photo
Projects

0

Publications

59

Awards

0

Contact Details

Associate Professor

    Research

    Research Interests

    Hepatocellular carcinoma and therapeutic approaches

    Muscle development and disease

    Cancer Stem Cells

    Research Collaborators and Partners
    Professor Jacob George
    The University of Sydney
    Professor Nathan Subramaniam
    Queensland University of Technology

    Teaching

    Teaching Interests

    Cancer Biology and Biochemistry

    Research Advisor Accreditation
    Advisor Type

    Mentor

    Research Advisor Accreditation
    Role

    Chair; Independent Academic

    Taught Modules
    [BC3102] Molecular Basis of DiseaseLecturer
    2025
    [BC5102] Advanced Molecular Basis of DiseaseLecturer
    2025
    [MD1010] Introduction to Integrated Medical Studies Part 1 of 2Lecturer
    2022
    [MD1010] Introduction to Integrated Medical Studies Part 1 of 2Lecturer
    2025
    [MD1020] Introduction to Integrated Medical Studies Part 2 of 2Lecturer
    2025
    [BM4011] Biomedical Science Honours (Part-Time) Part 2 of 4Lecturer
    2025
    [BM4010] Biomedical Science Honours (Part-Time) Part 1 of 4Lecturer
    2025
    [BC3102] Molecular Basis of DiseaseLecturer
    2026
    [MD3011] Introduction to Clinical Healthcare Part 1 of 2Lecturer
    2026
    [MD1020] Introduction to Integrated Medical Studies Part 2 of 2Lecturer
    2026
    [MD1010] Introduction to Integrated Medical Studies Part 1 of 2Lecturer
    2026
    Available Projects
    Developing new proteins through precision fermentation - Molecular and Cell Biology
    Date Added
    30 Mar 2026
    Investigating new genes and therapies in Liver Cancer - Molecular Genetics
    Date Added
    11 Oct 2024

