Projects 10
Publications 69
Awards 0

Biography

Ira Cooke is an Associate Professor in bioinformatics and co-director of the Centre for Tropical Bioinformatics and Molecular Biology. He uses a range of high throughput (big data) molecular techniques to understand the evolution, molecular biology and ecology of marine organisms.

Ira’s research uses population genomics to understand local adaptation in the marine environment by connecting recent biogeographical events with evolutionary processes on specific genes and genomic regions. One of the major goals of this work is to improve our understanding of the basic molecular biology of marine taxa (ie what genes do and how they are regulated). To further this goal Ira often works collaboratively, providing bioinformatic expertise to projects combining evo-devo, physiological and comparative genomic approaches.

Ira also develops analytical tools that facilitate research on the molecular biology of marine taxa. These tools are typically targeted at specific questions, relevant to biology-focussed projects. For example his research group developed a tool for classifying antimicrobial peptides from protein sequences (ampir) to facilitate work on coral-microbe interactions. In the past he has worked on tools to simplify working with mass-spectrometry-based proteomics data.

Ira completed his BSc (hons) at JCU in marine biology and chemistry, followed by a PhD in physics at Australian National University. He then completed a postdoc with Prof. Markus Deserno at the Max Planck institute for polymer physics in Germany where he developed a model for simulating large scale lipid self assembly. This was followed by several years in the UK working on economic and ecological models of farmland with Prof. Bill Sutherland. Ira returned to Australia in 2010 to take up a role as bioinformatician in the La Trobe University mass spectrometry facility. In 2016 he moved to James Cook University.

Research

Projects

Teaching

Taught Modules

Current JCU Research Students

Genetic assessment of Acropora kenti populations and its symbionts at Yunbenun (Magnetic Island), Australia, and its adjacent reefs
Master of Philosophy (Natural and Physical Sciences)
Effects of genetic load and its consequences on long-term persistence in small, isolated wildlife populations
Doctor of Philosophy (Natural and Physical Sciences)
Regulation of the bacterial histidyl enzymes – phosphoenolpyruvate synthetase and pyruvate, orthophosphate dikinase
Doctor of Philosophy (MHMS) (Res)
Analysis of Genomic Structural Variants in Coral Populations and their role in Gene Flow, Adaptive Evolution, and Diversification.
Doctor of Philosophy (Natural and Physical Sciences)
Testing Assisted Gene Flow to Improve Coral Heat Tolerance: An Integrated Experimental, Field, and Molecular Assessment
Doctor of Philosophy (Natural and Physical Sciences)
Unravelling genomic patterns of population structure and fitness in the Australian koala (Phascolarctos cinereus)
Doctor of Philosophy (Natural and Physical Sciences)
Host-microbial interaction during the coral Black Band Disease (BBD) progression
Doctor of Philosophy (Agriculture, Environmental and Related Studies)
Sequencing the genome of Cladocopium C15: a critical resource for investigating Cnidaria-Symbiodiniaceae specificity
Master of Philosophy (Medical, Molecular and Veterinary Sciences)
Characterization of the CpG methylation distribution and patterns in the mushroom coral Heliofungia actiniformis
Doctor of Philosophy (Medical, Molecular and Veterinary Sciences)
Population genomics of dugongs (Dugong dugon) in northern Australia
Doctor of Philosophy (Natural and Physical Sciences)
The evolution of allochronic spawning in corals
Doctor of Philosophy (Medical, Molecular and Veterinary Sciences)

Completed JCU Research Students

Improving Diagnostics and Management of Shellfish Allergy: Identifying Putative Allergens in Shellfish and Cross-Reactive Novel Allergens in Edible Insects;;
Doctor of Philosophy (Medical and Molecular Sciences)- 2024
Phylogenomics of Antipatharia (Black Corals) and their role as Reef Ecosystem Engineers
Doctor of Philosophy (Natural and Physical Sciences)- 2025
Molecular insights into a novel coral model, Heliofungia actiniformis
Doctor of Philosophy (Medical and Molecular Sciences)- 2022
Identifying antimicrobial peptides in genomes using machine learning methods
Doctor of Philosophy (Medical and Molecular Sciences)- 2022
The role of T-cadherin in regulating skeletal muscle myogenesis
Doctor of Philosophy (Medical and Molecular Sciences)- 2024
The iridescent enigma: Genome evolution and species boundaries of the blue-ringed octopus species complex (Octopodidae: Hapalochlaena)
Doctor of Philosophy (Natural and Physical Sciences)- 2021
Decoding the Genetic Response to Heat Stress in Abalone (genus Haliotis);;
Doctor of Philosophy (Natural and Physical Sciences)- 2025
The molecular bases of regeneration and the heat shock response that underlines coral bleaching
Doctor of Philosophy (Natural and Physical Sciences)- 2024
Biogeography, reproductive biology and early development in scleractinian corals
Doctor of Philosophy (Medical and Molecular Sciences)- 2022
Natural variation in heat tolerance of corals on the Great Barrier Reef
Doctor of Philosophy (Natural and Physical Sciences)- 2023
Novel targets and strategies in the treatment of liver and oral pharyngeal cancer
Master of Philosophy (Medical and Molecular Sciences)- 2021
Investigating receptors and signalling pathways of coral settlement and metamorphosis using proteomics,transcriptomics and phylogenetics;;
Doctor of Philosophy (Medical and Molecular Sciences)- 2023
Exploiting whole-genome sequencing to understand the evolution of corals and their symbionts
Doctor of Philosophy (Medical and Molecular Sciences)- 2023
Characterizing the associated bacterial community in the model Alcyoniid Lobophytum pauciflorum
Doctor of Philosophy (Medical and Molecular Sciences)- 2021

