Circulating human papillomavirus (HPV) DNA for surveillance of HPV-related oropharyngeal squamous cell carcinoma (HPV-OPSCC)
Townsville Hospital and Health Service
Role
Collaborator
Description
We hypothesize that cHPV-DNA-based post-treatment surveillance via capture-based NGS would have excellent negative predictive value (NPV) and positive predictive value (PPV) similar or superior to PCR-based testing in patients with HPV-OPSCC, leading to improvement in outcome prediction. We also hypothesize that cHPV-DNA-based surveillance is more cost-effective compared with standard routine clinical follow-up.
Date
01 Aug 2024 - 30 Jul 2026
Project Type
GRANT
Keywords
cancer;diagnostics;proteomics
Funding Body
Townsville Hospital and Health Service
Amount
49498
Project Team
Ulf Schmitz