Short and long-term effects of sham-controlled prefrontal EEG-neurofeedback training in healthy subjects

Engelbregt, H. J.;Keeser, D.;van Eijk, L.;Suiker, E. M.;Eichhorn, D.;Karch, S.;Deijen, J. B.;Pogarell, O.

Abstract

Objective: In this study we evaluated long-term effects of frontal beta EEG-neurofeedback training (E-NFT) on healthy subjects. We hypothesized that E-NFT can change frontal beta activity in the long-term and that changes in frontal beta EEG activity are accompanied by altered cognitive performance. Methods: 25 healthy subjects were included and randomly assigned to active or sham E-NFT. On average the subjects underwent 15 E-NFT training sessions with a training duration of 45 min. Resting-state EEG was recorded prior to E-NFT training (t1) and in a 3-year follow-up (t3). Results: Compared to sham E-NFT, which was used for the control group, real E-NFT increased beta activity in a predictable way. This increase was maintained over a period of three years post training. However, E-NFT did not result in significantly improved cognitive performance. Conclusion: Based on our results, we conclude that EEG-NFT can selectively modify EEG beta activity both in short and long-term. Significance: This is a sham controlled EEG neurofeedback study demonstrating long-term effects in resting state EEG.

Journal

Clinical Neurophysiology

Publication Name

Clinical Neurophysiology

Volume

127

ISBN/ISSN

1872-8952

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Publisher

Elsevier

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DOI

10.1016/j.clinph.2016.01.004