Output

Lau, Sally C.Y.; Wilson, Nerida G.; Watts, Phillip C.; Silva, Catarina N.S.; Cooke, Ira R.; Allcock, A. Louise; Mark, Felix C.; Linse, Katrin; Jernfors, Toni; Strugnell, Jan M. (2025) 'Circumpolar and Regional Seascape Drivers of Genomic Variation in a Southern Ocean Octopus'. Molecular Ecology, 34 (2). [DOI]
Journal Publication ResearchOnline@JCU
Schneller, Nadja M.; Strugnell, Jan M.; Field, Matt A.; Johannesson, Kerstin; Cooke, Ira (2025) 'Putting Structural Variants Into Practice: The Role of Chromosomal Inversions in the Management of Marine Environments'. Molecular Ecology, 34 (23). [DOI]
Journal Publication Open Access ResearchOnline@JCU
Barkan, Roy; Cooke, Ira; Watson, Sue Ann; Strugnell, Jan M. (2025) 'Synthesis of transcriptomic studies reveals a core response to heat stress in abalone (genus Haliotis)'. BMC Genomics, 26 (1). [DOI]
Journal Publication Open Access ResearchOnline@JCU
Macadam, Alexander; Morgans, Carys; Cheok, Jessica; Damjanovic, Katarina; Ciampaglia, Melissa; Toor, Maren; Laffy, Patrick; Cooke, Ira R.; Strugnell, Jan M.; Quigley, Kate M. (2025) 'Assessing the potential for “assisted gene flow” to enhance heat tolerance of multiple coral genera over three key phenotypic traits'. Biological Conservation, 306 . [DOI]
Journal Publication Open Access ResearchOnline@JCU
Kosch, Tiffany A.; Berger, Lee; Crawford, Andrew J.; Gilbert, Deon; Goodall, Damian; Hunter, David; McFadden, Michael; Abueg, Linelle; Formenti, Giulio; Collins, Joanna; Tilley, Tatiana; Jain, Nivesh; O'Toole, Brian; Whelan, Conor; Cooke, Ira; Muffato, Matthieu; Yates, Bethan; Fedrigo, Olivier; Balacco, Jennifer; Jarvis, Erich D.; Skerratt, Lee F. (2025) 'A chromosome-level reference genome for the critically endangered Southern Corroboree frog (Pseudophryne corroboree)'. Wellcome Open Research, 10 . [DOI]
Journal Publication Open Access ResearchOnline@JCU
Leiva, Carlos; Torda, Gergely; Zhou, Chengran; Pan, Yunrui; Harris, Jessica; Xiang, Xueyan; Tan, Shangjin; Tian, Wei; Hume, Benjamin; Miller, David J.; Li, Qiye; Zhang, Guojie; Cooke, Ira; Rodolfo-Metalpa, Riccardo (2025) 'Rapid Evolution in Action: Environmental Filtering Supports Coral Adaptation to a Hot, Acidic, and Deoxygenated Extreme Habitat'. Global Change Biology, 31 (3). [DOI]
Journal Publication Open Access ResearchOnline@JCU
Mason, Benjamin; Hayward, David C.; Moya, Aurelie; Cooke, Ira; Sorenson, Alanna; Brunner, Ramona; Andrade Rodriguez, Natalia; Huerlimann, Roger; Bourne, David G.; Schaeffer, Patrick; Grinblat, Mila; Ravasi, Timothy; Ueda, Nobuo; Tang, Sen-Lin; Ball, Eldon E.; Miller, David J. (2024) 'Microbiome manipulation by corals and other Cnidaria via quorum quenching'. Current Biology, 34 :3226-3232. [DOI]
Journal Publication ResearchOnline@JCU
Barkan, Roy; Cooke, Ira; Watson, Sue-Ann; Lau, Sally C.Y.; Strugnell, Jan M. (2024) 'Chromosome-scale genome assembly of the tropical abalone (Haliotis asinina)'. Scientific Data, 11 (1). [DOI]
Journal Publication Open Access ResearchOnline@JCU
Rennie, Benjamin; Nowland, Samantha J.; Cooke, Ira R.; Strugnell, Jan M. (2024) 'Filtration rate and bioremediatory potential of the tropical blacklip rock oyster Saccostrea lineage J'. Aquaculture Environment Interactions, 16 :133-144. [DOI]
Journal Publication Open Access ResearchOnline@JCU
Zhang, Jia; Schneller, Nadja M.; Field, Matt A.; Chan, Cheong Xin; Miller, David J.; Strugnell, Jan M.; Riginos, Cynthia; Bay, Line; Cooke, Ira (2024) 'Chromosomal inversions harbour excess mutational load in the coral, Acropora kenti, on the Great Barrier Reef'. Molecular Ecology, 33 (16). [DOI]
Journal Publication Open Access ResearchOnline@JCU
