Medicine
Erin Waters
- JCU Associate Professor
- erin.waters@jcu.edu.au
Shiv Thanigaimani
- Senior Research Fellow, Peripheral Vascular Disease (PVD)
- shiv.thanigaimani@jcu.edu.au
Alkira Deren
- Clinical Research Officer
- alkira.venn@jcu.edu.au
Michael Robinson
- JCU Lecturer
- michael.robinson@jcu.edu.au
Nalita Turner
- Research Officer
- nalita.turner@jcu.edu.au
Bunmi Malau-Aduli
- JCU Professor
- bunmi.malauaduli@jcu.edu.au
Jenna Graffini
- Research Project Manager
- jenna.graffini@jcu.edu.au
Mel Muscat
- Adjunct Research Fellow
- melody.muscat@jcu.edu.au
Yvonne Hornby-Turner
- Adjunct Research Fellow
- yvonne.hornbyturner@jcu.edu.au
Geoffrey Dobson
- Professor
- geoffrey.dobson@jcu.edu.au
Exploring the educational and program impact of strategies to increase high quality GP registrar supervision and training in underserved communities in north-western Queensland (Old ID 25073)
Richard Murray
01 Jul 2018 - 30 Jun 2019
This project builds on the previously funded ACRRM ERG - to develop a general practice workforce that is aligned with population health needs and optimising workforce sustainability and training in rural and remote areas. The first project identified underserved communities where GP registrar training capacity could be better targeted by strategically establishing registrar training posts in underserved communities. New training posts have been established or are in development in the underserved areas identified by the first project. This new project will evaluate these new training posts; measuring the educational impact of training in underserved areas and the impact of training posts on local communities.
Classifying the Type and Severtiy of Traumatic Injury in North Queensland: A Multicentre Retrospective Study (Old ID 26830)
Hayley Letson
01 Oct 2020 - 01 Mar 2023
Queenslanders living in regional, rural and remote areas having a higher incidence of traumatic injury and are disadvantaged by prolonged prehospital times. The aim of this project is to define and describe trauma patients transported by aeromedical emergency services to and between Townsville, Cairns, Mt Isa and Mackay hospitals over a 3 - year period (2016-2018). A key objective is to conduct a comprehensive analysis of clinical interventions and therapies from point-of-injury to hospital admission, and patient outcomes to hospital discharge. This data will help inform all stakeholders on the current state of emergency trauma care in the tropics.
Clinical and economic evaluation of novel blood tests for stroke (Old ID 23159)
Joseph Moxon
01 Aug 2017 - 01 Sep 2021
This clinical study aims to test the ability for 2 novel blood borne markers to 1) diagnose stroke and 2) predict patient outcomes 90 days after stroke onset. In partnership with the Townsville Hospital, I will recruit presenting patients suffering suspected stroke and collect blood samples at presentation and after 24 hours as part of their usual care. Blood will be analysed for circulating concentrations of the novel markers which will be statistically compared to current gold standards in stroke assessment. Patients will be followed up at 3 months to assess disability, and perform economic analyses to quantify healthcare costs.
TRIAGE: A disease agnostic computational and modelling platform to accelerate variant classification (Old ID 27849)
Andrew Mallett
01 Jun 2022 - 31 May 2027
This proposal develops a disease-agnostic, high throughput and scalable functional genomics platform integrating computational variant prediction and disease modelling to increase the diagnostic rate of unresolved cases and accelerate development of experimental therapeutics. We implement a novel unsupervised, disease agnostic, genome-wide computational analysis method called TRIAGE which provides predictions at single base resolution across the human genome, revealing the likelihood of a variant being pathogenic. No other methods compare with TRIAGE in identifying genes associated with developmental process and cell differentiation where variants in these loci are associated with congenital disease and multi-organ syndromes. Our team of experts across Australia’s research and clinical sectors bring skills in bioinformatics, statistical genetics, clinical genetics, and disease modelling. In Aim 1 we incorporate tested genome-wide metrics, such as TRIAGE, to build open access machine learning methods that enhance variant prediction in clinical data. Aim 2 implements TRIAGE in Australian Genomic cohorts and registries to identify prioritised and novel candidates for disease modelling and develop strategies and guidelines for advancing TRIAGE in clinical genetic diagnostics and functional genomics networks. Aim 3 uses TRIAGE to prioritise variants for disease modelling across a multi-institutional phenotyping platform. Disease modelling includes innovative genome-wide molecular phenotyping coupled with physiological assays in cell and animal models. At the completion of the grant, we aim to implement TRIAGE in standard clinical genetic analysis protocols and deliver phenotyping data to assist in classification of unresolved genetic diseases. These achievements will result in diagnoses and mechanism of disease that will directly benefit patients in obtaining medical and psychosocial support and create pathways to new therapies.
