Characterisation of a novel aviadenovirus associated with disease in tawny frogmouths (Podargus strigoides)

Journal Publication ResearchOnline@JCU
Athukorala, Ajani;Lacasse, Claude;Curtiss, Jeffrey B.;Phalen, David N.;Sarker, Subir
Abstract

Aviadenoviruses are widespread in wild birds but rarely cause disease in nature. However, when naïve species are exposed to poultry or aviaries, aviadenoviruses can lead to disease outbreaks. This study characterised a novel aviadenovirus infection in a native Australian bird, the tawny frogmouth (Podargus strigoides) during an outbreak investigation. The identified complete genome of aviadenovirus, named tawny frogmouth aviadenovirus A (TwAviAdV-A) was 41,175 bp in length containing 52 putative genes. TwAviAdV-A exhibits the common aviadenovirus genomic organisation but with a notable monophyletic subclade in the phylogeny. The TwAviAdV-A virus was hepatotrophic and the six frogmouths presented to the wildlife hospitals in South Eastern Queensland most commonly exhibited regurgitation (in four frogmouths). Three were died or euthanized, two recovered, and one showed no signs. The detection of TwAviAdV-A in frogmouths coming into care re-emphasizes the need for strict biosecurity protocols in wildlife hospitals and care facilities.

Journal

Virology

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Volume

588

ISBN/ISSN

1096-0341

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Pages Count

10

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Publisher

Elsevier

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EISSN

N/A

DOI

10.1016/j.virol.2023.109904