Calcino, Andrew; Cooke, Ira; Cowman, Peter; Higgie, Megan; Massault, Cecile; Schmitz, Ulf; Whittaker, Maxine; Field, Matt A. (2024) 'Harnessing genomic technologies for one health solutions in the tropics'. Globalization and Health, 20 . [DOI]
Journal Publication Open Access ResearchOnline@JCU
Lau, Sally C. Y.; Wilson, Nerida G.; Golledge, Nicholas R.; Naish, Tim R.; Watts, Phillip C.; Silva, Catarina N. S.; Cooke, Ira R.; Allcock, A. Louise; Mark, Felix C.; Linse, Katrin; Strugnell, Jan M. (2023) 'Genomic evidence for West Antarctic Ice Sheet collapse during the Last Interglacial'. Science, 382 :1384-1389. [DOI]
Journal Publication ResearchOnline@JCU
Whitelaw, Brooke; Finn, Julian K.; Zenger, Kyall R.; Cooke, Ira R.; Morse, Peter; Strugnell, Jan M. (2023) 'SNP data reveals the complex and diverse evolutionary history of the blue-ringed octopus genus (Octopodidae: Hapalochlaena) in the Asia-Pacific'. Molecular Phylogenetics and Evolution, 186 . [DOI]
Journal Publication Open Access ResearchOnline@JCU
Terrell, Alyx P.; Marangon, Emma; Webster, Nicole S.; Cooke, Ira; Quigley, Kate M. (2023) 'The promotion of stress tolerant Symbiodiniaceae dominance in juveniles of two coral species under simulated future conditions of ocean warming and acidification'. Frontiers in Ecology and Evolution, 11 . [DOI]
Journal Publication Open Access ResearchOnline@JCU
Matias, Ambrosio Melvin A.; Popovic, Iva; Thia, Joshua A.; Cooke, Ira R.; Torda, Gergely; Lukoschek, Vimoksalehi; Bay, Line; Kim, Sun; Riginos, Cynthia (2023) 'Cryptic diversity and spatial genetic variation in the coral Acropora tenuis and its endosymbionts across the Great Barrier Reef'. Evolutionary Applications, 16 (2):293-310. [DOI]
Journal Publication Open Access ResearchOnline@JCU
Schmidt, Casey A.; Cooke, Ira; Wilson, David T.; Miller, David J.; Peigneur, Steve; Tytgat, Jan; Field, Matthew; Takjoo, Rozita; Smout, Michael J.; Loukas, Alex; Daly, Norelle L. (2022) 'Newly Discovered Peptides from the Coral Heliofungia actiniformis Show Structural and Functional Diversity'. Journal of Natural Products, 85 (7):1789-1798. [DOI]
Journal Publication ResearchOnline@JCU
Whitelaw, Brooke L.; Jones, David B.; Guppy, Jarrod; Morse, Peter; Strugnell, Jan M.; Cooke, Ira R.; Zenger, Kyall (2022) 'High-Density Genetic Linkage Map of the Southern Blue-ringed Octopus (Octopodidae: Hapalochlaena maculosa)'. Diversity, 14 (12). [DOI]
Journal Publication Open Access ResearchOnline@JCU
Thomas, Luke; Underwood, Jim N.; Rose, Noah H.; Fuller, Zachary L.; Richards, Zoe T.; Dugal, Laurence; Grimaldi, Camille M.; Cooke, Ira R.; Palumbi, Stephen; Gilmour, James P. (2022) 'Spatially varying selection between habitats drives physiological shifts and local adaptation in a broadcast spawning coral on a remote atoll in Western Australia'. Science Advances, 8 (17). [DOI]
Journal Publication Open Access ResearchOnline@JCU
Zhang, Jia; Richards, Zoe T.; Adam, Arne A.S.; Chan, Cheong Xin; Shinzato, Chuya; Gilmour, James; Thomas, Luke; Strugnell, Jan M.; Miller, David J.; Cooke, Ira (2022) 'Evolutionary Responses of a Reef-building Coral to Climate Change at the End of the Last Glacial Maximum'. Molecular Biology and Evolution, 39 (10). [DOI]
Journal Publication Open Access ResearchOnline@JCU
Kuek, Felicity; Motti, Cherie; Zhang, Jia; Cooke, Ira R.; Todd, Jonathan D.; Miller, David J.; Bourne, David G.; Raina, Jean-Baptiste (2022) 'DMSP production by coral-associated bacteria'. Frontiers in Marine Science, 9 . [DOI]
Journal Publication Open Access ResearchOnline@JCU
Sidorczuk, Katarzyna; Gagat, Przemyslaw; Pietluch, Filip; Kala, Jakub; Rafacz, Dominik; Bakala, Laura; Slowik, Jadwiga; Kolenda, Rafal; Rodiger, Stefan; Fingerhut, Legana C.H.W.; Cooke, Ira R.; Mackiewicz, Pawel; Burdukiewicz, Michal (2022) 'Benchmarks in antimicrobial peptide prediction are biased due to the selection of negative data'. Briefings in Bioinformatics, 23 (5). [DOI]
