Robert Kinobe

Projects 4
Publications 51
Awards 6

Biography

Robert T. Kinobe, BVM (Hon), PhD, MANZCVS, DABVT, GCE.

Robert attained a Bachelor of Veterinary Medicine and Surgery with Honours at Makerere University (1996), following which he worked as a veterinarian and associate lecturer at the same university for three years. In 2004, Robert completed a PhD in Pharmacology and Toxicology at the University of Queensland, and this was followed by two postdoctoral research fellowships (2004-2008) with the Canadian Institute of Health, and the Heart and Stroke Foundation of Canada at the Department of Pharmacology and Toxicology, Queens University in Ontario Canada. In 2008, Robert was appointed to a teaching and research role at James Cook University. Robert is not in clinical practice presently, but he shares a passion for clinical pharmacology and toxicology and, undergraduate as well as postgraduate teaching. Robert is a qualified member and past president for the Veterinary Pharmacology Chapter of the Australian and New Zealand College of Veterinary Scientists, and a Diplomate of the American Board of Veterinary Toxicology.

Research

Research Interests

Domains of my expertise are experimental therapeutics and clinical toxicology, and antimicrobial resistance.

Projects

Teaching

Teaching Interests

Personal Teaching Philosophy:

Learning & teaching (L&T) processes are rewarding because application of acquired knowledge offers life changing, permanent experiences. I believe students learn best when:

