Virome of Australia's most endangered parrot in captivity evidenced of harboring hitherto unknown viruses

Journal Publication ResearchOnline@JCU
Klukowski, Natalie;Eden, Paul;Uddin, Muhammad Jasim;Sarker, Subir
Abstract

The detection of emerging infectious diseases (EIDs) within endangered animal populations is increasing rapidly because of many factors, such as anthropogenic influences and climate change. Their impacts can be extensive and may further contribute to the processes risking the threat of extinction of these species. EIDs may be caused by a range of pathogens, including viruses, bacteria, parasites, and fungi. However, detection and diagnosis can be challenging with limited knowledge of existing pathogens in endangered wildlife. The critically endangered orange-bellied parrot (OBP, Neophema chrysogaster), with as few as 70 wild individuals, is a species at risk of extinctions, yet little research has been conducted into their existing viral diversity (virome). To determine the virome in a subset of the captive OBP population, this study characterized the fecal virome using a viral metagenomic approach. Analysis of the generated sequence data sets identified 11 viruses belonging to the families Adenoviridae, Circoviridae, Parvoviridae, and Picornaviridae. Strikingly, eight viruses were detected in the OBPs housed in Aviary 1 compared to only three viruses in OBPs housed at Aviary 2. In addition to detecting six novel viruses, this study also demonstrated ongoing infection with psittacine siadenovirus F. This study highlights the need to broaden this research to other populations of this species. Further virome characterization of co-habiting birds could also identify potential novel viruses and provide insight into their evolutionary relationship. These findings may contribute to strategic management and biosecurity plans for the conservation of endangered parrots.

Journal

Microbiology Spectrum

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Volume

12

ISBN/ISSN

2165-0497

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Issue

1

Pages Count

16

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Publisher

American Society for Microbiology

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DOI

10.1128/spectrum.03052-23