A resurgence and re-emergence of diphtheria in Nigeria, 2023

Journal Contribution ResearchOnline@JCU
Adegboye, Oyelola A.;Alele, Faith O.;Pak, Anton;Castellanos, Maria E.;Abdullahi, Mohammed;Okeke, Malachy I.;Emeto, Theophilus I.;McBryde, Emma S.
Anton PakMaru Castellanos ReynosaIyke EmetoEmma McBryde
Abstract

[Extract] Diphtheria is a highly contagious vaccine-preventable bacterial infection caused by Corynebacterium diphtheriae that primarily infects the throat (pharynx and tonsils) and nose. The bacterium has an estimated basic reproduction number of 1.7–4.3. Although diphtheria is treatable if detected early, it can lead to severe complications such as respiratory failure, heart problems and even deaths (case-fatality ratio among untreated, never vaccinated cases 28.8–29.2%). It remains a health problem in low-resource countries, particularly where vaccination uptake and coverage are low and where sanitation conditions remain poor.

Journal

Therapeutic Advances in Infectious Disease

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10

ISBN/ISSN

2049-937X

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Pages Count

4

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Publisher

Sage

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N/A

DOI

10.1177/20499361231161936