Principles of therapeutic drug monitoring: a case of drug-resistant epilepsy in a dog
Conference Contribution ResearchOnline@JCUAbstract
Drug analysis for purposes of monitoring therapeutic outcomes is not a common practice in veterinary medicine but may be extremely valuable in many circumstances including; clinical cases in which there is a poor correlation between dose and drug plasma concentration, and therapeutic or toxic effects, confirmation of drug-induced toxicity for medications with very low therapeutic indices, assessment of compliance with the drug administration and assessing the occurrence of drug-drug interactions. Therapeutic drug monitoring may also be indicated for patients with altered physiological states such as renal, thyroid and hepatic disease, and electrolyte imbalances. In this article, a clinical case of canine idiopathic epilepsy with an apparent resistance to antiepileptic drug therapy is used to illustrate some of the basic principles of therapeutic drug monitoring (TMD).
Journal
N/A
Publication Name
Chapter of Veterinary Pharmacology, Science Week 2011
Volume
N/A
ISBN/ISSN
N/A
Edition
N/A
Issue
N/A
Pages Count
6
Location
Gold Coast, Queensland
Publisher
Australian College of Veterinary Scientists, Chapter of Veterinary Pharmacology
Publisher Url
N/A
Publisher Location
N/A
Publish Date
N/A
Url
N/A
Date
N/A
EISSN
N/A
DOI
N/A