A Database for Chemical Proteomics: ChEBI

Other Publication ResearchOnline@JCU
de Matos, Paula;Adams, Nico;Hastings, Janna;Moreno, Pablo;Steinbeck, Christoph
Abstract

Chemical proteomics is concerned with the identification of protein targets interacting with small molecules. Hence, the availability of a high quality and free resource storing small molecules is essential for the future development of the field. The Chemical Entities of Biological Interest (ChEBI) database is one such database. The scope of ChEBI includes any constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer, etc., identifiable as a separately distinguishable entity. These entities in question are either products of nature or synthetic products used to intervene in the processes of living organisms. In addition, ChEBI contains a chemical ontology which relates the small molecules with each other thereby making it easier for users to discover data. The ontology also describes the biological roles that the small molecules are active in. The ChEBI database also provides a central reference point in which to access a variety of bioinformatics data points such as pathways and their biochemical reactions; expression data; protein sequence and structures.

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Publication Name

Chemical Proteomics

Volume

803

ISBN/ISSN

1064-3745

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Pages Count

24

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Publisher

Springer

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Publisher Location

New York, NY, USA

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DOI

10.1007/978-1-61779-364-6_19