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Projects

1

Publications

40

Awards

0


Contact Details

Senior Lecturer

Biography

Dr Craig McFarlane is a research scientist and senior lecturer in the Department of Molecular and Cell Biology. He completed his PhD in 2007 in New Zealand and has undertaken postdoctoral studies at AgResearch in New Zealand and Nanyang Technological University, Singapore. As a principal investigator he established a research group in the Singapore Institute for Clinical Sciences, an Agency for Science, Technology and Research (A*STAR) institute. He has published his research in several highly ranked international journals, including: Nature Communications, PLOS Biology, Diabetes, Journal of Biological Chemistry, Cell Research and International Journal of Obesity. Dr McFarlane moved to Australia in 2017 to take up his new role in James Cook University and his current research focuses on understanding mechanisms that regulate skeletal muscle growth and repair and the role of skeletal muscle function in regulating glucose and lipid metabolism during obesity, insulin resistance and metabolic syndrome.

Specialities

Dr McFarlane has extensive experience in utilising mouse models and in vitro cell culture model systems to study and identify mechanisms linked to muscle stem cell function and muscle wasting associated with chronic diseases. In addition, he has undertaken studies to identify genetic and epigenetic pathways that transduce the adverse effect of high caloric diet nutrition on the development of insulin resistance in skeletal muscle. He has also identified mechanisms through which skeletal muscle can influence the function of other tissues in the body, including white adipose tissue, to regulate whole body energy expenditure and utilisation.

Research

Research Interests

Cultivated meat (clean meat)

Cellular agriculture

Building a better future with biology

Browning of white adipose tissue

Insulin resistance

Molecular mechanisms associated with type 2 diabetes

Molecular mechanisms that regulate postnatal myogenesis

Skeketal muscle wasting and cachexia

Skeletal muscle secreted growth factors

Muscle stem cells

Skeletal muscle regeneration

Glucose tolerance

Projects

Teaching

Research Advisor Accreditation
Advisor Type

Mentor

Research Advisor Accreditation
Role

Chair; Independent Academic


Taught Modules
Current JCU Research Students
Sarcopenia in patient undergoing cardiac surgery
Doctor of Philosophy (Health)
Developing a new treatment regime for hepatocellular carcinoma
Doctor of Philosophy (Medical, Molecular and Veterinary Sciences)
Completed JCU Research Students
The role of T-cadherin in regulating skeletal muscle myogenesis
Doctor of Philosophy (Medical and Molecular Sciences)- 2024
Current Honours and External Research Students
Characterisation of Barramundi primary muscle cells
HONOURS- 2024
Completed Honours and External Research Students
The Role of T-cadherin in Skeletal Muscle
HONOURS