     1. Educators set clear, concise learning objectives.

     2. Students appreciate the relevance; applications of skills and knowledge acquired in learning processes.

     3. Educators incorporate practical, real-life scenarios in the learning process

     4. Learning objectives are constructively aligned with tools of assessing outcomes.

     5. Students are engaged, feel supported and are provided feedback in learning processes.

     6. Educators are enthusiastic; reflective on pedagogical approaches with genuine interest to improve.


Research Advisor Accreditation

Advisor Type

Mentor

Research Advisor Accreditation

Role

Chair; Independent Academic


Activities

Education

Media

Associations

Awards

Employment

Output

Otto, John Roger; Pewan, Shedrach Benjamin; Edmunds, Richard Crawford; Mwangi, Felista Waithira; Kinobe, Robert Tumwesigye; Adegboye, Oyelola Abdulwasiu; Malau-Aduli, Aduli Enoch Othniel (2023) 'Differential expressions of FASN, SCD, and FABP4 genes in the ribeye muscle of omega-3 oil-supplemented Tattykeel Australian White lambs'. BMC Genomics, 24 . [DOI]
Journal Publication Open Access ResearchOnline@JCU
Foyle, Leo; Burnett, Matthew; Creaser, Abbey; Hens, Rachel; Keough, Julia; Madin, Lauren; Price, Ruby; Smith, Hayley; Stone, Samuel; Kinobe, Robert T. (2023) 'Prevalence and distribution of antimicrobial resistance in effluent wastewater from animal slaughter facilities: A systematic review'. Environmental Pollution, 318 . [DOI]
Journal Publication Open Access ResearchOnline@JCU
Mwangi, Felista W.; Suybeng, Benedicte; Gardiner, Christopher P.; Kinobe, Robert; Charmley, Edward; Malau-Aduli, Bunmi S.; Malau-Aduli, Aduli E.O. (2022) 'Effect of incremental proportions of Desmanthus spp. in isonitrogenous forage diets on growth performance, rumen fermentation and plasma metabolites of pen-fed growing Brahman, Charbray and Droughtmaster crossbred beef steers'. PLoS ONE, 17 (1). [DOI]
Journal Publication Open Access ResearchOnline@JCU
Phie, James; Thanigaimani, Shivshankar; Huynh, Pacific; Anbalagan, Raghuveeran; Moran, Corey S.; Kinobe, Robert; Moxon, Joseph; Field, Matt A.; Krishna, Smriti M.; Golledge, Jonathan (2022) 'Colchicine Does Not Reduce Abdominal Aortic Aneurysm Growth in a Mouse Model'. Cardiovascular Therapeutics, 2022 . [DOI]
Journal Publication Open Access ResearchOnline@JCU
Mwangi, Felista Waithira; Savage, Darryl; Gardiner, Christopher Peter; Charmley, Edward; Malau-Aduli, Bunmi Sherifat; Kinobe, Robert Tumwesigye; Malau-Aduli, Aduli Enoch Othniel (2022) 'Feedlot growth performance and carcass characteristics of steers backgrounded on buffel grass or buffel–Desmanthus mixed pastures'. Frontiers in Veterinary Science, 9 . [DOI]
Journal Publication Open Access ResearchOnline@JCU
Pewan, Shedrach Benjamin; Otto, John Roger; Kinobe, Robert Tumwesigye; Adegboye, Oyelola Abdulwasiu; Malau-Aduli, Aduli Enoch Othniel (2022) 'Fortification of diets with omega-3 long-chain polyunsaturated fatty acids enhances feedlot performance, intramuscular fat content, fat melting point, and carcass characteristics of Tattykeel Australian White MARGRA lambs'. Frontiers in Veterinary Science, 9 . [DOI]
Journal Publication Open Access ResearchOnline@JCU
Mwangi, Felista W.; Pewan, Shedrach B.; Otto, John R.; Adegboye, Oyelola A.; Charmley, Edward; Gardiner, Christopher P.; Malau-Aduli, Bunmi S.; Kinobe, Robert T.; Malau-Aduli, Aduli E.O. (2022) 'Single nucleotide polymorphisms in the fatty acid binding protein 4, fatty acid synthase and stearoyl-CoA desaturase genes influence carcass characteristics of tropical crossbred beef steers'. Agriculture, 12 (8). [DOI]
Journal Publication Open Access ResearchOnline@JCU