Journal Publication Open Access ResearchOnline@JCU
Bongaerts, Pim; Cooke, Ira R.; Ying, Hua; Wels, Dagmar; den Haan, Stijn; Hernandez-Agreda, Alejandra; Brunner, Christopher A.; Dove, Sophie; Englebert, Norbert; Eyal, Gal; Foret, Sylvain; Grinblat, Mila; Hay, Kyra B.; Harii, Saki; Hayward, David C.; Lin, Yu; Morana, Mihaljevi C.; Moya, Aurelie; Muir, Paul; Sinniger, Frederic; Smallhorn-West, Patrick; Torda, Gergely; Ragan, Mark A.; van Oppen, Madeleine J.M.; Hoegh-Guldberg, Ove (2021) 'Morphological stasis masks ecologically divergent coral species on tropical reefs'. Current Biology, 31 (11):2286-2298.e8. [DOI]
Journal Publication Open Access ResearchOnline@JCU
Andrade Rodriguez, N.; Moya, A.; Jones, R.; Miller, D.J.; Cooke, I. (2021) 'The significance of genotypic diversity in coral competitive interaction: a transcriptomic perspective'. Frontiers in Ecology and Evolution, 9 . [DOI]
Journal Publication Open Access ResearchOnline@JCU
Grinblat, Mila; Cooke, Ira; Shlesinger, Tom; Ben-Zvi, Or; Loya, Yossi; Miller, David J.; Cowman, Peter F. (2021) 'Biogeography, reproductive biology and phylogenetic divergence within the Fungiidae (mushroom corals)'. Molecular Phylogenetics and Evolution, 164 . [DOI]
Journal Publication ResearchOnline@JCU
Mason, B.; Cooke, I.; Moya, A.; Augustin, R.; Lin, M.F.; Satoh, N.; Bosch, T.C.G.; Bourne, D.G.; Hayward, D.C.; Andrade, N.; Forêt, S.; Ying, H.; Ball, E.E.; Miller, D.J. (2021) 'AmAMP1 from Acropora millepora and damicornin define a family of coral-specific antimicrobial peptides related to the Shk toxins of sea anemones'. Developmental and Comparative Immunology, 114 . [DOI]
Journal Publication ResearchOnline@JCU
Schmidt, Casey A.; Wilson, David T.; Cooke, Ira; Potriquet, Jeremy; Tungatt, Katie; Muruganandah, Visai; Boote, Chloe; Kuek, Felicity; Miles, John J.; Kupz, Andreas; Ryan, Stephanie; Loukas, Alex; Bansal, Paramjit S.; Takjoo, Rozita; Miller, David J.; Peigneur, Steve; Tytgat, Jan; Daly, Norelle (2020) 'Identification and characterization of a peptide from the stony coral Heliofungia actiniformis'. Journal of Natural Products, 83 (11):3454-3463. [DOI]
Journal Publication ResearchOnline@JCU
Cooke, Ira; Ying, Hua; Forêt, Sylvain; Bongaerts, Pim; Strugnell, Jan M.; Simakov, Oleg; Zhang, Jia; Field, Matt A.; Rodriguez-Lanetty, Mauricio; Bell, Sara C.; Bourne, David G.; van Oppen, Madeleine J.H.; Ragan, Mark A.; Miller, David J. (2020) 'Genomic signatures in the coral holobiont reveal host adaptations driven by Holocene climate change and reef specific symbionts'. Science Advances, 6 (48). [DOI]
Journal Publication Open Access ResearchOnline@JCU
Whitelaw, Brooke L.; Cooke, Ira R.; Finn, Julian; da Fonseca, Rute R.; Ritschard, Elena A.; Gilbert, M. T. P.; Simakov, Oleg; Strugnell, Jan M. (2020) 'Adaptive venom evolution and toxicity in octopods is driven by extensive novel gene formation, expansion, and loss'. GigaScience, 9 (11). [DOI]
Journal Publication Open Access ResearchOnline@JCU
Fingerhut, Legana C. H. W.; Miller, David J.; Strugnell, Jan M.; Daly, Norelle L.; Cooke, Ira R. (2020) 'ampir: an R package for fast genome-wide prediction of antimicrobial peptides'. Bioinformatics, 36 (21). [DOI]
Journal Publication ResearchOnline@JCU
Caruana, Nikeisha J.; Strugnell, Jan M.; Finn, Julian; Faou, Pierre; Plummer, Kim M.; Cooke, Ira R. (2020) 'Quantitative proteomic analysis of the slime and ventral mantle glands of the Striped Pyjama squid (Sepioloidea lineolata)'. Journal of Proteome Research, 19 :1491-1501. [DOI]
Journal Publication ResearchOnline@JCU
