Jodie Morris
- jodie.morris1@jcu.edu.au
https://orcid.org/0000-0002-4795-5539- Research Fellow
- Medicine
Projects
2
Publications
28
Awards
0
Biography
Dr Morris is a biomedical scientist and Research Fellow within the Heart, Trauma and Sepsis Research Laboratory. Her research efforts are focused on characterising the complex cellular and molecular mechanisms underlying recovery versus immune-mediated pathologies after surgery, trauma and infection, and the effect of sex and co-morbidities on these processes.
Research
Projects
Output
Morris, Jodie; Letson, Hayley; Dobson, Geoffrey (2024) 'Safety evaluation of adenosine, lidocaine and magnesium
(ALM) intranasal therapy toward human nasal epithelial
cells in vitro'. Basic and Clinical Pharmacology and Toxicology, 135 (1):98-108. [DOI]
Pathophysiology of severe burn injuries: new therapeutic opportunities from a systems perspective
2024
Dobson, Geoffrey P.; Morris, Jodie L.; Letson, Hayley L. (2024) 'Pathophysiology of severe burn injuries: new therapeutic opportunities from a systems perspective'. Journal of Burn Care and Research, 45 (4):1041-1050. [DOI]
Morris, Jodie L.; Letson, Hayley L.; McEwen, Peter C.; Dobson, Geoffrey P. (2024) 'Adenosine, lidocaine, and magnesium therapy augments joint tissue healing following experimental anterior cruciate ligament rupture and reconstruction'. Bone & Joint Research, 13 (6):279-293. [DOI]
Dobson, Geoffrey; Letson, Hayley; Morris, Jodie (2024) 'Revolution in sepsis: a symptoms-based to a systems-based approach?'. Journal of Biomedical Science, 31 . [DOI]
Dobson, Geoffrey P.; Morris, Jodie L.; Letson, Hayley L. (2023) 'Adenosine, lidocaine and Mg2+ update: teaching old drugs new tricks'. Frontiers in Medicine, 10 . [DOI]
Morris, Jodie L.; McEwen, Peter C.; Letson, Hayley L.; Dobson, Geoffrey P. (2023) 'Adenosine, Lidocaine and Magnesium (ALM) therapy modulates early sex-specific inflammatory and immune responses following experimental anterior cruciate ligament rupture and reconstruction'. Translational Medicine Communications, 8 . [DOI]
Letson, Hayley; Morris, Jodie; Dobson, Geoffrey (2023) 'Changes in plasma alpha-1 acid glycoprotein following hemorrhagic trauma: Possible role in dose differences of ALM drug therapy in rat and pig resuscitation'. Pharmacology Research & Perspectives, 11 (5). [DOI]
Letson, Hayley L.; Biros, Erik; Morris, Jodie L.; Dobson, Geoffrey P. (2022) 'ALM fluid therapy shifts sympathetic hyperactivity to parasympathetic dominance in the rat model of non-compressible hemorrhagic shock'. Shock, 57 (2):264-273. [DOI]
Journal Publication
ResearchOnline@JCU
Morris, Jodie L.; Letson, Hayley L.; Biros, Erik; McEwen, Peter C.; Dobson, Geoffrey P. (2022) 'Female rats have a different healing phenotype than males after anterior cruciate ligament rupture with no intervention'. Frontiers in Medicine, 9 . [DOI]
Letson, Hayley L.; Morris, Jodie L.; Biros, Erik; Dobson, Geoffrey P. (2022) 'ALM induces cellular quiescence in the surgical margin 3 d following liver resection, hemorrhage, and shock'. Journal of Surgical Research, 275 :16-28. [DOI]
Journal Publication
ResearchOnline@JCU
Morris, Jodie; McEwen, Peter; Letson, Hayley; Dobson, Geoffrey (2022) 'Anterior Cruciate Ligament Reconstruction Surgery: Creating a Permissive Healing Phenotype in Military Personnel and Civilians for Faster Recovery'. Military Medicine, 187 (11-12):1310-1317. [DOI]
Dobson, Geoffrey P.; Morris, Jodie L.; Letson, Hayley L. (2022) 'Why are bleeding trauma patients still dying? Towards a systems hypothesis of trauma'. Frontiers in Physiology, 13 . [DOI]
The role of matrix metalloproteinase-9 and its inhibitor TIMP-1 in burn injury: a systematic review
2021
Sharma, Chinmay; Dobson, Geoffrey P.; Davenport, Lisa; Morris, Jodie L.; Letson, Hayley L. (2021) 'The role of matrix metalloproteinase-9 and its inhibitor TIMP-1 in burn injury: a systematic review'. International Journal of Burns and Trauma, 11 (4):275-288.