Mwangi, Felista W.; Charmley, Edward; Adegboye, Oyelola A.; Gardiner, Christopher P.; Malau-Aduli, Bunmi S.; Kinobe, Robert T.; Malau-Aduli, Aduli E.O. (2022) 'Chemical composition and in situ degradability of Desmanthus spp. forage harvested at different maturity stages'. Fermentation, 8 (8). [DOI]
Journal Publication Open Access ResearchOnline@JCU
Mwangi, Felista W.; Pewan, Shedrach B.; Otto, John R.; Adegboye, Oyelola A.; Charmley, Edward; Gardiner, Christopher P.; Malau-Aduli, Bunmi S.; Kinobe, Robert T.; Malau-Aduli, Aduli E.O. (2022) 'Towards sustainable sources of omega-3 long-chain polyunsaturated fatty acids in Northern Australian tropical crossbred beef steers through single nucleotide polymorphisms in lipogenic genes for meat eating quality'. Sustainability, 14 (14). [DOI]
Journal Publication Open Access ResearchOnline@JCU
Kinobe, Robert T.; Owens, Leigh (2021) 'A systematic review of experimental evidence for antiviral effects of ivermectin and an in silico analysis of ivermectin's possible mode of action against SARS-CoV-2'. Fundamental & Clinical Pharmacology, 35 (2):260-276. [DOI]
Journal Publication Open Access ResearchOnline@JCU
Mwangi, Felista W.; Gardiner, Christopher P.; Walker, Glen; Hall, Trevor J.; Malau-Aduli, Bunmi S.; Kinobe, Robert T.; Malau-Aduli, Aduli E.O. (2021) 'Growth performance and plasma metabolites of grazing beef cattle backgrounded on Buffel or Buffel-Desmanthus mixed pastures'. Animals, 11 (8). [DOI]
Journal Publication Open Access ResearchOnline@JCU
Mwangi, Felista W.; Blignaut, David J.C.; Charmley, Edward; Gardiner, Christopher P.; Malau-Aduli, Bunmi S.; Kinobe, Robert T.; Malau-Aduli, Aduli E.O. (2021) 'Lipid metabolism, carcass characteristics and Longissimus dorsi muscle fatty acid composition of tropical crossbred beef cattle in response to Desmanthus spp. forage backgrounding'. Metabolites, 11 (12). [DOI]
Journal Publication Open Access ResearchOnline@JCU
Drane, Kezia; Huerlimann, Roger; Power, Michelle; Whelan, Anna; Ariel, Ellen; Sheehan, Madoc; Kinobe, Robert (2021) 'Testudines as sentinels for monitoring the dissemination of antibiotic resistance in marine environments: an integrative review'. Antibiotics, 10 (7). [DOI]
Journal Publication Open Access ResearchOnline@JCU
Phie, J.; Krishna, S.M.; Kinobe, R.; Moxon, J.V.; Andrade-Lima, A.; Morton, S.K.; Lazzaroni, S.M.; Huynh, P.; Golledge, J. (2021) 'Effects of quercetin on exercise performance, physical activity and blood supply in a novel model of sustained hind-limb ischaemia'. BJS Open, 5 (1). [DOI]
Journal Publication Open Access ResearchOnline@JCU
Pewan, Shedrach Benjamin; Otto, John Roger; Huerlimann, Roger; Budd, Alyssa Marie; Mwangi, Felista Waithira; Edmunds, Richard Crawford; Holman, Benjamin William Behrens; Henry, Michelle Lauren Elizabeth; Kinobe, Robert Tumwesigye; Adegboye, Oyelola Abdulwasiu; Malau-Aduli, Aduli Enoch Othniel (2021) 'Next generation sequencing of single nucleotide polymorphic DNA-markers in selecting for intramuscular fat, fat melting point, omega-3 long-chain polyunsaturated fatty acids and meat eating quality in Tattykeel Australian White MARGRA lamb'. Foods, 10 (10). [DOI]
Journal Publication Open Access ResearchOnline@JCU
Krishnan, Anirudh; Chilton, Emily; Raman, Jaishankar; Saxena, Pankaj; McFarlane, Craig; Trollope, Alexandra F.; Kinobe, Robert; Chilton, Lisa (2021) 'Are interactions between epicardial adipose tissue, cardiac fibroblasts and cardiac myocytes instrumental in atrial fibrosis and atrial fibrillation?'. Cells, 10 (9). [DOI]
Journal Publication Open Access ResearchOnline@JCU
Pewan, Shedrach Benjamin; Otto, John Roger; Kinobe, Robert Tumwesigye; Adegboye, Oyelola Abdulwasiu; Malau-Aduli, Aduli Enoch Othniel (2021) 'Nutritional enhancement of health beneficial omega-3 long-chain polyunsaturated fatty acids in the muscle, liver, kidney, and heart of Tattykeel Australian White MARGRA lambs fed pellets fortified with omega-3 oil in a feedlot system'. Biology, 10 . [DOI]