Shiel, Brett P.; Cooke, Ira R.; Hall, Nathan E.; Robinson, Nicholas A.; Strugnell, Jan M. (2020) 'Gene expression differences between abalone that are susceptible and resilient to a simulated heat wave event'. Aquaculture, 526 . [DOI]
Journal Publication ResearchOnline@JCU
Mohamed, Amin R.; Chan, Cheong Xin; Ragan, Mark A.; Zhang, Jia; Cooke, Ira; Ball, Eldon E.; Miller, David J. (2020) 'Comparative transcriptomic analyses of Chromera and Symbiodiniaceae'. Environmental Microbiology Reports, 12 (4):534-443. [DOI]
Journal Publication ResearchOnline@JCU
Robbins, Steven J.; Singleton, Caitlin M.; Chan, Cheong Xin; Messer, Lauren F.; Geers, Aileen U.; Ying, Hua; Baker, Alexander; Bell, Sara C.; Morrow, Kathleen M.; Ragan, Mark A.; Miller, David J.; Forêt, Sylvain; Voolstra, Christian R.; Tyson, Gene W.; Bourne, David G.; Ball, Eldon; Beeden, Roger; Berumen, Michael; Aranda, Manuel; Ravasi, Timothy; Bongaerts, Pim; Hoegh-Guldberg, Ove; Cooke, Ira; Leggat, Bill; Sprungala, Susanne; Fitzgerald, Anna; Shang, Catherine; Lundgren, Petra; Fyffe, Theresa; Rubino, Francesco; van Oppen, Madeleine; Weynberg, Karen; Bells, Sara C. (2019) 'A genomic view of the reef-building coral Porites lutea and its microbial symbionts'. Nature Microbiology, 4 (12):2090-2100. [DOI]
Journal Publication ResearchOnline@JCU
Ying, Hua; Hayward, David C.; Cooke, Ira; Wang, Weiwen; Moya, Aurelie; Siemering, Kirby R.; Sprungala, Susanne; Ball, Eldon E.; Foret, Sylvain; Miller, David J. (2019) 'The whole-genome sequence of the coral Acropora millepora'. Genome Biology and Evolution, 11 (5):1374-1379. [DOI]
Journal Publication Open Access ResearchOnline@JCU
Jaspers, Cornelia; Fraune, Sebastian; Arnold, A. Elizabeth; Miller, David J.; Bosch, Thomas C.G.; Voolstra, Christian R.; Adamska, Maja; Ainsworth, Tracy; Ball, Eldon; Boote, Chlöe; Bourne, David; Butterfield, Nicholas J.; Chan, Cheong Xin; Cooke, Ira; Cowman, Peter F.; Darling, Aaron; Davy, Simon K.; Mohamed, Amin; Fabricius, Katharina; Valero Fortunato, Sofia V.; Hernandez Agreda, Alejandra; Hoogenboom, Mia; Moya, Aurelie; Pita, Lucia; Ragan, Mark A.; Robbins, Steven J.; Andrade Rodriguez, Natalia R.; Sakamaki, Kazuhiro; Schoepf, Verena; Seemann, Thorsten; Shinzato, Chuya; Stolarski, Jarosław; Strugnell, Jan; Takahashi, Shunichi; Tang, Sen-Lin; Webster, Nicole N; Whitelaw, Brooke; Ying, Hua (2019) 'Resolving structure and function of metaorganisms through a holistic framework combining reductionist and integrative approaches'. Zoology, 133 :81-87. [DOI]
Journal Publication Open Access ResearchOnline@JCU
Caruana, Nikeisha J.; Strugnell, Jan M.; Faou, Pierre; Finn, Julian; Cooke, Ira R. (2019) 'Comparative proteomic analysis of slime from the striped pyjama squid, Sepioloidea lineolata, and the southern bottletail squid, Sepiadarium austrinum (Cephalopoda: Sepiadariidae)'. Journal of Proteome Research, 18 (3):890-899. [DOI]
Journal Publication ResearchOnline@JCU
Whitelaw, Brooke L.; Cooke, Ira R.; Finn, Julian; Zenger, Kyall; Strugnell, J.M. (2019) 'The evolution and origin of tetrodotoxin acquisition in the blue-ringed octopus (genus Hapalochlaena)'. Aquatic Toxicology, 206 :114-122. [DOI]
Journal Publication ResearchOnline@JCU
Ritschard, Elena A.; Whitelaw, Brooke; Albertin, Caroline B.; Cooke, Ira R.; Strugnell, Jan M.; Simakov, Oleg (2019) 'Coupled genomic evolutionary histories as signatures of organismal innovations in Cephalopods co-evolutionary signatures across levels of genome organization may shed light on functional linkage and origin of Cephalopod novelties'. BioEssays, 41 . [DOI]
Journal Publication Open Access ResearchOnline@JCU
Cooke, Ira; Mead, Oliver; Whalen, Casey; Boote, Chloe; Moya, Aurelie; Ying, Hua; Robbins, Steven; Strugnell, Jan M.; Darling, Aaron; Miller, David; Voolstra, Christian; Adamska, Maya (2019) 'Molecular techniques and their limitations shape our view of the holobiont'. Zoology, 137 . [DOI]
