Australian Institute of Tropical Health & Medicine
Darren Pickering
- Senior Research Officer
- darren.pickering@jcu.edu.au
Stephan Karl
- Principal Research Fellow, Malaria and Vector Biology
- stephan.karl@jcu.edu.au
Melanie Koinari
- Research Officer
- melanie.koinari@jcu.edu.au
Denise Doolan
- Adjunct Professor
- denise.doolan@jcu.edu.au
Advancing Immune Discovery in Northern Australia with Spectral Flow Cytometry
JCU respectfully seeks support from the Ian Potter Foundation to purchase the Cytek Aurora Spectral Flow Cytometer. This instrument is used for identifying, and conducting detailed analyses of single cells. The Cytek Aurora will replace JCU’s current, outdated flow cytometry instrument in Cairns: the FACSCanto II 3-laser eight-colour Flow Cytometer. This equipment is 15 years old and no longer meets JCU’s needs.
Combating antibiotic-resistant infections using a health system approach (Old ID 23169)
The march of antibiotic resistance across the globe is leading to what many are calling the “post-antibiotic era”. This puts a massive, preventable burden both on patients and Queensland’s health system, costing millions of dollars each year. North Queensland is geographically vulnerable to emerging infectious diseases, located at the tropical Indo- Pacific gateway, with the highest rates of resistant tuberculosis, and incursions of dengue virus, for example. This project will generate an evidence base for cost and risks of infectious diseases in North Queensland; by linking several health system datasets, to synthesise prospective and retrospective cohorts. Professorial and Infectious Diseases Units at TTH are co-investigators of the project investing personnel to perform the research. Further, TTH infection control and executive policy-makers are the target end-user for translation of the research.
Macrobiome Therapeutics Research Contract
This project involved Macrobiome contracting JCU to undertake R&D activities relating to the clinical development of two hookworm-derived proteins (MBT001 and MBT002) that are candidate drugs for the treatment of inflammatory bowel disease. The aim of this project is to acquire further data on the drug mechanism(s) of action (MOA) and efficacy is various pre-clinical models of colitis, as well as bioinformatically linking the MOA with the appropriate human disease population to target in future clinical trials.
Macrobiome Therapeutics Research Contract
This project involved Macrobiome contracting JCU to undertake R&D activities relating to the clinical development of two hookworm-derived proteins (MBT001 and MBT002) that are candidate drugs for the treatment of inflammatory bowel disease. The aim of this project is to acquire further data on the drug mechanism(s) of action (MOA) and efficacy is various pre-clinical models of colitis, as well as bioinformatically linking the MOA with the appropriate human disease population to target in future clinical trials.
Centre of Research Excellence in Tuberculosis Control on both sides of our border. (Old ID 26555)
This is a capacity building project on tuberculosis research including clinical trials, genomics, immunology and modelling for policy decision support. It involves researchers at USyd, U Melb, Monash and JCU. My role is in mathematical modelling of tuberculosis and this work will provide a network of tuberculosis researchers with which to collaborate.
The spatio-temporal epidemic dynamics of COVID-19 outbreak in Africa
- 2020
- Cambridge University Press
- Researchers:Adeshina Adekunle
Performance of cardiovascular risk prediction equations in Indigenous Australians
- 2020
- BMJ Publishing
- Researchers:Robyn McDermott
The NK cell granule protein NKG7 regulates cytotoxic granule exocytosis and inflammation
- 2020
- Nature Publishing Group
- Researchers:Alan BaxterAlex LoukasNorelle Daly
Helminth coinfection and COVID-19: an alternate hypothesis
- 2020
- Public Library of Science
- Researchers:Doris PiercePaul GiacominAlex LoukasRobyn McDermott
ampir: an R package for fast genome-wide prediction of antimicrobial peptides
- 2020
- Oxford University Press
- Researchers:David MillerJan StrugnellNorelle DalyIra Cooke
Modeling the potential of wAu-Wolbachia strain invasion in mosquitoes to control Aedes-borne arboviral infections
- 2020
- Nature Publishing Group
- Researchers:Adeshina AdekunleMichael MeehanEmma McBryde
Modeling drug-resistant tuberculosis amplification rates and intervention strategies in Bangladesh
- 2020
- Public Library of Science
- Researchers:Michael MeehanEmma McBrydeAdeshina Adekunle
Title:
Small fish, small pond: The reality of biomedical early career research in regional Australia
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01 Jan 2001
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01 Jan 2024