A Metal-Containing NP Approach to Treat Methicillin-Resistant Staphylococcus aureus (MRSA): Prospects and Challenges

Journal Publication ResearchOnline@JCU
Yeo, Wendy Wai Yeng;Maran, Sathiya;Kong, Amanda Shen-Yee;Cheng, Wan-Hee;Lim, Swee-Hua Erin;Loh, Jian-Yan;Lai, Kok-Song
James Loh
Abstract

Methicillin-resistant Staphylococcus aureus (MRSA) is an important cause of pneumonia in humans, and it is associated with high morbidity and mortality rates, especially in immunocompromised patients. Its high rate of multidrug resistance led to an exploration of novel antimicrobials. Metal nanoparticles have shown potent antibacterial activity, thus instigating their application in MRSA. This review summarizes current insights of Metal-Containing NPs in treating MRSA. This review also provides an in-depth appraisal of opportunities and challenges in utilizing metal-NPs to treat MRSA.

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15

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1996-1944

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14

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MDPI Publishers

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DOI

10.3390/ma15175802