Establishing a North Queensland Liver Tumour Library: New therapeutic approaches for advanced Hepatocellular Carcinoma

Supervisor

The treatment options for advanced stage HCC patients remain poor. We found that the inhibition of a heat shock protein (HSP) with a small molecule inhibitor can restrict HCC growth. Now we intend to use pre-clinical models to test whether the combination of HSP inhibition and current immune based therapies are better in reducing tumour load. This will be undertaken using advanced cell biology techniques and mouse models. This new therapy may be able to be adapted to patients and could lead to improving their choice of therapies and outcome.

10 Jun 2024 - 01 Jul 2025

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