonathan (2017) 'Inositol in the MAnaGemENt of abdominal aortic aneurysm (IMAGEN): study protocol for a randomised controlled trial'. Trials, 18 . [DOI]
Journal Publication Open Access ResearchOnline@JCU
Moxon, Joseph V.; Jones, Rhondda E.; Norman, Paul E.; Clancy, Paula; Flicker, Leon; Almeida, Osvaldo P.; Hankey, Graeme J.; Yeap, Bu B.; Golledge, Jonathan (2016) 'Plasma ferritin concentrations are not associated with abdominal aortic aneurysm diagnosis, size or growth'. Atherosclerosis, 251 :19-24. [DOI]
Journal Publication Open Access ResearchOnline@JCU
Rowbotham, Sophie E.; Bourke, Bernie; Bourke, Michael; Jaeggi, Rene; Jenkins, Jason S.; Moxon, Joseph V.; Pinchbeck, Jenna L.; Reid, Christopher M.; Velu, Ramesh; Golledge, Jonathan (2016) 'Fenofibrate in the management of AbdoMinal aortic anEurysm (FAME)-2: the study protocol for a multi-centre, randomised, placebo-controlled trial'. International Journal of Clinical Trials, 3 (4):217-224. [DOI]
Journal Publication Open Access ResearchOnline@JCU
Morton, Susan K.; Rodríguez, Alexander J.; Morris, Dylan R.; Bhandari, Abhista P.; Moxon, Joseph V.; Golledge, Jonathan (2016) 'A systematic review and meta-analysis of circulating biomarkers associated with failure of arteriovenous fistuale for haemodialysis'. PLoS ONE, 11 (7):1-15. [DOI]
Journal Publication Open Access ResearchOnline@JCU
Zhang, Chao; van der Voort, Dustin; Shi, Hong; Zhang, Rongli; Qing, Yulan; Hiraoka, Shuichi; Takemoto, Minoru; Yokote, Koutaro; Moxon, Joseph; Norman, Paul; Rittié, Laure; Kuivaniemi, Helena; Atkins, G. Brandon; Gerson, Stanton; Shi, Guo-Ping; Golledge, Jonathan; Dong, Nianguo; Prosdocimo, Domenick; Lin, Zhiyong (2016) 'Matricellular protein CCN3 mitigates abdominal aortic aneurysm'. Journal of Clinical Investigation, 126 (4):1282-1299. [DOI]
Journal Publication Open Access ResearchOnline@JCU
Emeto, Theophilus I.; Moxon, Joseph V.; Au, Minnie; Golledge, Jonathan (2016) 'Oxidative stress and abdominal aortic aneurysm: potential treatment targets'. Clinical Science, 130 (5):301-315. [DOI]
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Mohamed Omer, Safraz; Krishna, Smriti Murali; Li, Jiaze; Moxon, Joseph Vaughan; Nsengiyumva, Vianne; Golledge, Jonathan (2016) 'The efficacy of extraembryonic stem cells in improving blood flow within animal models of lower limb ischaemia'. Heart, 102 (1):69-74. [DOI]
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Krishna, Smriti Murali; Moxon, Joseph V.; Golledge, Jonathan (2015) 'A review of the pathophysiology and potential biomarkers for peripheral artery disease'. International Journal of Molecular Sciences, 16 (5):11294-11322. [DOI]
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Golledge, J.; Moxon, J.V.; Jones, R.E.; Hankey, G.J.; Yeap, B.B.; Flicker, L.; Norman, P.E. (2015) 'Reported amount of salt added to food is associated with increased all-cause and cancer-related mortality in older men in a prospective cohort study'. Journal of Nutrition, Health and Aging, 19 (8):805-811. [DOI]
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Nsengiyumva, Vianne; Fernando, Malindu E.; Moxon, Joseph V.; Krishna, Smriti M.; Pinchbeck, Jenna; Omer, Safraz M.; Morris, Dylan R.; Jones, Rhondda E.; Moran, Corey S.; Seto, Sai W.; Golledge, Jonathan (2015) 'The association of circulating 25-hydroxyvitamin D concentration with peripheral arterial disease: a meta-analysis of observational studies'. Atherosclerosis, 243 (2):645-651. [DOI]
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Moxon, Joseph V.; Behl-Gilhotra, Ratnesh; Morton, Susan K.; Krishna, Smriti M.; Seto, Sai Wang; Biros, Erik; Nataatmadja, Maria; West, Malcolm; Walker, Phillip J.; Norman, Paul E.; Golledge, Jonathan (2015) 'Plasma low-density lipoprotein receptor-related protein 1 concentration is not associated with human abdominal aortic aneurysm presence'. European Journal of Vascular and Endovascular Surgery, 50 (4):466-473. [DOI]
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Emeto, Theophilus I.; Moxon, Joseph V.; Biros, Erik; Rush, Catherine M.; Clancy, Paula; Woodward, Lynn; Moran, Corey S.; Jose, Roby J.; Nguyen, Tan; Walker, Philip J.; Golledge, Jonathan (2014) 'Urocortin 2 is associated with abdominal aortic aneurysm and mediates anti-proliferative effects on vascular smooth muscle cells via corticotrophin releasing factor receptor 2'. Clinical Science, 126 (7):517-527. [DOI]