Journal Publication Open Access ResearchOnline@JCU
Pewan, Shedrach; Otto, John Roger; Huerlimann, Roger; Budd, Alyssa Marie; Mwangi, Felista Waithira; Edmunds, Richard Crawford; Holman, Benjamin William Behrens; Henry, Michelle Lauren Elizabeth; Kinobe, Robert Tumwesigye; Adegboye, Oyelola Abdulwasiu; Malau-Aduli, Aduli Enoch Othniel (2020) 'Genetics of omega-3 long-chain polyunsaturated fatty acid metabolism and meat eating quality in Tattykeel Australian White lambs'. Genes, 11 (5). [DOI]
Journal Publication Open Access ResearchOnline@JCU
Pewan, Shedrach Benjamin; Otto, John Roger; Kinobe, Robert Tumwesigye; Adegboye, Oyelola Abdulwasiu; Malau-Aduli, Aduli Enoch Othniel (2020) 'MARGRA lamb eating quality and human health-promoting omega-3 long-chain polyunsaturated fatty acid profiles of Tattykeel Australian White sheep: linebreeding and gender effects'. Antioxidants, 9 (11). [DOI]
Journal Publication Open Access ResearchOnline@JCU
Picard, Jacqueline; Sutcliffe, Ruth; Kinobe, Robert T. (2020) 'Utilisation and evaluation of cooperative case-based teaching for integration of microbiology and pharmacology in veterinary education'. Health Professions Education, 6 (2):211-221. [DOI]
Journal Publication Open Access ResearchOnline@JCU
Kinobe, R.T.; Miyake, Y. (2020) 'Evaluating the anti-inflammatory and analgesic properties of maropitant: a systematic review and meta-analysis'. The Veterinary Journal, 100 . [DOI]
Journal Publication ResearchOnline@JCU
Mwangi, Felista W.; Charmley, Edward; Gardiner, Christopher P.; Malau-Aduli, Bunmi S.; Kinobe, Robert T.; Malau-Aduli, Aduli E.O. (2019) 'Diet and genetics influence beef cattle performance and meat quality characteristics'. Foods, 8 (12). [DOI]
Journal Publication Open Access ResearchOnline@JCU
Ahasan, Md. Shamim; Kinobe, Robert; Elliott, Lisa; Owens, Leigh; Scott, Jenni; Picard, Jacqueline; Huerlimann, Roger; Ariel, Ellen (2019) 'Bacteriophage versus antibiotic therapy on gut bacterial communities of juvenile green turtle, Chelonia mydas'. Environmental Microbiology, 21 (8):2871-2885. [DOI]
Journal Publication ResearchOnline@JCU
Hem, Nur-Aish; Phie, James; Chilton, Lisa; Kinobe, Robert (2019) 'A volume-pressure tail cuff method for hemodynamic parameters: comparison of restraint and light isoflurane anesthesia in normotensive male Lewis rats'. Journal of Pharmacological and Toxicological Methods, 100 . [DOI]
Journal Publication ResearchOnline@JCU
Phie, James; Moxon, Joseph V.; Krishna, Smriti M.; Kinobe, Robert; Morton, Susan K.; Golledge, Jonathan (2018) 'A diet enriched with tree nuts reduces severity of atherosclerosis but not abdominal aneurysm in angiotensin II-infused apolipoprotein E deficient mice'. Atherosclerosis, 277 :28-33. [DOI]
Journal Publication ResearchOnline@JCU
Li, Fangfei; Gorle, Anil K.; Ranson, Marie; Vine, Kara L.; Kinobe, Robert; Feterl, Marshall; Warner, Jeffrey M.; Keene, F. Richard; Collins, J. Grant; Day, Anthony I. (2017) 'Probing the pharmacokinetics of cucurbit[7, 8 and 10]uril: and a dinuclear ruthenium antimicrobial complex encapsulated in cucurbit[10]uril'. Organic and Biomolecular Chemistry, 15 (19):4172-4179. [DOI]
Journal Publication Open Access ResearchOnline@JCU
Phie, James; Krishna, Smriti M.; Moxon, Joseph V.; Omer, Safraz M.; Kinobe, Robert; Golledge, Jonathan (2017) 'Flavonols reduce aortic atherosclerosis lesion area in apolipoprotein E deficient mice: a systematic review and meta-analysis'. PLoS ONE, 12 (7):1-13. [DOI]
Journal Publication Open Access ResearchOnline@JCU
Ahasan, Md. Shamim; Picard, Jacqueline; Elliot, Lisa; Kinobe, Robert; Owens, Leigh; Ariel, Ellen (2017) 'Evidence of antibiotic resistance in Enterobacteriales isolated from green sea turtles, Chelonia mydas on the Great Barrier Reef'. Marine Pollution Bulletin, 120 :18-27. [DOI]
