Editorial: Recent advances in the immunology of helminth infection – protection, pathogenesis and panaceas

Filbey, Kara J.;Finney, Constance A.M.;Giacomin, Paul R.;Siracusa, Mark C.

Abstract

[Extract] Helminths (parasitic worms) are a diverse group of organisms that utilize a wide range of species as their intermediate and definitive hosts. The nematodes consist of the whipworms, roundworms, hookworms and filarial worms, and these sit alongside the platyhelminth flatworms (or blood flukes) and tapeworms - all of which have species that cause serious disease in humans. Some species have free living stages, others rely on insect vectors for transmission, while some can reproduce to release live larval stages within their mammalian host. The diversity of infection route, larval migration within the host and the location of the adult parasite have major implications for the pathology and immune responses elicited by each species. Here, we briefly outline the contributions to the Research Topic Recent Advances in the Immunology of Helminth Infection – Protection, Pathogenesis and Panaceas.

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Frontiers in Immunology

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1664-3224

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Frontiers Research Foundation

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DOI

10.3389/fimmu.2021.663753