Protein-directed in situ synthesis of gold nanoparticles on reduced graphene oxide modified electrode for nonenzymatic glucose sensing

Journal Publication ResearchOnline@JCU
Liu, Yang;Dong, Yongqiang;Guo, Chun Xian;Cui, Zhiming;Zheng, Lianxi;Li, Chang Ming
Yang Liu
Abstract

A novel nonenzymatic glucose sensor was developed based on well-dispersed gold nanoparticles, which were in situ grown under direction of protein on a reduced graphene oxide modified electrode. This electrode exhibited high electrocatalytic activity towards glucose oxidation without use of any enzyme or mediator. In application for the amperometric detection of glucose, a wide linear range of 0.02-16.6mM, low detection limit of 5μM and good selectivity were obtained. The attractive analytical performances of the proposed glucose sensor, coupled with the facile preparation method, provide a promising electrochemical platform for the development of effective nonenzymatic sensors.

Journal

Electroanalysis

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Volume

24

ISBN/ISSN

1521-4109

Edition

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Issue

12

Pages Count

6

Location

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Publisher

Wiley

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Date

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EISSN

N/A

DOI

10.1002/elan.201200472