Journal Publication ResearchOnline@JCU
Liu, Huanle; Stephens, Timothy G.; González-Pech, Raúl A.; Beltran, Victor H.; Lapeyre, Bruno; Bongaerts, Pim; Cooke, Ira; Aranda, Manuel; Bourne, David G.; Forêt, Sylvain; Miller, David J.; van Oppen, Madeleine J.H.; Voolstra, Christian R.; Ragan, Mark A.; Chan, Cheong Xin (2018) 'Symbiodinium genomes reveal adaptive evolution of functions related to coral-dinoflagellate symbiosis'. Communications Biology, 1 . [DOI]
Journal Publication Open Access ResearchOnline@JCU
Woodings, Laura N.; Murphy, Nicholas P.; Doyle, Stephen R.; Hall, Nathan E.; Robinson, Andrew J.; Liggins, Geoffrey W.; Green, Bridget S.; Cooke, Ira R.; Bell, James J.; Strugnell, Jan M. (2018) 'Outlier SNPs detect weak regional structure against a background of genetic homogeneity in the Eastern Rock Lobster, Sagmariasus verreauxi'. Marine Biology, 165 (12). [DOI]
Journal Publication ResearchOnline@JCU
Ying, Hua; Cooke, Ira; Sprungala, Susanne; Wang, Weiwen; Hayward, David C.; Tang, Yurong; Huttley, Gavin; Ball, Eldon E.; Forêt, Sylvain; Miller, David J. (2018) 'Comparative genomics reveals the distinct evolutionary trajectories of the robust and complex coral lineages'. Genome Biology, 19 . [DOI]
Journal Publication Open Access ResearchOnline@JCU
Fingerhut, Legana C.H.W.; Strugnell, Jan M.; Faou, Pierre; Labiaga, Àlvaro Roura; Zhang, Jia; Cooke, Ira R. (2018) 'Shotgun proteomics analysis of saliva and salivary gland tissue from the common octopus Octopus vulgaris'. Journal of Proteome Research, 17 (11):3866-3876. [DOI]
Journal Publication ResearchOnline@JCU
Nuez-Ortín, Waldo G.; Carter, Chris G.; Nichols, Peter D.; Cooke, Ira R.; Wilson, Richard (2018) 'Liver proteome response of pre-harvest Atlantic salmon following exposure to elevated temperature'. BMC Genomics, 19 . [DOI]
Journal Publication Open Access ResearchOnline@JCU
Shiel, Brett P.; Hall, Nathan E.; Cooke, Ira R.; Robinson, Nicholas A.; Strugnell, Jan M. (2017) 'Epipodial tentacle gene expression and predetermined resilience to summer mortality in the commercially important greenlip abalone, Haliotis laevigata'. Marine Biotechnology, 19 (2):191-205. [DOI]
Journal Publication Open Access ResearchOnline@JCU
Lin, Mei-Fang; Moya, Aurelie; Ying, Hua; Chen, Chaolun Allen; Cooke, Ira; Ball, Eldon E.; Forȇt, Sylvain; Miller, David J. (2017) 'Analyses of corallimorpharian transcriptomes provide new perspectives on the evolution of calcification in the Scleractinia (corals)'. Genome Biology and Evolution, 9 (1):150-160. [DOI]
Journal Publication Open Access ResearchOnline@JCU
Chambers, Matthew C.; Jagtop, Pratik D.; Johnson, James E.; McGowan, Thomas; Kumar, Praveen; Onsongo, Getiria; Guerrero, Candace R.; Barsnes, Harald; Vaudel, Marc; Martens, Lennart; Grüning, Björn; Cooke, Ira; Heydarian, Mohammad; Reddy, Karen L.; Griffin, Timothy J. (2017) 'An accessible proteogenomics informatics resource for cancer researchers'. Cancer Research, 77 (21):E43-E46. [DOI]
Journal Publication ResearchOnline@JCU
Shiel, Brett P.; Hall, Nathan E.; Cooke, Ira R.; Robinson, Nicholas A.; Stone, David A.J.; Strugnell, Jan M. (2017) 'The effect of commercial, natural and grape seed extract supplemented diets on gene expression signatures and survival of greenlip abalone (Haliotis laevigata) during heat stress'. Aquaculture, 479 :798-807. [DOI]
Journal Publication ResearchOnline@JCU
Cameron, Timothy C.; Cooke, Ira; Faou, Pierre; Toet, Hayley; Piedrafita, David; Young, Neil; Rathinasamy, Vignesh; Beddoe, Travis; Anderson, Glenn; Dempster, Robert; Spithill, Terry W. (2017) 'A novel ex vivo immunoproteomic approach characterising Fasciola hepatica tegumental antigens identified using immune antibody from resistant sheep'. International Journal for Parasitology, 47 (9):555-567. [DOI]
