In reply to 'Interferon-gamma release assays have suboptimal sensitivity in both latent and active tuberculosis'
Journal Contribution ResearchOnline@JCUCastellanos, M.E.;Martinez, L.;Whalen, C.C.
Abstract
[Extract] We thank Goetzinger et al. for their interest and comments about our work.1 They raise a number of valid points about the suboptimal performance of interferon-gamma release assays (IGRAs) in the diagnosis of tuberculous infection in pediatric populations. The tuberculin skin test (TST) and IGRA tests have known limitations for the diagnosis of latent tuberculous infection (LTBI).2 We propose, as suggested by Goetzinger et al., that these tests should be interpreted in the full clinical context.
Journal
International Journal of Tuberculosis and Lung Disease
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N/A
Volume
23
ISBN/ISSN
1815-7920
Edition
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Issue
6
Pages Count
1
Location
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Publisher
International Union against Tuberculosis and Lung Disease
Publisher Url
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Publisher Location
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Publish Date
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Url
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Date
N/A
EISSN
N/A
DOI
10.5588/ijtld.18.0749