Proposed development of revised framework for operational and implementation research in health and disease control programmes. (Old ID 27222)
Karen Carlisle
26 Apr 2021 - 24 Sep 2021
Strong, responsive and resilient health systems are the critical foundation for global health security. Health systems depend on effective functioning of both people and networks in order to implement effective disease control programmes, detect and respond quickly to infectious disease threats and develop evidence-informed policy/practice. The purpose of this work is to develop a revised framework for operational and implementation research (OR/IR) in health and disease control programs. This framework can be used to develop adequate and sustainable OR/IR capacity in public health programs and create an organisational culture of policy and practice that is informed by evidence-informed decision making.
Strengthening the Quality of Dementia Care in Aboriginal and Torres Strait Islander Residential Aged Care (Old ID 27652)
Yvonne Hornby-Turner
01 Feb 2022 - 31 May 2022
Aim: Develop and field-test an audit tool for assessing the standard of dementia care in Aboriginal/Torres Strait Islander residential aged care (RAC), against Quality Standards and Best Practice guidelines for dementia care. Method: - Undertake scoping review on best practice dementia care; - Develop a standardised audit tool based on scoping review evidence; - Field-test tool to evaluate face and content validity and inter-rater reliability. Outcome: Best practice dementia care audit tool and accompanying manual. Significance: Groundwork for a larger funding application to Dementia Australia that will test the audit tool and inform the feasibility and acceptability of a continuous quality improvement approach for strengthening dementia care in Aboriginal/Torres Strait Islander RAC.
'Let's get active at Dialysis', an Exercise Physiology led activity program at North Ward Haemodialysis centre (Old ID 23471)
Lisa Simmons
31 Jul 2017 - 30 Jun 2019
This study will aim to answer the research question: Is exercise performed during dialysis sufficient to improve clinical outcomes of haemodialysis patients? The aim of the study is to measure the effect of progressive resistance training during dialysis on HD patients.
Low does of oral corticosteroids in the treatment of painful acute otitis externa (swimmer's ear) - A randomized controlled triple blind trial (Old ID 22836)
Ronny Gunnarsson
01 Jul 2016 - 30 Aug 2016
Otitis Externa is a frequent problem in the tropics. Pain and swelling often makes topical treatment difficult. A few practitioners use oral corticosteroids as an adjuvant therapy despite lack of evidence. This study aims to evaluate the effect of oral corticosteroids on painful otitis externa.
Effectiveness of exercise intervention on improving psychological effects in prostate cancer patients (Old ID 22378)
Lisa Simmons
20 May 2015 - 31 Dec 2017
This study aims to detemine whether implementing an exercise program for localised prostate cancer patients at the Townsville Cancer Centre will be an effective tool in reducing the side effects of treatment and improving mental health.
Identifying the roles of online communities in rural resilience (Old ID 26434)
Karen Carlisle
01 Jan 2020 - 31 Dec 2022
The role of online communities in helping rural people to overcome isolation and service inaccessibility, and in identifying service priorities, is the study focus. We will apply social media data analytics to study seven diverse examples of online communities, to inform what rural people discuss, where, when and in different online communities and to identify the impact of online communities in addressing rural resilience. Findings will inform workshops with online hosts to develop and test a 'best practice toolkit' to inform future online community data analy6tics. The project's outcomes will be to: extend knowledge about roles of online communities for realising rural resilience and providing data to inform service innovations.
Systematic review and meta-analysis of peak wall stress and peak wall rupture index in ruptured and asymptomatic intact abdominal aortic aneurysms
- 2021
- Wiley-Blackwell
- Researchers:Joseph MoxonJonathan Golledge
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