Projects 1
Publications 4
Awards 0

Biography

Dr Wu joined James Cook University in July 2022 as an Early Career Postdoctoral Researcher in A/Prof. Ulf Schmitz's team. Additionally, he holds the position of Lecturer in Computational Biology and Bioinformatics in the College of Science and Engineering.

Thaddeus earned his PhD in Applied Mathematics from Monash University in March 2022. He conducts research in mathematical and computational biology, utilising his experience in mathematical modelling, algorithm development, and statistical analysis to study the mechanisms of cell fate determination.

Currently, Thaddeus is focused on developing a novel mathematical framework to describe how mechanisms of alternative splicing and isoform expression at the single-cell level regulate cell fate determination.

Available HDR Student Projects

Research

Research Interests

Mathematical Modelling

Mathematical and Computational Biology

Systems Biology

Stochastic Modelling

Dynamical Systems

Projects

Teaching

Research Advisor Accreditation

Advisor Type

Secondary


Taught Modules

Current JCU Research Students

A Machine Learning model for cell type classification based on single-cell isoform expression data
Master of Philosophy (Medical, Molecular and Veterinary Sciences)

Activities

Associations

Languages

Employment

Output

Wu, Siyuan; Schmitz, Ulf (2023) 'Single-cell and long-read sequencing to enhance modelling of splicing and cell-fate determination'. Computational and Structural Biotechnology Journal, 21 :2373-2380. [DOI]
Journal Publication Open Access ResearchOnline@JCU
Wu, Siyuan; Zhou, Tianshou; Tian, Tianhai (2022) 'A robust method for designing multistable systems by embedding bistable subsystems'. npj Systems Biology and Applications, 8 (10). [DOI]
Journal Publication Open Access ResearchOnline@JCU
Wu, Siyuan; Cui, Tiangang; Zhang, Xinan; Tian, Tianhai (2020) 'A non-linear reverse-engineering method for inferring genetic regulatory networks'. PeerJ, 8 . [DOI]
Journal Publication Open Access ResearchOnline@JCU
Wu, Siyuan; Cui, Tiangang; Tian, Tianhai (2019) 2018 IEEE International Conference on Bioinformatics and Biomedicine (BIBM) Mathematical Modelling of Genetic Network for Regulating the Fate Determination of Hematopoietic Stem Cells Madrid, Spain, [DOI]
Conference Publication ResearchOnline@JCU