College of Medicine & Dentistry
Semagn Abate
- Doctor of Philosophy (Health)
- semagn.abate@my.jcu.edu.au
Joseph Kamara
- Senior Lecturer Disaster Health and Humanitarian Assistance
- joseph.kamara@jcu.edu.au
Eric Kalo
- Lecturer Medical Education
- eric.kalo@jcu.edu.au
Erin Waters
- JCU Associate Professor
- erin.waters@jcu.edu.au
Kannan Maharajan
- Associate Professor, Pharmacy
- kannan.maharajan@jcu.edu.au
Fahmida Begum Mina
- Doctor of Philosophy (Medical, Molecular and Veterinary Sciences)
- fahmidabegum.mina@my.jcu.edu.au
Lynsey Brown
- Adjunct Senior Lecturer
- lynsey.brown@jcu.edu.au
Ali Isin
- Adjunct Senior Research Fellow
- ali.isin@jcu.edu.au
Muideen Olaiya
- Senior Research Fellow
- muideen.olaiya@jcu.edu.au
Mila Grinblat
- Postdoctoral Research Fellow
- mila.grinblat@jcu.edu.au
Developing culturally appropriate mental health assessment tools for older adults living in the Torres Strait (Old ID 27220)
Sarah Russell
01 Jul 2021 - 31 Aug 2026
The aim of the study is to develop culturally appropriate mental health assessment tools for older adults (e.g. aged 45 and over) living in the Torres Strait. Data from yarning circles with Torres Strait community members and health care staff will be used to identify how mental health disorders are expressed in the Torres Strait. A Delphi process will then be used to identify appropriate tools for assessing these domains of mental ill health for use in older adults in the Torres Strait. These tools will then be piloted to determine acceptability and validated for use in the Torres Strait.
The KidGen National Kidney Genomics Program – improving genomic outcomes for Australian families with genetic kidney disease (Old ID 27287)
Andrew Mallett
01 Jun 2021 - 31 Dec 2026
The KidGen National Kidney Genomic Program is an Australian national and translational genomics program addressing the clinical need to urgently improve identification and diagnosis of novel monogenic rare kidney diseases. Our vision is to improve the diagnostic and clinical outcomes of Australian patients and families affected by genetic kidney disease (GKD) through personalised application of novel genomic approaches at national scale and within a multidisciplinary context. We will materially increase the genetic diagnosis rate in this space towards 70% by 2025 whilst enabling earlier and more efficient genomic diagnosis of rare kidney disorders. World-leading genomic approaches will be utilised to improve connection and capacity, including the application of advanced research and functional genomics to identify and validate novel gene variants in our extensive patient cohort. Through our established national network of multidisciplinary clinics this will inform clinical options and pathways for affected Australian families and accelerate translation and integration of genomics knowledge and technology into kidney clinical practice.
Treatment as Prevention in Correctional Facilities in Southern Africa (TasP Prisons) (Old ID 22496)
Steph Topp
01 Aug 2015 - 31 Dec 2017
Limited data from Southern Africa suggest that concentration of HIV-infected individuals and high-risk sexual behaviours in correctional facilities may be driving HIV transmission in incarcerated populations. Despite the implications of incarceration - related HIV transmission on individual and public health, little evidence exists to guide implementation of HIV prevention strategies in these settings. One such strategy, Treatment as Prevention (TasP), offers promise to: (1) prevent HIV transmission among incarcerated men having sex with men and people who use drugs; and (2) improve inmate health and tuberculosis control. In this project we will implement TasP in three correctional facilities - one in Zambia and two in South Africa - and evaluate TasP implementation as a strategy to coordinate the HIV care continuum and assure appropriate TB assessment among HIV-infected inmates.
Exploring the Long-Term Effects of Probiotic Supplementation in Premature Infants (Old ID 27031)
Donna Rudd
16 Oct 2020 - 22 Jul 2025
Probiotic supplementation is now standard care for pre-term infants in the neonatal intensive care unit (NICU); significantly reducing the risk of Necrotising Enterocolitis (NEC) and mortality. What is not known is the long-term impact of this probiotic treatment on the developing infant gut microbiome. Evidence from a previous study shows positive effects, however, two important questions remain. 1. Microbes from probiotic supplementation appear to colonize the infant gut, cause positive modulation and reduce the incidence of disease, does this effect persist over the first year of life? 2. Should the criteria for probiotic supplementation be expanded to include all infants?