Activities

Associations

Output

McFarlane, Craig; Sharma, Mridula; Kambadur, Ravi (2010) Role of myostatin in skeletal muscle growth. London, UK: [DOI] ...
Other Publication ResearchOnline@JCU
Harkus, Uasim; Wankell, Miriam; Palamuthusingam, Pranavan; McFarlane, Craig McFarlane; Hebbard, Lion...
Journal Publication ResearchOnline@JCU
Leow, Melvin Khee Shing; Dogra, Shaillay; Ge, Xiaojia; Chuah, Khoon Leong; Liew, Huiling; Loke, Kelv...
Journal Publication ResearchOnline@JCU
Taylor, Lauren; Wankell, Miriam; Saxena, Pankaj; McFarlane, Craig McFarlane; Hebbard, Lionel (2021) ...
Journal Publication ResearchOnline@JCU
Sun, Eun Jin; Wankell, Miriam; Palamuthusingam, Pranavan; McFarlane, Craig; Hebbard, Lionel (2021) '....
Journal Publication ResearchOnline@JCU
Antoun, Elie; Migliavacca, Eugenia; Garratt, Emma S.; Barton, Sheila J.; Titcombe, Phil; Westbury, L...
Journal Publication ResearchOnline@JCU
Krishnan, Anirudh; Chilton, Emily; Raman, Jaishankar; Saxena, Pankaj; McFarlane, Craig; Trollope, Al...
Journal Publication ResearchOnline@JCU
Manfredi, Leandro Henrique; Ang, Joshur; Peker, Nesibe; Dagda, Ruben K.; McFarlane, Craig McFarlane ...
Journal Publication ResearchOnline@JCU
Migliavacca, Eugenia; Tay, Stacey K.H.; Patel, Harnish P.; Sonntag, Tanja; Civiletto, Gabriele; McFa...
Journal Publication ResearchOnline@JCU
Peker, Nesibe; Donipadi, Vinay; Sharma, Mridula; McFarlane, Craig; Kambadur, Ravi (2018) 'Loss of Pa. 315 (2):...
Journal Publication ResearchOnline@JCU
Julien, Sofi G.; Kim, Sun-Yee; Brunmeir, Reinhard; Sinnakannu, Joanna R.; Ge, Xiaojia; Li, Hongyu; M...
Journal Publication ResearchOnline@JCU
Musarrat, Maisha Reza; Subramaniyam, Nathiya; Sim, Chu Ming; Ge, Xiaojia; Sathiakumar, Durgalakshmi;...
Journal Publication ResearchOnline@JCU
Ge, X.; Sathiakumar, D.; Lua, B.J.G.; Kukreti, H.; Lee, M.; McFarlane, C. (2017) 'Myostatin signals . International Jo, 41 :137-148. ...
Journal Publication ResearchOnline@JCU
Reza, Musarrat Maisha; Sim, Chu Ming; Subramaniyam, Nathiya; Ge, Xiaojia; Sharma, Mridula; Kambadur,...
Journal Publication ResearchOnline@JCU
Leow, Shi Chi; Poschmann, Jeremie; Too, Peh Gek; Yin, Juan; Joseph, Roy; McFarlane, Craig; Dogra, Sh...
Journal Publication ResearchOnline@JCU
Sharma, Mridula; McFarlane, Craig; Kambador, Ravi; Kukreti, Himani; Bonala, Sabeera; Srinivasan, Shr...
Journal Publication ResearchOnline@JCU
Chandrashekar, Preeti; Manickam, Ravikumar; Ge, Xiaojia; Bonala, Sabeera; McFarlane, Craig; Sharma, ...
Journal Publication ResearchOnline@JCU
Khoo, Chin Meng; Leow, Melvin Khee-Shing; Sadananthan, Suresh Arnand; Lim, Radiance; Venkataraman, K...
Journal Publication ResearchOnline@JCU
Shenoy P., Sudheer; Bose, Bipasha; Sharma, Mridula; McFarlane, Craig; Kambadur, Ravi (2014) 'Lack of. 115 (...
Journal Publication ResearchOnline@JCU
McFarlane, Craig; Vajjala, Anuradha; Arigela, Harikumar; Lokireddy, Sudarsanareddy; Ge, Xiaojia; Bon...
Journal Publication ResearchOnline@JCU
Sriram, Sandhya; Subramanian, Subha; Juvvuna, Prasanna Kumar; Ge, Xiaojia; Lokireddy, Sudarsanareddy...
Journal Publication ResearchOnline@JCU
Sharma, Mridula; Juvvuna, Prasanna Kumar; Kukreti, Himani; McFarlane, Craig (2014) 'Mega roles of mi. Frontiers in P, 5 . [DOI] ...
Journal Publication ResearchOnline@JCU
Kukreti, Himani; Amuthavalli, Kottaiswamy; Harikumar, Arigela; Sathiyamoorthy, Sushmitha; Feng, Peng...
Journal Publication ResearchOnline@JCU
Lokireddy, Sudarsanareddy; Wijesoma, Isuru Wijerupage; Sze, Siu Kwan; McFarlane, Craig; Kambadur, Ra...
Journal Publication ResearchOnline@JCU
Zhang, C.; McFarlane, C.; Lokireddy, S.; Masuda, S.; Ge, X.; Gluckman, P.D.; Sharma, M.; Kambadur, R...
Journal Publication ResearchOnline@JCU
Zhang, Chen; Tan, Chek Kun; McFarlane, Craig; Sharma, Mridula; Tan, Nguan Soon; Kambadur, Ravi (2012...
Journal Publication ResearchOnline@JCU
Ge, Xiaojia; Vajjala, Anuradha; McFarlane, Craig; Wahli, Walter; Sharma, Mridula; Kambadur, Ravi (20...
Journal Publication ResearchOnline@JCU
Lokireddy, Sudarsanareddy; Mouly, Vincent; Butler-Browne, Gillian; Gluckman, Peter D.; Sharma, Mridu...
Journal Publication ResearchOnline@JCU
Zhang, C.; McFarlane, C.; Lokireddy, S.; Bonala, S.; Ge, X.; Masuda, S.; Gluckman, P.D.; Sharma, M.;...
Journal Publication ResearchOnline@JCU
Ge, Xiaojia; McFarlane, Craig; Vajjala, Anuradha; Lokireddy, Sudarsanareddy; Ng, Zhi Hui; Tan, Chek ...
Journal Publication ResearchOnline@JCU
McFarlane, Craig; Hui, Gu Zi; Amanda, Wong Zhi Wei; Lau, Hiu Yeung; Lokireddy, Sudarsanareddy; Ge, X...
Journal Publication ResearchOnline@JCU
Sriram, Sandhya; Subramanian, Subha; Sathiakumar, Durga; Venkatesh, Rithika; Salerno, Monica S.; McF...
Journal Publication ResearchOnline@JCU
McFarlane, Craig; Hennebry, Alex; Thomas, Mark; Plummer, Erin; Ling, Nicholas; Sharma, Mridula; Kamb...
Journal Publication ResearchOnline@JCU
McFarlane, Craig McFarlane; Plummer, Erin; Thomas, Mark; Hennebry, Alex; Ashby, Murray; Ling, Nichol...
Journal Publication ResearchOnline@JCU
McFarlane, Craig; Langley, Brett; Thomas, Mark; Hennebry, Alex; Plummer, Erin; Nicholas, Gina; McMah...
Journal Publication ResearchOnline@JCU
Langley, Brett; Thomas, Mark; McFarlane, Craig; Gilmour, Stewart; Sharma, Mridula; Kambadur, Ravi (2...
Journal Publication ResearchOnline@JCU
Leow, Melvin Khee Shing; Ang, Joshur; Bi, Xinyan; Koh, Ee Tzun; McFarlane, Craig (2023) 'Alterations AACE Clini, 9 (5) :1...
Journal Contribution ResearchOnline@JCU
Ge, Xiaojia; Leow, Shi Chi; Sathiakumar, Durgalakshmi; Stünkel, Walter; Shabbir, Asim; So, Jimmy; Lo...
Journal Contribution ResearchOnline@JCU
Sharma, Mridula; Kambadur, Ravi; Sriram, Sandhya; Lokireddy, Sudarsanareddy; McFarlane, Craig (2014)...
Journal Contribution ResearchOnline@JCU
McFarlane, Craig; Sharma, Mridula; Kambadur, Ravi (2008) 'Myostatin is a procachectic growth factor 11 (4) :422-427. [DOI] ...
Journal Contribution ResearchOnline@JCU