A randomised controlled trial of intravenous paracetamol and oral paracetamol to control acute pain (Old ID 21779)

Collaborator

The objective of this project is to provide evidence that intravenous paracetamol produces superior analgesia than oral paracetamol in the ED setting. Secondary objectives include providing evidence that IV paracetamol produces good patient satisfaction, few side effects and reduced length of hospital stay. The trial is designed as a prospective double blind randomised controlled trial with two parallel groups. 50 patients will receive placebo oral intervention and a 1g intravenous paracetamol formulation. The other 50 patients will receive 1g oral paracetamol and IV normal saline. Patients will be requested to chart their pain prior to analgesia and then at 15 minute intervals for the first hour and half hourly for the following 3 hours. Side effects, length of ED stay and patient satisfaction will also be recorded to assess the secondary objectives.

01 Jan 2015 - 27 Oct 2016

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