The open field test for measuring locomotor activity and anxiety-like behavior

The open field test is used in studies of the neurobiological basis of anxiety and screening for novel drug targets and anxiolytic compounds. This test uses a camera to measure movement of the test animal in the peripheral and central zones of a 42 x 42 x 42 cm polyvinyl chloride box. This chapter describes a protocol for carrying out the open-field test for assessment of locomotion and anxiety-like behavior in mice.

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Pre-Clinical Models: techniques and protocols

1916

978-1-4939-8993-5

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