Review of Tokelau's Clinical Health Services and Patient Referrals Sceme (Old ID 26397)
Michelle Redman-MacLaren
05 Dec 2018 - 30 Jun 2020
The Tokelau Government has asked for an independent review of the Tokelau Patient Referrals Scheme (TPRS) and clinical health services. In partnership with the Tokelau Government, the New Zealand Ministry of Foreign Affairs and Trade (MFAT) has engaged a Massey University-led team to do the review. Our proposal is distinguished by three features in particular: the team is Pacific-led, the review design is bottom up, participatory and solutions-focussed, and our approach is grounded in a Tokelauan world view of health and wellbeing. This approach will allow for the co-creation of knowledge, will ensure that the review is inclusive of a diversity of views, including marginalised groups, and will enable us to undertake an in-depth review which reflects the social, economic, cultural and spiritual context. Methodological innovations such as use of the Systems Assessment Tool and particpatory co-design workshops will enable us to generate robust findings combining quantitative and qualitative data.
Generation of novel peptide-MHC antibody therapies to combat seasonal and pandemic potential influenza virus (Old ID 28968)
Hillary Vanderven
27 Mar 2023 - 31 Dec 2027
Influenza pandemics have caused significant morbidity and mortality throughout history. The 1918 influenza pandemic resulted in 25-50 million deaths globally. Myrio Therapeutics is a Melbourne-based company leading the development of antibodies directed to peptide-MHC (pMHC) targets. Myrio’s competitive edge is provided by a patented Retained Display (ReD) discovery platform allowing rapid isolation of high affinity human single chain antibodies, which are readily converted into different therapeutic formats. Myrio has identified several first-in-class antibodies against highly conserved influenza virus peptides presented on common human leukocyte antigens (HLAs) for further testing in vitro and in vivo in mice.
Exploring the educational and program impact of strategies to increase high quality GP registrar supervision and training in underserved communities in north-western Queensland (Old ID 25073)
Richard Murray
01 Jul 2018 - 30 Jun 2019
This project builds on the previously funded ACRRM ERG - to develop a general practice workforce that is aligned with population health needs and optimising workforce sustainability and training in rural and remote areas. The first project identified underserved communities where GP registrar training capacity could be better targeted by strategically establishing registrar training posts in underserved communities. New training posts have been established or are in development in the underserved areas identified by the first project. This new project will evaluate these new training posts; measuring the educational impact of training in underserved areas and the impact of training posts on local communities.
Governance and accountability: the experience of Aboriginal Health Workers (Old ID 25066)
Steph Topp
01 Jul 2018 - 31 Dec 2018
This program will form a foundational component of Dr. Topp’s long term vision to develop a JCU-based health systems governance research program focussing on Australia’s remote and rural health workforce. The proposed project encompasses the first empirical study on AHW governance in Australia, leveraging collaborations with key industry stakeholders in the tropical north. Outcomes, both publications and established industry relationships, will form the basis for future competitive grant applications that extend Dr. Topp’s research expertise and presence, including by opening up new opportunities for collaborations with international colleagues working in the health system governance and accountability domain.
Classifying the Type and Severtiy of Traumatic Injury in North Queensland: A Multicentre Retrospective Study (Old ID 26830)
Hayley Letson
01 Oct 2020 - 01 Mar 2023
Queenslanders living in regional, rural and remote areas having a higher incidence of traumatic injury and are disadvantaged by prolonged prehospital times. The aim of this project is to define and describe trauma patients transported by aeromedical emergency services to and between Townsville, Cairns, Mt Isa and Mackay hospitals over a 3 - year period (2016-2018). A key objective is to conduct a comprehensive analysis of clinical interventions and therapies from point-of-injury to hospital admission, and patient outcomes to hospital discharge. This data will help inform all stakeholders on the current state of emergency trauma care in the tropics.
Clinical and economic evaluation of novel blood tests for stroke (Old ID 23159)
Joseph Moxon
01 Aug 2017 - 01 Sep 2021
This clinical study aims to test the ability for 2 novel blood borne markers to 1) diagnose stroke and 2) predict patient outcomes 90 days after stroke onset. In partnership with the Townsville Hospital, I will recruit presenting patients suffering suspected stroke and collect blood samples at presentation and after 24 hours as part of their usual care. Blood will be analysed for circulating concentrations of the novel markers which will be statistically compared to current gold standards in stroke assessment. Patients will be followed up at 3 months to assess disability, and perform economic analyses to quantify healthcare costs.
Regenerating lizard tails: A new model for investigating lymphangiogenesis
- 2003
- Researchers:Suzy Munns
Association of osteoprotegerin with human abdominal aortic aneurysm progression
- 2005
- American Heart Association
- Researchers:Jonathan Golledge
A simple plan: cnidarians and the origins of developmental mechanisms
- 2004
- Nature Publishing
- Researchers:David Miller
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