Journal Publication ResearchOnline@JCU
Nuez-Ortin, Waldo G.; Carter, Chris G.; Wilson, Richard; Cooke, Ira R.; Amoroso, Gianluca; Cobcroft, Jennifer M.; Nichols, Peter D. (2017) 'Triploid Atlantic salmon shows similar performance, fatty acid composition and proteome response to diploids during early freshwater rearing'. Comparative Biochemistry and Physiology Part D: Genomics and Proteomics, 22 :67-77. [DOI]
Journal Publication ResearchOnline@JCU
Schneider, Maria Victoria; Griffin, Phillippa C.; Tyagi, Sonika; Flannery, Madison; Dayalan, Saravanan; Gladman, Simon; Watson-Haigh, Nathan; Bayer, Philipp E.; Charleston, Michael; Cooke, Ira; Cook, Rob; Edwards, Richard J.; Edwards, David; Gorse, Dominique; McConville, Malcolm; Powell, David; Wilkins, Marc R.; Lonie, Andrew (2017) 'Establishing a distributed national research infrastructure providing bioinformatics support to life science researchers in Australia'. Briefings in Bioinformatics, 2017 . [DOI]
Journal Publication Open Access ResearchOnline@JCU
Dagonnier, Marie; Cooke, Ira Robin; Faou, Pierre; Sidon, Tara Kate; Dewey, Helen Margaret; Donnan, Geoffrey Alan; Howells, David William (2017) 'Discovery and longitudinal evaluation of candidate biomarkers for ischaemic stroke by mass spectrometry-based proteomics'. Biomarker Insights, 12 . [DOI]
Journal Publication Open Access ResearchOnline@JCU
Nguyen, Vinh A.; Carey, Leeanne M.; Giummarra, Loretta; Faou, Pierre; Cooke, Ira; Howells, David W.; Tse, Tamara; Macaulay, S. Lance; Ma, Henry; Davis, Stephen M.; Donnan, Geoffrey A.; Crewther, Sheila G. (2016) 'A pathway proteomic profile of ischemic stroke survivors reveals innate immune dysfunction in association with mild symptoms of depression: a pilot study'. Frontiers in Neurology, 7 :1-16. [DOI]
Journal Publication Open Access ResearchOnline@JCU
Shafee, Thomas; Cooke, Ira (2016) 'AlignStat: a web-tool and R package for statistical comparison of alternative multiple sequence alignments'. BMC Bioinformatics, 17 (1):1-6. [DOI]
Journal Publication Open Access ResearchOnline@JCU
Nuez Ortin, Waldo; Carter, Chris G.; Wilson, Richard; Cooke, Ira; Nichols, Peter D. (2016) 'Preliminary validation of a high docosahexaenoic acid (DHA) and -linolenic acid (ALA) dietary oil blend: tissue fatty acid composition and liver proteome response in Atlantic salmon (Salmo salar) smolts'. PLoS ONE, 11 (8):1-27. [DOI]
Journal Publication Open Access ResearchOnline@JCU
Caruana, Nikeisha J.; Cooke, Ira R.; Faou, Pierre; Finn, Julian; Hall, Nathan E.; Norman, Mark; Pineda, Sandy S.; Strugnell, Jan M. (2016) 'A combined proteomic and transcriptomic analysis of slime secreted by the southern bottletail squid, Sepiadarium austrinum (Cephalopoda)'. Journal of Proteomics, 148 :170-182. [DOI]
Journal Publication ResearchOnline@JCU
Whitelaw, Brooke Lauren; Strugnell, Jan M.; Faou, Pierre; da Fonseca, Rute R.; Hall, Nathan; Norman, Mark; Finn, Julian; Cooke, Ira Robin (2016) 'Combined transcriptomic and proteomic analysis of the posterior salivary gland from the southern blue-ringed octopus and the southern sand octopus'. Journal of Proteome Research, 15 (9):3284-3297. [DOI]
Journal Publication ResearchOnline@JCU
Murugesan, Selvaraaju; Tay, David B.H.; Cooke, Ira; Faou, Pierre (2015) 'Application of dual tree complex wavelet transform in tandem mass spectrometry'. Computers in Biology and Medicine, 63 :36-41. [DOI]
Journal Publication ResearchOnline@JCU
Shiel, Brett P.; Hall, Nathan E.; Cooke, Ira R.; Robinson, Nicholas A; Strugnell, Jan M. (2015) 'De novo characterisation of the greenlip abalone transcriptome (Haliotis laevigata) with a focus on the heat shock protein 70 (HSP70) family'. Marine Biotechnology, 17 :23-32. [DOI]
