Oxidative Stress Parameters as Biomarkers of Cardiovascular Disease towards the Development and Progression
Journal Publication ResearchOnline@JCUAbstract
Cardiovascular disease (CVD) remains the leading cause of death globally, with unhealthy lifestyles today greatly increasing the risk. Over the decades, scientific investigation has been carried out on reactive oxygen species (ROS) and their resultant oxidative stress based on their changes made on biological targets such as lipids, proteins, and DNA. Since the existing clinical studies with antioxidants failed to provide relevant findings on CVD prediction, the focus has shifted towards recognition of oxidised targets as biomarkers to predict prognosis and response to accurate treatment. The identification of redox markers could help clinicians in providing risk stratification for CVD events beyond the traditional prognostic and diagnostic targets. This review will focus on how oxidant-related parameters can be applied as biomarkers for CVD based on recent clinical evidence.
Journal
Antioxidants
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Volume
11
ISBN/ISSN
2076-3921
Edition
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Issue
6
Pages Count
13
Location
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Publisher
MDPI Switzerland
Publisher Url
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Publisher Location
N/A
Publish Date
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Url
N/A
Date
N/A
EISSN
N/A
DOI
10.3390/antiox11061175