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Khosla, S; Morris, D.R.; Moxon, J.V.; Walker, P.J.; Gasser, T.C.; Golledge, J. (2014) 'Meta-analysis of peak wall stress in ruptured, symptomatic and intact abdominal aortic aneurysms'. British Journal of Surgery, 101 (11):1350-1357. [DOI]
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Moxon, Joseph V.; Liu, Dawei; Wong, Gerard; Weir, Jacquelyn M.; Behl-Gilhotra, Ratnesh; Bradshaw, Barbara; Kingwell, Bronwyn A.; Meikle, Peter J.; Golledge, Jonathan (2014) 'Comparison of the serum lipidome in patients with abdominal aortic aneurysm and peripheral artery disease'. Circulation: Cardiovascular Genetics, 7 (1):71-79. [DOI]
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Moxon, Joseph V.; Liu, Dawei; Moran, Corey S.; Crossman, David J.; Krishna, Smriti M.; Yonglitthipagon, Ponlapat; Emeto, Theophilus I.; Morris, Dylan R.; Padula, Matthew P.; Mulvenna, Jason P.; Rush, Catherine M.; Golledge, Jonathan (2014) 'Proteomic and genomic analyses suggest the association of Apolipoprotein C1 with abdominal aortic aneurysm'. Proteomics Clinical Applications, 8 (10):762-772. [DOI]
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Wang, Yutang; Krishna, Smriti M.; Moxon, Joseph; Nguyen Dinh, Tam; Jose, Roby J.; Yu, Hongyou; Golledge, Jonathan (2014) 'Influence of apolipoprotein E, age and aortic site on calcium phosphate induced abdominal aortic aneurysm in mice'. Atherosclerosis, 235 (1):204-212. [DOI]
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Golledge, Jonathan; Quigley, Frank; Velu, Ramesh; Walker, Phillip J.; Moxon, Joseph V. (2014) 'Association of impaired fasting glucose, diabetes and their management with the presentation and outcome of peripheral artery disease: a cohort study'. Cardiovascular Diabetology, 13 :1-9. [DOI]
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Morris, Dylan R.; Rodriguez, Alexander J.; Moxon, Joseph V.; Cunningham, Margaret A.; McDermott, Mary M.; Myers, Jonathan; Leeper, Nicholas J.; Jones, Rhondda E.; Golledge, Jonathan (2014) 'Association of lower extremity performance with cardiovascular and all-cause mortality in patients with peripheral artery disease: a systematic review and meta-analysis'. Journal of the American Heart Association, 3 . [DOI]
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Moran, Corey S.; Jose, Roby J.; Moxon, Joseph V.; Roomberg, Alicia; Norman, Paul E.; Rush, Catherine; Korner, Heinrich; Golledge, Jonathan (2013) 'Everolimus limits aortic aneurysm in the apolipoprotein E-deficient mouse by downregulating C-C chemokine receptor 2 positive monocytes'. Arteriosclerosis, Thrombosis and Vascular Biology, 33 (4):814-821. [DOI]
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Golledge, Jonathan; Cronin, Oliver; Iyer, Vikram; Bradshaw, Barbara; Moxon, Joseph V.; Cunningham, Maggie (2013) 'Body mass index is inversely associated with mortality in patients with peripheral vascular disease'. Atherosclerosis, 229 (2):549-555. [DOI]
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Morris, Dylan R.; Moxon, Joseph V.; Biros, Erik; Krishna, Smriti M.; Golledge, Jonathan (2012) 'Meta-analysis of the association between transforming growth factor-beta polymorphisms and complications of coronary heart disease'. PLoS ONE, 7 (5):1-8. [DOI]
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Lacourse, E. James; Perally, Samirah; Morphew, Russell M.; Moxon, Joseph V.; Prescott, Mark; Dowling, David J.; O'Neill, Sandra M.; Kipar, Anja; Hetzel, Udo; Hoey, Elizabeth; Zafra, Rafael; Buffoni, Leandro; Arévalo, José Pérez; Brophy, Peter M. (2012) 'The sigma class glutathione transferase from the liver fluke Fasciola hepatica'. PLoS Neglected Tropical Disease, 6 (5):1-14. [DOI]
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Krishna, Smriti M.; Seto, Sai Wang; Moxon, Joseph V.; Rush, Catherine; Walker, Phillip J.; Norman, Paul E.; Golledge, Jonathan (2012) 'Fenofibrate increases high-density lipoprotein and sphingosine 1 phosphate concentrations limiting abdominal aortic aneurysm progression in a mouse model'. American Journal of Pathology, 181 (2):706-718. [DOI]