Journal Publication ResearchOnline@JCU
Cooke, Ira R; Jones, Dan; Bowen, Joanna K; Deng, Cecilia; Faou, Pierre; Hall, Nathan E; Jayachandran, Vignesh; Liem, Michael; Taranto, Adam P; Plummer, Kim M; Mathivanan, Suresh (2014) 'Proteogenomic analysis of the Venturia pirina (pear scab fungus) secretome reveals potential effectors'. Journal of Proteome Research, 13 (8):3635-3644. [DOI]
Journal Publication ResearchOnline@JCU
Cooke, Ira R.; Mattison, Elizabeth H.A.; Audsley, Eric; Bailey, Alison P.; Freckleton, Robert P.; Graves, Anil R.; Morris, Joe; Queenborough, Simon A.; Sandars, Daniel L.; Siriwardena, Gavin M.; Trawick, Paul; Watkinson, Andrew R.; Sutherland, William J. (2013) 'Empirical test of an agricultural landscape model: the importance of farmer preference for risk aversion and crop complexity'. SAGE Open, 3 :1-16. [DOI]
Journal Publication Open Access ResearchOnline@JCU
Robinson, Nick; Smith, Ben; Cooke, Ira; Strugnell, Jan (2013) 'A snail's pace: a preliminary analysis of the effects of stress and genetics on movement of Haliotis'. Aquaculture, 376-379 :25-35. [DOI]
Journal Publication ResearchOnline@JCU
Appleby, Sarah L.; Cockshell, Michaelia P.; Pippal, Jyotsna B.; Thompson, Emma J.; Barrett, Jeffrey M.; Tooley, Katie; Sen, Shaundeep; Sun, Wai Yan; Grose, Randall; Nicholson, Ian; Levina, Vitalina; Cooke, Ira; Talbo, Gert; Lopez, Angel F.; Bonder, Claudine S. (2012) 'Characterization of a distinct population of circulating human non-adherent endothelial forming cells and their recruitment via intercellular adhesion molecule-3'. PLoS ONE, 7 (11). [DOI]
Journal Publication Open Access ResearchOnline@JCU
Siriwardena, Gavin M.; Cooke, Ira R.; Sutherland, William J. (2012) 'Landscape, cropping and field boundary influences on bird abundance'. Ecography, 35 (2):162-173. [DOI]
Journal Publication ResearchOnline@JCU
Allcock, A. Louise; Cooke, Ira R.; Strugnell, Jan M. (2011) 'What can the mitochondrial genome reveal about higher-level phylogeny of the molluscan class Cephalopoda?'. Zoological Journal of the Linnean Society, 161 (3):573-586. [DOI]
Journal Publication ResearchOnline@JCU
Robinson, Nick A.; Hall, Nathan E.; Ross, Elizabeth M.; Cooke, Ira R.; Shiel, Brett P.; Robinson, Andrew J.; Strugnell, Jan M. (2016) 'The complete mitochondrial genome of Haliotis laevigata (Gastropoda: Haliotidae) using MiSeq and HiSeq sequencing' Mitochondrial DNA Part A: DNA mapping, sequencing and analysis, 27 :437-438. [DOI]
Journal Contribution ResearchOnline@JCU
Hall, Nathan E.; Hanzak, Jan; Allcock, A. Louise; Cooke, Ira R.; Ogura, Atsushi; Strugnell, Jan M. (2016) 'The complete mitochondrial genome of the pygmy squid, Idiosepius (Cephalopoda: Decapodiformes): the first representative from the family Idiosepiidae' Mitochondrial DNA Part A: DNA mapping, sequencing and analysis, 27 (1) :5-6. [DOI]
Journal Contribution ResearchOnline@JCU
Boekel, Jorrit; Chilton, John; Cooke, Ira; Horvatovich, Peter; Jagtap, Pratik; Kall, Lukas; Lehtiö, Janne; Lukasse, Pieter; Moerland, Perry; Griffin, Timothy (2015) 'Multi-omic data analysis using Galaxy' Nature Biotechnology, 33 :137-139. [DOI]
Journal Contribution ResearchOnline@JCU
Cooke, Ira R.; Whitelaw, Brooke; Norman, Mark; Caruana, Nikeisha; Strugnell, Jan (2015) 'Toxicity in cephalopods' In: Cooke, Ira R., Whitelaw, Brooke, Norman, Mark, Caruana, Nikeisha, and Strugnell, Jan (2015) Toxicity in cephalopods. In: Gopalakrishnakone, P., and Malhotra, Anita, (eds.) Evolution of Venomous Animals and Their Toxins. Toxinology . Springer, Leiden, The Netherlands, pp. 1-15(Eds.). Evolution of Venomous Animals and Their Toxins. Leiden, The Netherlands : Springer. [DOI]