Cell adhesion an important determinant of myogenesis and satellite cell activity

Journal Publication ResearchOnline@JCU
Taylor, Lauren;Wankell, Miriam;Saxena, Pankaj;McFarlane, Craig McFarlane;Hebbard, Lionel
Craig McFarlaneLionel Hebbard
Abstract

Skeletal muscles represent a complex and highly organised tissue responsible for all voluntary body movements. Developed through an intricate and tightly controlled process known as myogenesis, muscles form early in development and are maintained throughout life. Due to the constant stresses that muscles are subjected to, skeletal muscles maintain a complex course of regeneration to both replace and repair damaged myofibers and to form new functional myofibers. This process, made possible by a pool of resident muscle stem cells, termed satellite cells, and controlled by an array of transcription factors, is additionally reliant on a diverse range of cell adhesion molecules and the numerous signaling cascades that they initiate. This article will review the literature surrounding adhesion molecules and their roles in skeletal muscle myogenesis and repair.

Journal

N/A

Publication Name

N/A

Volume

1869

ISBN/ISSN

0167-4889

Edition

N/A

Issue

2

Pages Count

8

Location

N/A

Publisher

Elsevier

Publisher Url

N/A

Publisher Location

N/A

Publish Date

N/A

Url

N/A

Date

N/A

EISSN

N/A

DOI

10.1016/j.bbamcr.2021.119170