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Emeto, Theophilus I.; Moxon, Joseph V.; Rush, Catherine; Woodward, Lynn; Golledge, Jonathan (2011) 'Relevance of urocortins to cardiovascular disease'. Journal of Molecular and Cellular Cardiology, 51 (3):299-307. [DOI]
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Trollope, Alexandra; Moxon, Joseph V.; Moran, Corey S.; Golledge, Jonathan (2011) 'Animal models of abdominal aortic aneurysm and their role in furthering management of human disease'. Cardiovascular Research, 20 (2):114-123. [DOI]
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Biros, Erik; Norman, Paul E.; Jones, Gregory T.; van Rij, Andre M.; Yu, Grace; Moxon, Joseph V.; Blankensteijn, Jan D.; van Sterkenburg, Steven M.; Morris, Dylan; Baas, Annette F.; Golledge, Jonathan (2011) 'Meta-analysis of the association between single nucleotide polymorphisms in TGF-β receptor genes and abdominal aortic aneurysm'. Atherosclerosis, 219 (1):218-223. [DOI]
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Moxon, Joseph V.; Padula, Matthew P.; Clancy, Paula; Emeto, Theophilus I.; Herbert, Ben R.; Norman, Paul E.; Golledge, Jonathan (2011) 'Proteomic analysis of intra-arterial thrombus secretions reveals a negative association of clusterin and thrombospondin-1 with abdominal aortic aneurysm'. Atherosclerosis, 219 :432-439. [DOI]
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Moxon, J.V.; Flynn, R.J.; Golden, O.; Hamilton, J.V.; Mulcahy, G.; Brophy, P.M. (2010) 'Immune responses directed at egg proteins during experimental infection with the liver fluke Fasciola hepatica'. Parasite Immunology, 32 (2):111-124. [DOI]
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Moxon, Joseph V.; LaCourse, E. James; Wright, Hazel A.; Perally, Samirah; Prescott, Mark C.; Gillard, Jennifer L.; Barrett, John; Hamilton, Joanne V.; Brophy, Peter M. (2010) 'Proteomic analysis of embryonic Fasciola hepatica: characterization and antigenic potential of a developmentally regulated heat shock protein'. Veterinary Parasitology, 169 (1-2):62-75. [DOI]
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Moxon, Joseph V.; Parr, Adam; Emeto, Theophilus I.; Walker, Phillip; Norman, Paul E.; Golledge, Jonathan (2010) 'Diagnosis and monitoring of abdominal aortic aneurysm: current status and future prospects'. Current Problems in Cardiology, 35 (10):512-548. [DOI]
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Moxon, J.V.; Padula, M.P.; Herbert, B.R.; Golledge, J. (2009) 'Challenges, current status and future perspectives of proteomics in improving understanding, diagnosis and treatment of vascular disease'. European Journal of Vascular and Endovascular Surgery, 38 :346-355. [DOI]
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Rush, Catherine; Nyara, Moses; Moxon, Joseph V.; Trollope, Alexandra; Cullen, Bradford; Golledge, Jonathan (2009) 'Whole genome expression analysis within the angiotensin II-apolipoprotein E deficient mouse model of abdominal aortic aneurysm'. BMC Genomics, 10 (298). [DOI]
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Chemale, Gustavo; Morphew, Russell; Moxon, Joseph V.; Morassuti, Alessandra L.; LaCourse, E.James; Barrett, John; Johnston, David A.; Brophy, Peter M. (2006) 'Proteomic analysis of glutathione transferases from the liver fluke parasite, Fasciola hepatica'. Proteomics, 6 (23):6263-6273. [DOI]
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Moxon, Joseph V.; Krishna, Smriti M.; Singh, Tejas P.; Golledge, Jonathan (2020) 'Abdominal aortic aneurysm pathology and progress towards a medical therapy' In: Moxon, Joseph V., Krishna, Smriti M., Singh, Tejas P., and Golledge, Jonathan (2020) Abdominal aortic aneurysm pathology and progress towards a medical therapy. In: Fitridge, Robert, (ed.) Mechanisms of Vascular Disease: a textbook for vascular specialists. Springer, Cham, Switzerland, pp. 263-291(Eds.). Mechanisms of Vascular Disease: a textbook for vascular specialists. Cham, Switzerland : Springer. [DOI]
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