More parasitic myositis cases in humans in Australia, and the definition of genetic markers for the causative agents as a basis for molecular diagnosis

Journal Publication ResearchOnline@JCU
Koehler, Anson V.;Spratt, David M.;Norton, Robert;Warren, Sanchia;McEwan, Belinda;Urkude, Ravindra;Murthy, Suresh;Robertson, Thomas;McCallum, Naomi;Parsonson, Fiona;Bradbury, Richard S.;Gasser, Robin B.
Abstract

Since 1998, there have been six reported human cases of myositis in Australia, attributable to infection with the nematode Haycocknema perplexum. However, an unequivocal diagnosis of H. perplexum infection and associated disease has been seriously compromised by a lack of molecular markers for this nematode. Here, we report new cases of disseminated myositis in two male patients from the states of Queensland and Tasmania in Australia, respectively; genetically characterize the causative agent from each case; and, also establish a PCR-based sequencing approach as a tool to support the diagnosis of future cases and to underpin epidemiological studies.

Journal

Infection, Genetics and Evolution

Publication Name

N/A

Volume

44

ISBN/ISSN

1567-7257

Edition

N/A

Issue

N/A

Pages Count

7

Location

N/A

Publisher

Elsevier

Publisher Url

N/A

Publisher Location

N/A

Publish Date

N/A

Url

N/A

Date

N/A

EISSN

N/A

DOI

10.1016/j.meegid.2016.06.026