    Output

    Testing Cell Migration, Invasion, Proliferation, and Apoptosis in Hepatic Stellate Cells
    2023
    Wankell, Miriam; Hebbard, Lionel (2023) Testing Cell Migration, Invasion, Proliferation, and Apoptos. New York, NY, USA: [Non-Research Book Chapter] [DOI] ...
    Other Publication ResearchOnline@JCU
    Collagen Biomaterials: From Traditional Animal Sources to Marine and Recombinant Alternatives
    2026
    Rezaeivandchali, Noushin; Hebbard, Lionel; McFarlane, Craig (2026) 'Collagen Biomaterials: From Trad. International Journal of Bioma, 2026 . [DOI] ...
    Journal Publication Open Access ResearchOnline@JCU
    Characterisation of Lates calcarifer primary myoblast proliferation and differentiation from direct cell isolation
    2026
    Trace, Craig; Wankell, Miriam; McFarlane, Craig; Hebbard, Lionel (2026) 'Characterisation of Lates c. In Vitro Cellular and Dev, . [DOI] ...
    Journal Publication ResearchOnline@JCU
    From Cell Line to Fillet: A Review of Biological and Engineering Strategies in Cultivated Seafood
    2026
    Trace, Angela; Wankell, Miriam; McFarlane, Craig; Hebbard, Lionel (2026) 'From Cell Line to Fillet: . Food Bioengineering, . [DOI] ...
    Journal Publication Open Access ResearchOnline@JCU
    Quantification of Sarcopenia using Chest Computed Tomography of the Pectoralis Major Muscle as a Prognostic Tool for Cardiac Surgery Outcomes
    2026
    Nezafati, Pouya; Saxena, Pankaj; Raman, Jaishankar; Hebbard, Lionel; Draper, Narelle; McFarlane, Cra...
    Journal Publication Open Access ResearchOnline@JCU
    The challenges of using fish cells for cultivated seafood production
    2025
    Trace, Angela; Wankell, Miriam; McFarlane, Craig; Hebbard, Lionel (2025) 'The challenges of using fi. Food Science and Biotech, 34 :1565-1579. [DOI] ...
    Journal Publication ResearchOnline@JCU
    TARGET-SL: precision essential gene prediction using driver prioritisation and synthetic lethality
    2025
    Gillman, Rhys; Schmitz, Ulf; Field, Matt A.; Hebbard, Lionel (2025) 'TARGET-SL: precision essential . Briefings in Bioinformatics, 26 (3). [DOI] ...
    Journal Publication Open Access ResearchOnline@JCU
    A New Model to Investigate the Action of Radiation and Cigarette Smoke on Head and Neck Cancer Cells
    2025
    Lopes Floro, Kylie; Gillman, Rhys; Wankell, Miriam; Dewdney, Brittany; Chilkuri, Madhavi; Shackelfor...
    Journal Publication Open Access ResearchOnline@JCU
    Getting to the heart of sarcopenia and cardiovascular disease
    2025
    Nezafati, Pouya; Saxena, Pankaj; Raman, Jaishankar; Hebbard, Lionel; McFarlane, Craig (2025) 'Gettin. Agin, ....
    Journal Publication Open Access ResearchOnline@JCU
    Recent Advances in Cancer Fusion Transcript Detection
    2023
    Dorney, Ryley; Dhungel, Bijay P.; Rasko, John E.J.; Hebbard, Lionel; Schmitz, Ulf (2023) 'Recent Adv. Briefing, 24 (1)...
    Journal Publication Open Access ResearchOnline@JCU
    Identifying cancer driver genes in individual tumours
    2023
    Gillman, Rhys; Field, Matt A.; Schmitz, Ulf; Karamatic, Rozemary; Hebbard, Lionel (2023) 'Identifyin. Computat, 21 :50...
    Journal Publication Open Access ResearchOnline@JCU
    Immune checkpoint inhibitors in HCC: Cellular, molecular and systemic data
    2022
    Harkus, Uasim; Wankell, Miriam; Palamuthusingam, Pranavan; McFarlane, Craig McFarlane; Hebbard, Lion...
    Journal Publication ResearchOnline@JCU
    An aptamer-based drug delivery agent (CD133-apt-Dox) selectively and effectively kills liver cancer stem-like cells
    2021
    Zhou, Gang; Da Won Bae, Sarah; Nguyen, Romario; Huo, Xiaoqi; Han, Shuanglin; Zhang, Zhiqiang; Hebbar...
    Journal Publication ResearchOnline@JCU
    Cell adhesion an important determinant of myogenesis and satellite cell activity
    2021
    Taylor, Lauren; Wankell, Miriam; Saxena, Pankaj; McFarlane, Craig McFarlane; Hebbard, Lionel (2021) ...