Morris, Jodie L.; Letson, Hayley L.; McEwen, Peter; Biros, Erik; Dlaska, Constantin; Hazratwala, Kaushik; Wilkinson, Matthew; Dobson, Geoffrey P. (2021) 'Comparison of intra‑articular administration of adenosine, lidocaine and magnesium solution and tranexamic acid for alleviating postoperative inflammation and joint fibrosis in an experimental model of knee arthroplasty'. Journal of Orthopaedic Surgery and Research, 16 . [DOI]
Morris, Jodie L.; Letson, Hayley L.; McEwen, Peter; Biros, Erik; Dlaska, Constantin; Hazratwala, Kaushik; Wilkinson, Matthew; Dobson, Geoffrey P. (2021) 'Intra-articular Adenosine, Lidocaine and Magnesium (ALM) solution decreases postoperative joint fibrosis in an experimental knee implant model'. Translational Medicine Communications, 6 . [DOI]
Morris, Jodie L.; Govan, Brenda L.; Rush, Catherine M.; Ketheesan, Natkunam (2021) 'Identification of defective early immune responses to Burkholderia pseudomallei infection in a diet-induced murine model of type 2 diabetes'. Microbes and Infection, 23 (4-5). [DOI]
Journal Publication
ResearchOnline@JCU
Dobson, Geoffrey P.; Biros, Erik; Letson, Hayley L.; Morris, Jodie L. (2021) 'Living in a hostile world: inflammation, new drug development, and coronavirus'. Frontiers in Immunology, 11 . [DOI]
Dobson, Geoffrey P.; Morris, Jodie L.; Biros, Erik; Davenport, Lisa M.; Letson, Hayley L. (2021) 'Major surgery leads to a proinflammatory phenotype: differential gene expression following a laparotomy'. Annals Of Medicine And Surgery, 71 . [DOI]
Dobson, Geoffrey P.; Morris, Jodie L.; Davenport, Lisa M.; Letson, Hayley L. (2020) 'Traumatic-induced coagulopathy as a systems failure: a new window into hemostasis'. Seminars in Thrombosis and Hemostasis, 46 (2):199-214. [DOI]
Journal Publication
ResearchOnline@JCU
Morris, Jodie L.; Letson, Hayley L.; Elliott, Lisa; Grant, Andrea L.; Wilkinson, Matthew; Hazratwala, Kaushik; McEwen, Peter (2019) 'Evaluation of bacteriophage as an adjunct therapy for treatment of peri-prosthetic joint infection caused by Staphylococcus aureus'. PLoS ONE, 14 (12). [DOI]
Conventional and specific-pathogen free rats respond differently to anesthesia and surgical trauma
2019
Letson, Hayley L.; Morris, Jodie; Biros, Erik; Dobson, Geoffrey P. (2019) 'Conventional and specific-pathogen free rats respond differently to anesthesia and surgical trauma'. Scientific Reports, 9 . [DOI]
Morris, Jodie L.; Letson, Hayley L.; Grant, Andrea; Wilkinson, Matthew; Hazratwala, Kaushik; McEwen, Peter (2019) 'Experimental model of peri-prosthetic infection of the knee caused by Staphylococcus aureus using biomaterials representative of modern TKA'. Biology Open, 8 . [DOI]
Morris, Jodie; Kelly, Natasha; Elliott, Lisa; Grant, Andrea; Wilkinson, Matthew; Hazratwala, Kaushik; McEwen, Peter (2019) 'Evaluation of bacteriophage anti-biofilm activity for potential control of orthopedic implant-related infections caused by Staphylococcus Aureus'. Surgical Infections, 20 (1):16-24. [DOI]
Journal Publication
ResearchOnline@JCU
Letson, Hayley Louise; Morris, Jodie Louise; Biros, Erik; Dobson, Geoffrey Phillip (2019) 'Adenosine, lidocaine, and Mg2+ fluid therapy leads to 72-hour survival after hemorrhagic shock'. Journal of Trauma and Acute Care Surgery, 87 (3):606-613. [DOI]
Journal Publication
ResearchOnline@JCU
McCutchan, Andrew; Dobson, Geoffrey P.; Stewart, Natalie; Letson, Hayley L.; Grant, Andrea L.; Jovanovic, Ivana-Aleksandra; Hazratwala, Kaushik; Wilkinson, Matthew; McEwen, Peter; Morris, Jodie (2019) 'Absence of cytotoxic and inflammatory effects following in vitro exposure of chondrogenically-differentiated human mesenchymal stem cells to adenosine, lidocaine and Mg2+ solution'. Journal of Experimental Orthopaedics, 6 . [DOI]
Morris, Jodie L.; Letson, Hayley L.; Gillman, Rhys; Hazratwala, Kaushik; Wilkinson, Matthew; McEwen, Peter; Dobson, Geoffrey P. (2019) 'The CNS theory of osteoarthritis: opportunities beyond the joint'. Seminars in Arthritis and Rheumatism, 49 (3):331-336. [DOI]
Journal Publication
ResearchOnline@JCU
Grant, Andrea L.; Letson, Hayley L.; Morris, Jodie L.; McEwen, Peter; Hazratwala, Kaushik; Wilkinson, Matthew; Dobson, Geoffrey P. (2018) 'Tranexamic acid is associated with selective increase in inflammatory markers following total knee arthroplasty (TKA): a pilot study'. Journal of Orthopaedic Surgery and Research, 13 . [DOI]
Dobson, G.P.; Letson, H.L.; Grant, A.; McEwen, P.; Hazratwala, K.; Wilkinson, M.; Morris, J.L. (2018) 'Defining the osteoarthritis patient: back to the future'. Osteoarthritis and Cartilage, 26 (8):1003-1007. [DOI]