A clinical approach to tubulopathies in children and young adults
Journal Publication ResearchOnline@JCUAbstract
Kidney tubules are responsible for the preservation of fluid, electrolyte and acid-base homeostasis via passive and active mechanisms. These physiological processes can be disrupted by inherited or acquired aetiologies. The net result is a tubulopathy. It is important to make a prompt and accurate diagnosis of tubulopathies in children and young adults. This allows timely and appropriate management, including disease-specific therapies, and avoids complications such as growth failure. Tubulopathies can present with a variety of non-specific clinical features which can be diagnostically challenging. In this review, we build from this common anatomical and physiological understanding to present a tangible appreciation of tubulopathies as they are likely to be clinically encountered among affected children and young adults.
Journal
Pediatric Nephrology
Publication Name
N/A
Volume
38
ISBN/ISSN
0931-041X
Edition
N/A
Issue
N/A
Pages Count
12
Location
N/A
Publisher
Springer-Verlag New York
Publisher Url
N/A
Publisher Location
N/A
Publish Date
N/A
Url
N/A
Date
N/A
EISSN
N/A
DOI
10.1007/s00467-022-05606-1