    Journal Publication ResearchOnline@JCU
    Targeting the PI3K/Akt/mTOR pathway in hepatocellular carcinoma
    2021
    Sun, Eun Jin; Wankell, Miriam; Palamuthusingam, Pranavan; McFarlane, Craig; Hebbard, Lionel (2021) '....
    Journal Publication Open Access ResearchOnline@JCU
    The role of DNA damage and repair in liver cancer
    2020
    Gillman, Rhys; Lopes Floro, Kylie; Wankell, Miriam; Hebbard, Lionel (2020) 'The role of DNA damage a. Biochimica et Biophysi, 1875 (1). [DOI] ...
    Journal Publication ResearchOnline@JCU
    A sweet connection? Fructose’s role in hepatocellular carcinoma
    2020
    Dewdney, Brittany; Roberts, Alexandra; Qiao, Liang; George, Jacob; Hebbard, Lionel (2020) 'A sweet c. Biomole, 10 (4...
    Journal Publication Open Access ResearchOnline@JCU
    The effects of fructose and metabolic inhibition on hepatocellular carcinoma
    2020
    Dewdney, Brittany; Alanzay, Mohammed; Gillman, Rhys; Walker, Sarah; Wankell, Miriam; Qiao, Liang; Ge...
    Journal Publication Open Access ResearchOnline@JCU
    Targeting mTOR and Src restricts hepatocellular carcinoma growth in a novel murine liver cancer model
    2019
    Walker, Sarah; Wankell, Miriam; White, Rose; Ho, Vikki; Deo, Nikita; Devine, Carol; Dewdney, Brittan...
    Journal Publication Open Access ResearchOnline@JCU
    The role of micronutrients in the infection and subsequent response to hepatitis C virus
    2019
    Gupta, Sunil; Read, Scott A.; Shackel, Nicholas A.; Hebbard, Lionel; George, Jacob; Ahlenstiel, Golo...
    Journal Publication Open Access ResearchOnline@JCU
    The role of obesity in inflammatory bowel disease
    2019
    Kreuter, Roxane; Wankell, Miriam; Ahlenstiel, Golo; Hebbard, Lionel (2019) 'The role of obesity in i. Biochimica et Biophysi, 1865 (1):63-72. [DO ...
    Journal Publication ResearchOnline@JCU
    Aptamers as targeting ligands and therapeutic molecules for overcoming drug resistance in cancers
    2018
    Zhou, Gang; Latchoumanin, Olivier; Hebbard, Lionel; Duan, Wei; Liddle, Christopher; George, Jacob; Q...
    Journal Publication ResearchOnline@JCU
    The role of AdipoR1 and AdipoR2 in liver fibrosis
    2018
    Alzahrani, Badr; Iseli, Tristan; Ramezani-Moghadam, Mehdi; Ho, Vikki; Wankell, Miriam; Sun, Eun Jin;...
    Journal Publication Open Access ResearchOnline@JCU
    Aptamer-based therapeutic approaches to target cancer wtem cells
    2017
    Zhou, Gang; Latchoumanin, Olivier; Bagdesar, Mary; Hebbard, Lionel; Duan, Wei; Liddle, Christopher; ...
    Journal Publication Open Access ResearchOnline@JCU
    Overcoming treatment resistance in cancer: current understanding and tactics
    2017
    Wu, Guang; Wilson, George; George, Jacob; Liddle, Christopher; Hebbard, Lionel; Liang, Qiao (2017) '....
    Journal Publication ResearchOnline@JCU
    The functional roles of T-cadherin in mammalian biology
    2017
    Sternberg, Jade; Wankell, Miriam; Subramaniam, V. Nathan; Hebbard, Lionel (2017) 'The functional rol. AIMS Molecular S, 4 (1):62-81. ...
    Journal Publication Open Access ResearchOnline@JCU
    Recent clinical trials utilizing chimeric antigen receptor T cells therapies against solid tumors
    2017
    Han, Shuanglin; Latchoumanin, Olivier; Wu, Guang; Zhou, Gang; Hebbard, Lionel; George, Jacob; Qiao, ...
    Journal Publication ResearchOnline@JCU
    Adiponectin confers protection from acute colitis and restricts a B cell immune response
    2017
    Obeid, Stephanie; Wankell, Miriam; Charrez, Berenice; Sternberg, Jade; Kreuter, Roxane; Esmaili, Sae...
    Journal Publication ResearchOnline@JCU
    Dysregulated long noncoding RNAs(lncRNAs) in hepatocellular carcinoma: implications for tumorigenesis, disease progression, and liver cancer stem cells
    2017
    Huo, Xiaoqi; Han, Shuanglin; Wu, Guang; Latchoumanin, Oliveir; Zhou, Gang; Hebbard, Lionel; George, ...
