Establishing a rodent model of rheumatic heart disease to evaluate hookworm-derived frontline proteins NaAIP1 and AcFAR2 as therapeutic candidates

James Cook University
Suchandan Sikder
Role

Chief Investigator

Description

This project aims to establish a robust rodent model of rheumatic heart disease (RHD) to investigate pathological cardiac inflammation and provide a platform for therapeutic evaluation. Using this model, we will assess the efficacy and mechanisms of hookworm-derived immunomodulatory proteins as novel therapeutic candidates for RHD.

Date

01 Aug 2026 - 31 Jul 2027

Project Type

N/A

Keywords

N/A

Funding Body

James Cook University

Amount

10000

Project Team

N/A