Immunomodulatory vaccines in the treatment of peanut allergy (Old ID 27579)

National Health and Medical Research Council (NHMRC)
Role

Principal Investigator

Description

Peanut allergy is the most common cause of food-induced anaphylactic reactions in Australia and is a major burden to our healthcare system. Current clinical practice advice dietary avoidance to prevent fatal anaphylactic responses. We propose the use of an immunomodulatory vaccine to re-write the immune response to peanut antigens, from an allergic to a tolerant phenotype. This study will provide novel insights into rational approaches for manipulating immune memory to food allergens.

Date

01 Jan 2021 - 31 Dec 2023

Project Type

GRANT

Keywords

Food Allergy;IgE Antibody;Cellular Immunology;Vaccine;Immunotherapy;Anaphylaxis

Funding Body

National Health and Medical Research Council (NHMRC)

Amount

33784.3

Project Team

N/A