Two probable cases of infection with Treponema pallidum during the Neolithic period in Northern Vietnam (~2000- 1500B.C.)

Journal Publication ResearchOnline@JCU
Vlok, Melandri;Oxenham, Marc Fredrick;Domett, Kate;Tran Thi, Minh;Nguyen Thi Mai, Huong;Matsumura, Hirofumi;Trinh, Hiep Hoang;Higham, Tom;Higham, Charles;Nghia, Truonh Huu;Buckley, Hallie Ruth
Abstract

Skeletal evidence of two probable cases of treponematosis, caused by infection with the bacterium Treponema pallidum, from the northern Vietnamese early Neolithic site of Man Bac (1906–1523 cal B.C.) is described. The presence of nodes of subperiosteal new bone directly associated with superfcial focal cavitations in a young adult male and a seven- year- old child are strongly diagnostic for treponemal disease. Climatic and epidemiological contexts suggest yaws (Treponema pallidum pertenue) as the most likely causative treponeme. This evidence is the oldest discovered in the Asia- Pacific region and is the first well- established pre-Columbian example in this region in terms of diagnosis and secure dating. The coastal ecology, sedentary settlement, and high fertility at the site of Man Bac all provided a biosocial context conducive to the spread of treponemal disease among inhabitants of the site. Co- morbidity with scurvy in both individuals demonstrates that malnutrition during the agricultural transition may have exacerbated the expression of treponematosis in this community. Man Bac is a site of great regional importance owing to its role during the Neolithic transition of Mainland Southeast Asia. During this transition, approximately 4,000 years ago, farmers migrating from southern China into Southeast Asia influenced a number of changes in subsistence and demography and potentially introduced new infectious diseases such as treponematosis to indigenous forager communities. The findings presented here may encourage reevaluation of existing Southeast Asian skeletal samples and demonstrate the importance of using weighted diagnostic criteria for future reporting of treponematosis cases.

Journal

Bioarchaeology International

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4

ISBN/ISSN

2472-8357

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1

Pages Count

22

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University of Florida Press

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DOI

10.5744/bi.2020.1000