    Journal Publication Open Access ResearchOnline@JCU
    Aptamers: a promising chemical antibody for cancer therapy
    2016
    Zhou, Gang; Wilson, George; Hebbard, Lionel; Duan, Wei; Liddle, Christopher; George, Jacob; Qiao, Li...
    Journal Publication Open Access ResearchOnline@JCU
    Hepatocellular carcinoma and non-alcoholic steatohepatitis: the state of play
    2016
    Charrez, Bérénice; Qiao, Liang; Hebbard, Lionel (2016) 'Hepatocellular carcinoma and non-alcoholic s. World Journal of Gastroenterology, 22 (8):2494-2502. [DOI] ...
    Journal Publication Open Access ResearchOnline@JCU
    Oct4 is a reliable marker of liver tumor propagating cells in hepatocellular carcinoma
    2015
    Wu, Guang; Wilson, George; Zhou, Gang; Hebbard, Lionel; George, Jacob; Qiao, Liang; ; (2015) 'Oct4 . Dis, 2...
    Journal Publication ResearchOnline@JCU
    The role of fructose in metabolism and cancer
    2015
    Charrez, Bérénice; Qiao, Liang; Hebbard, Lionel (2015) 'The role of fructose in metabolism and cance. Hormone molecular biology and clinical inv, 22 (2):79-89. [DOI] ...
    Journal Publication ResearchOnline@JCU
    Effect of resveratrol on experimental non-alcoholic steatohepatitis
    2015
    Heebøll, Sara; Thomsen, Karen Louise; Clouston, Andrew; Sundelin, Elias Immanuel; Radko, Yulia; Chri...
    Journal Publication ResearchOnline@JCU
    Adiponectin reduces hepatic stellate cell migration by promoting tissue inhibitor of metalloproteinase-1 (TIMP-1) secretion
    2015
    Ramezani-Moghadam, Mehdi; Wang, Jianhua; Ho, Vikki; Iseli, Tristan J.; Alzahrani, Badr; Xu, Aimin; V...
    Journal Publication ResearchOnline@JCU
    Non-viral causes of liver cancer: does obesity led inflammation play a role
    2014
    Alzahrani, Badr; Iseli, Tristan J.; Hebbard, Lionel W. (2014) 'Non-viral causes of liver cancer: doe. Cancer Letters, 345 (2):223-229. [DOI] ...
    Journal Publication ResearchOnline@JCU
    Non alcoholic steatohepatitis a precursor for hepatocellular carcinoma development
    2014
    Jiang, Chun-Meng; Pu, Chun-Wen; Hou, Ya-Hui; Chen, Zhe; Alanazy, Mohammed; Hebbard, Lionel (2014) 'N. ...
    Journal Publication ResearchOnline@JCU
    Synergistic effects of IAP inhibitor LCL161 and paclitaxel on hepatocellular carcinoma cells
    2014
    Tian, Aiping; Wilson, George S.; Lie, Stefanus; Wu, Guang; Hu, Zenan; Hebbard, Lionel; Duan, Wei; Ge...
    Journal Publication ResearchOnline@JCU
    Experimental nonalcoholic steatohepatitis compromises ureagenesis, an essential hepatic metabolic function
    2014
    Thomsen, Karen Louise; Grønbæk, Henning; Glavind, Emilie; Hebbard, Lionel; Jessen, Niels; Clouston, ...
    Journal Publication ResearchOnline@JCU
    Non-alcoholic steatohepatitis weakens the acute phase response to endotoxin in rats
    2014
    Thomsen, Karen L.; Hebbard, Lionel; Glavind, Emilie; Clouston, Andrew; Vilstrup, Hendrik; George, Ja...
    Journal Publication ResearchOnline@JCU
    Embelin reduces colitis-associated tumorigenesis through limiting IL-6/STAT3 signaling
    2014
    Dai, Yun; Jiao, Hongmei; Teng, Guigen; Wang, Weihong; Zhang, Rongxin; Wang, Yunhong; Hebbard, Lionel...
    Journal Publication ResearchOnline@JCU
    Multifaceted roles of adiponectin in cancer
    2014
    Hebbard, Lionel; Ranscht, Barbara (2014) 'Multifaceted roles of adiponectin in cancer'. Best practice & research Clinical endocrinology & metabo, 28 (1):59-69. [DOI] ...
    Journal Publication ResearchOnline@JCU
    ROCK1 inhibition promotes the self-renewal of a novel mouse mammary cancer stem cell
    2013
    Castro, David J.; Maurer, Jochen; Hebbard, Lionel; Oshima, Robert G. (2013) 'ROCK1 inhibition promot. Stem Cell, 31 (1):12-22. [DOI ...
    Journal Publication ResearchOnline@JCU
    Tumoricidal effects of the JAK inhibitor Ruxolitinib (INC424) on hepatocellular carcinoma in vitro
    2013
