Experimental Albizia versicolor poisoning in sheep and its successful treatment with pyridoxine hydrochloride

Journal Publication ResearchOnline@JCU
Gummow, Bruce;Bastianello, Stella S.;Labuschagne, Leoni;Erasmus, G.L.
Abstract

F!ve sheep developed severe nervous signs after being drenched with Albizia versicolor pod-material. Four of these sheep were treated with pyridoxine hydrochloride (a vitamin B6) when the symptoms of toxicity became life-threatening. All the treated sheep recovered dramatically and completely after treatment while the untreated one died 2 h after receiving pod-material. A therapeutic dose of 20-25 mg pyridoxine hydrochloride/kg body mass given twice with an 8 h interval is the recommended treatment regimen. The route of administration will depend on the severity of symptoms. Chemical pathology and post-mortem findings are discussed.

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Onderstepoort Journal of Veterinary Research

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59

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0030-2465

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8

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Onderstepoort Veterinary Institute

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