PHTM - Tropical Health


Patricia Graves

Patricia Graves

Dave Sellars

Dave Sellars

Richard Bradbury

Richard Bradbury

Ending the neglect – setting the platform for strongyloidiasis elimination in Australia
Richard Bradbury
01 Jan 2024 - 31 Dec 2028
Strongyloidiasis is caused by parasitic nematodes (roundworms) of the genus Strongyloides and is considered to be one of the most neglected of the neglected tropical diseases (NTDs). There are two main Strongyloides species that cause human infection; S. stercoralis and S. fuelleborni. In Australia, S. stercoralis is the infecting species that disproportionately affects remote Indigenous communities, with the prevalence ranging from 10-60%. The lifecycle and transmission is complex with both a parasitic cycle and a free-living cycle. This is further complicated by autoinfection and the possibility of zoonotic transmission– recent genetic evidence suggests the possibility of a dog reservoir. These factors coupled with less than ideal diagnostics and treatment options (Ivermectin and Albendazole) where there is evidence of treatment failures, the spectre of emerging resistance and their inability to prevent reinfection, all have implications for control and elimination efforts. It is our central thesis that strongyloidiasis is a zoonotic neglected tropical disease of public health importance in Australia and that an integrated interdisciplinary “One Health” approach is required for its elimination.
Reseracher: Richard Bradbury (Associate Professor, Tropical Public Health and Medicine)
Start Date: 01 Jan 2003
End Date: 01 Jan 2010
Reseracher: Richard Bradbury (Associate Professor, Tropical Public Health and Medicine)
Start Date: 01 Jan 1995
End Date: 01 Jan 1997
Reseracher: Dave Sellars (Senior Lecturer - Environmental Health)
End Date: 01 Jan 1993
Reseracher: Dave Sellars (Senior Lecturer - Environmental Health)
End Date: 01 Jan 2006
Reseracher: Steph Topp (Professor)
Start Date: 01 Jan 2019
Start Date: 01 Jan 2018