Clinical relevance of a p value: Does tranexamic acid save lives after trauma or postpartum hemorrhage?

Journal Contribution ResearchOnline@JCU
Dobson, Geoffrey P.;Doma, Kenji;Letson, Hayley L.
Hayley Letson
Abstract

[Extract] Tranexamic acid (TXA), an antifibrinolytic agent, has been widely publicized as saving lives after traumatic hemorrhage in the CRASH-2, MSATTERs, and PER-TRAX trials (2-5) and more recently after postpartum hemorrhage (PPH) in the World Maternal Antifibrinolytic (WOMAN) trial (6). Prophylactic administration of TXA is also increasingly used in major elective and emergency surgery to reduce excessive bleeding, transfusion requirements, and possible reexploration. (7)

Journal

Journal of Trauma and Acute Care Surgery

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N/A

Volume

84

ISBN/ISSN

2163-0763

Edition

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Issue

3

Pages Count

5

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Publisher

Lippincott, Williams & Wilkins

Publisher Url

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Publisher Location

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Publish Date

N/A

Url

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Date

N/A

EISSN

N/A

DOI

10.1097/TA.0000000000001779