Influenza A(H5N1) viruses with A(H9N2) single gene (matrix or PB1) reassortment isolated from Cambodian live bird markets

Journal Publication ResearchOnline@JCU

Suttie, Annika;Karlsson, Erik A.;Deng, Yi-Mo;Horm, Srey Viseth;Yann, Sokhoun;Tok, Songha;Sorn, San;Holl, Davun;Tum, Sothyra;Hurt, Aeron C.;Greenhill, Andrew R.;Barr, Ian G.;Horwood, Paul F.;Dussart, Philippe

Paul Horwood

Abstract

Live bird market surveillance for avian influenza viruses in Cambodia in 2015 has led to the detection of two 7:1 reassortant influenza A(H5N1) clade 2.3.2.1c viruses. These reassortant strains, designated A/duck/Cambodia/Z564W35M1/2015 and A/chicken/Cambodia/Z850W49M1/2015, both contained a single gene (PB1 and matrix gene, respectively) from concurrently circulating A(H9N2) influenza viruses. All other viral genes from both isolates clustered with A(H5N1) clade 2.3.2.1 viruses. Continued and prolonged co-circulation of influenza A(H5N1) and A(H9N2) viruses in Cambodian live bird markets may present a risk for the emergence of novel influenza reassortant viruses with negative agricultural and/or public health implications.

Journal

Virology

Publication Name

Virology

Volume

523

ISBN/ISSN

1096-0341

Edition

N/A

Issue

N/A

Pages Count

Location

N/A

Publisher

Elsevier

Publisher Url

N/A

Publisher Location

N/A

Publish Date

N/A

Url

N/A

Date

N/A

EISSN

N/A

DOI

10.1016/j.virol.2018.07.028