Genetic predisposition, humans

Other Publication ResearchOnline@JCU
Jordan, Margaret A.;Baxter, Alan G.
Margaret Jordan
Abstract

The translation from genetic knowledge to a molecular understanding of disease is contributing to the development of improved diagnostic and therapeutic products. Here, we briefly cover the localisation of autoimmune disease-associated loci and examine recent progress in molecular understanding of autoimmune disease that has been facilitated by these approaches. We concentrate primarily on progress in the genetics of type 1 diabetes, multiple sclerosis and systemic lupus erythematosus, and draw attention to parallels and contrasts between these diseases, other autoimmune diseases and other immune diseases.

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Publication Name

The Autoimmune Diseases

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ISBN/ISSN

978-0-12-812102-3

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Pages Count

36

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Publisher

Elsevier

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Publisher Location

Boston,MA, USA

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DOI

10.1016/B978-0-12-812102-3.00023-3