Pathogen genomics in public health

Journal Publication ResearchOnline@JCU
Armstrong, Gregory L.;MacCannell, Duncan R.;Taylor, Jill;Carleton, Heather A.;Neuhaus, Elizabeth B.;Bradbury, Richard S.;Posey, James E.;Gwinn, Marta
Richard Bradbury
Abstract

Rapid advances in DNA sequencing technology (“next-generation sequencing”) have inspired optimism about the potential of human genomics for “precision medicine.” Meanwhile, pathogen genomics is already delivering “precision public health” through more effective investigations of outbreaks of foodborne illnesses, better-targeted tuberculosis control, and more timely and granular influenza surveillance to inform the selection of vaccine strains. In this article, we describe how public health agencies have been adopting pathogen genomics to improve their effectiveness in almost all domains of infectious disease. This momentum is likely to continue, given the ongoing development in sequencing and sequencing-related technologies.

Journal

New England Journal of Medicine

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Volume

381

ISBN/ISSN

1533-4406

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Issue

26

Pages Count

12

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Publisher

Massachusetts Medical Society

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EISSN

N/A

DOI

10.1056/NEJMsr1813907