Journal Publication ResearchOnline@JCU
Kinobe, Robert T. (2016) 'Towards the elimination of excessive cobalt supplementation in racing horses: a pharmacological review'. Research in Veterinary Science, 104 :106-112. [DOI]
Journal Publication ResearchOnline@JCU
Yu, Hongyou; Moran, Corey S.; Trollope, Alexandra F.; Woodward, Lynn; Kinobe, Robert; Rush, Catherine M.; Golledge, Jonathan (2016) 'Angiopoietin-2 attenuates angiotensin II-induced aortic aneurysm and atherosclerosis in apolipoprotein E-deficient mice'. Scientific Reports, 6 :1-11. [DOI]
Journal Publication Open Access ResearchOnline@JCU
Gorle, Anil K.; Li, Xin; Primrose, Sebastian; Li, Fangfei; Feterl, Marshall; Kinobe, Robert T.; Heimann, Kirsten; Warner, Jeffrey M.; Keene, F. Richard; Collins, J. Grant (2016) 'Oligonuclear polypyridylruthenium(II) complexes: selectivity between bacteria and eukaryotic cells'. Journal of Antimicrobial Chemotherapy, 71 :1547-1555. [DOI]
Journal Publication ResearchOnline@JCU
Phie, James; Haleagrahara, Nagaraja; Newton, Patricia; Constantinoiu, Constantin; Sarnyai, Zoltan; Chilton, Lisa; Kinobe, Robert (2015) 'Prolonged subcutaneous administration of oxytocin accelerates angiotensin II-induced hypertension and renal damage in male rats'. PLoS ONE, 10 (9):1-19. [DOI]
Journal Publication Open Access ResearchOnline@JCU
Allwood, Melissa A.; Kinobe, Robert T.; Ballantyne, Laurel; Romanova, Nadya; Melo, Luis G.; Ward, Christopher A.; Brunt, Keith R.; Simpson, Jeremy A. (2014) 'Heme oxygenase-1 overexpression exacerbates heart failure with aging and pressure overload but is protective against isoproterenol-induced cardiomyopathy in mice'. Cardiovascular Pathology, 23 (4):231-237. [DOI]
Journal Publication ResearchOnline@JCU
Nguyen, Kim Y.; Sakuna, Kitikarn; Kinobe, Robert; Owens, Leigh (2014) 'Ivermectin blocks the nuclear location signal of parvoviruses in crayfish, Cherax quadricarinatus'. Aquaculture, 420-421 :288-294. [DOI]
Journal Publication ResearchOnline@JCU
Dam, Van P.; Scott, Jennifer L.; Ross, Anthony; Kinobe, Robert T. (2012) 'Inhibition of cystathionine gamma-lyase and the biosynthesis of endogenous hydrogen sulphide ameliorates gentamicin-induced nephrotoxicity'. European Journal of Pharmacology, 685 (1-3):165-173. [DOI]
Journal Publication ResearchOnline@JCU
Vukomanovic, Dragic; McLaughlin, Brian; Rahman, Mona N.; Vlahakis, Jason Z.; Roman, Gheorghe; Dercho, Ryan A.; Kinobe, Robert; Hum, Maaike; Brien, James F.; Jia, Zongchao; Szarek, Walter A.; Nakatsu, Kanji (2010) 'Recombinant truncated and microsomal heme oxygenase-1 and -2: differential sensitivity to inhibitors'. Canadian Journal of Physiology and Pharmacology, 88 (4):480-486. [DOI]
Journal Publication ResearchOnline@JCU
Brunt, Keith R.; Tsuji, Mathew R.; Lai, Joyce H.; Kinobe, Robert T.; Durante, William; Claycomb, William C.; Ward, Christopher A.; Melo, Luis G. (2009) 'Heme oxygenase-1 inhibits pro-oxidant induced hypertrophy in HL-1 cardiomyocytes'. Experimental Biology and Medicine, 234 (5):582-594. [DOI]
Journal Publication ResearchOnline@JCU
Kinobe, Robert T.; Dercho, Ryan A.; Nakatsu, Kanji (2008) 'Inhibitors of the heme oxygenase-carbon monoxide system: on the doorstep of the clinic?'. Canadian Journal of Physiology and Pharmacology, 86 (9):577-599. [DOI]
Journal Publication ResearchOnline@JCU
Roman, Gheorghe; Riley, John; Vlahakis, Jason; Kinobe, Robert; Brien, James; Nakatsu, Kanji; Szarek, Walter (2007) 'Heme oxygenase inhibition by 2-oxy-substituted 1-(1H-imidazol-1-yl)-4-phenylbutanes: Effect of halogen substitution in the phenyl ring'. Bioorganic & Medicinal Chemistry, 15 :3225-3234. [DOI]
Journal Publication ResearchOnline@JCU