    Wilson, George S.; Tian, Aiping; Hebbard, Lionel; Duan, Wei; George, Jacob; Li, Xun; Qiao, Liang (20...
    Journal Publication ResearchOnline@JCU
    Classical and innovative insulin sensitizing drugs for the prevention and treatment of NAFLD
    2013
    Carulli, Lucia; Maurantonio, Mauro; Hebbard, Lionel; Baldelli, Enrica; Loria, Paola; George, Jacob (...
    Journal Publication ResearchOnline@JCU
    Hepatic fat loss in advanced nonalcoholic steatohepatitis: are alterations in serum adiponectin the cause
    2013
    van der Poorten, David; Samer, Caroline F.; Ramezani-Moghadam, Mehdi; Coulter, Sally; Kacevska, Mari...
    Journal Publication ResearchOnline@JCU
    Role of adiponectin and its receptors in cancer
    2012
    Obeid, Stephanie; Hebbard, Lionel (2012) 'Role of adiponectin and its receptors in cancer'. Cancer biology & medicine, 9 (4):213-220. [DOI] ...
    Journal Publication ResearchOnline@JCU
    Control of mammary tumor differentiation by SKI-606 (bosutinib)
    2011
    Hebbard, L.; Cecena, G.; Golas, J.; Sawada, J.; Ellies, L.G.; Charbono, A.; Williams, R.; Jimenez, R...
    Journal Publication ResearchOnline@JCU
    Animal models of nonalcoholic fatty liver disease
    2011
    Hebbard, Lionel; George, Jacob (2011) 'Animal models of nonalcoholic fatty liver disease'. Nature reviews. Gastroenterology & hepatology, 8 :35-44. [DOI] ...
    Journal Publication ResearchOnline@JCU
    Maternal embryonic leucine zipper kinase is upregulated and required in mammary tumor-initiating cells in vivo
    2010
    Hebbard, Lionel W.; Maurer, Jochen; Miller, Amber; Lesperance, Jacqueline; Hassell, John; Oshima, Ro...
    Journal Publication ResearchOnline@JCU
    Hepatitis C virus induces the cannabinoid receptor 1
    2010
    van der Poorten, David; Shahidi, Mahsa; Tay, Enoch; Sesha, Jayshree; Tran, Kayla; McLeod, Duncan; Mi...
    Journal Publication Open Access ResearchOnline@JCU
    Adiponectin deficiency limits tumor vascularization in the MMTV-PyV-mT mouse model of mammary cancer
    2009
    Denzel, Martin S.; Hebbard, Lionel W.; Shostak, Gregory; Shapiro, Lawrence; Cardiff, Robert D.; Rans...
    Journal Publication ResearchOnline@JCU
    T-cadherin supports angiogenesis and adiponectin association with the vasculature in a mouse mammary tumor model
    2008
    Hebbard, Lionel W.; Garlatti, Michèle; Young, Lawrence J.T.; Cardiff, Robert D.; Oshima, Robert G.; ...
    Journal Publication ResearchOnline@JCU
    Angiogenic acceleration of Neu induced mammary tumor progression and metastasis
    2004
    Oshima, Robert G.; Lesperance, Jacqueline; Munoz, Varinia; Hebbard, Lionel; Ranscht, Barbara; Sharan...
    Journal Publication ResearchOnline@JCU
    CD44 expression and regulation during mammary gland development and function
    2000
    Hebbard, Lionel; Steffen, Anja; Zawadzki, Volker; Fieber, Christina; Howells, Norma; Moll, Jürgen; P...
    Journal Publication ResearchOnline@JCU
    Increased expression of H/T-cadherin in tumor-penetrating blood vessels
    2000
    Wyder, Lorenza; Vitaliti, Alessandra; Schneider, Henriette; Hebbard, Lionel W.; Moritz, Dirk R.; Wit...
    Journal Publication ResearchOnline@JCU
    Adiponectin induces pro-infl ammatory cytokines in kupffer cells via the activation of mapk pathways
    2010
    Smith, B.W.; Hebbard, L.; George, J. (2010) 'Adiponectin induces pro-infl ammatory cytokines in kupf Journal of Gastroenterology and Hepatology, 25 (s3) :A6-A6. ...
    Journal Contribution ResearchOnline@JCU
    Animal models of hepatocellular carcinoma
    2012
    Walker, Sarah L.; George, Jacob; Hebbard, Lionel W. (2012) 'Animal models of hepatocellular carcinom In: Walker, Sarah L., George, Jacob, and...
    Role of angiogenesis in HCC development and therapy
    2012
    Hebbard, Lionel W. (2012) 'Role of angiogenesis in HCC development and therapy' In: Hebbard, Lionel W. (2012) Role of angiogenesis in HCC development an...