Knobe, Robert T.; Ji, Yanbin; Vlahakis, Jason Z.; Motterlini, Roberto; Brien, James F.; Szarek, Walter A.; Nakatsu, Kanji (2007) 'Effectiveness of novel imidazole-dioxolane heme oxygenase inhibitors in renal proximal tubule epithelial cells'. Journal of Pharmacology and Experimental Therapeutics, 323 (3):763-770. [DOI]
Journal Publication ResearchOnline@JCU
Liu, Xiaoli; Simpson, Jeremy; Brunt, Keith; Ward, Christopher; Hall, Sean; Kinobe, Robert; Barrette, Valerie; Tse, M. Yat; Pang, Stephen; Pachori,, Alok; Dzau, Victor; Ogunyankin,, Kofo; Melo, Luis (2007) 'Preemptive heme oxygenase-1 gene delivery reveals reduced mortality and preservation of left ventricular function 1 yr after acute myocardial infarction'. American Journal of Physiology-Heart and Circulatory Physiology, 293 :48-59. [DOI]
Journal Publication ResearchOnline@JCU
Eyles, Darryl W.; Smith, Steven; Kinobe, Robert; Hewison, Martin; Mcgrath, John (2005) 'Distribution of the vitamin D receptor and 1α-hydroxylase in human brain'. Journal of Chemical Neuroanatomy, 29 (1):21-30. [DOI]
Journal Publication ResearchOnline@JCU
Kinobe, Robert; Ji, Yanbin; Nakatsu, Kanji (2004) 'Peroxynitrite-mediated inactivation of heme oxygenases '. BMC Pharmacology, 4 :1-9. [DOI]
Journal Publication Open Access ResearchOnline@JCU
Drane, Kezia; Huerlimann, Roger; Power, Michelle; Ariel, Ellen; Sheehan, Madoc; Kinobe, Robert (2021) 'Using Green sea turtles (Chelonia mydas) as essential bio-indicators for monitoring antibiotic resistance in marine environments worldwide: a critical appraisal' FASEB Journal, 35 (S1) :03303-03303. [DOI]
Journal Contribution ResearchOnline@JCU
Kinobe, Robert; Hem, Nur-Aisha; Rudd, Donna; Kapoor, Ranjna; Chilton, Lisa (2021) 'Maintaining normal blood pressure in a renovascular stenosis model of hypertension in adult Lewis rats: putative physiological modulation of the renin-angiotensin system' FASEB Journal, 35 (S1) :01655-01655.
Journal Contribution ResearchOnline@JCU
Kinobe, Robert T.; Phie, James; Haleagrahara, Nagaraja; Chilton, Lisa (2016) 'Carbon monoxide releasing molecule-3 alleviates angiotensin II-induced hypertrophy and apoptosis by inhibiting oxidative and endoplasmic reticulum stress in H9c2 cardiomyocytes' FASEB Journal, 30 (1) . [DOI]
Journal Contribution ResearchOnline@JCU
Nakatsu, Kanji; Szarek, Walter A.; Brien, James F.; Jia, Zongchao; Vlahakis, Jason Z.; Kinobe, Robert T.; Roman, Gheorghe; Rahman, Mona N.; McLaughlin, Brian E.; Vukomanovic, Dragic; Dercho , Ryan; Hum, Maaike (2012) 7th International Congress on Heme Oxygenases and Related Enzymes Creation of novel pharmacological tools in heme oxygenase research Edinburgh, UK, .
Conference Contribution Open Access ResearchOnline@JCU
Kinobe, Robert T.; Van , Dam P.; Scott, Jennifer L.; Hall, Christine; Blyth, Scott; Reilly, Laurie; Ross, Anthony (2011) Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists Inhibition of cystathionine-gamma-lyase and the biosynthesis of endogenous hydrogen sulphide ameliorates gentamicin-induced nephrotoxicity Perth, WA, Australia, .
Conference Contribution Open Access ResearchOnline@JCU
Kinobe, Robert; Keller, Ninette (2011) Chapter of Veterinary Pharmacology, Science Week 2011 Principles of therapeutic drug monitoring: a case of drug-resistant epilepsy in a dog Gold Coast, Queensland, .
Conference Contribution Open Access ResearchOnline@JCU
Kinobe, Robert; Soong, Jonathan; Brien, James; Longo, Lawrence; Nakatsu, Kanji (2005) Pediatric Research Heme Oxygenase Activity in Fetal and Adult Ovine Tissue: Effects of High altitude-induced Long-term Hypoxemia Toronto, Canada, . [DOI]
Conference Contribution ResearchOnline@JCU
Kinobe, Robert; Dickinson, Ronald; Gillam, Elizabeth (2001) Toxicology Deletion of glutathione S-transferase theta-1 (GSTT1) and anticonvulsant (ACD)—induced hypersensitivity syndrome Brisbane, Australia, . [DOI]
Conference Contribution Open Access ResearchOnline@JCU