Short report: surveillance and molecular characterization of group A rotaviruses in Goroka, Papua New Guinea

Journal Publication ResearchOnline@JCU
Horwood, Paul Francis;Luang-Suarkia, Dagwin;Bebes, Sauli;Boniface, Karen;Datta, Siddhartha Sankar;Siba, Peter Max;Kirkwood, Carl Dunn
Abstract

In this study, we investigated the molecular epidemiology of group A rotaviruses in cases of acute gastroenteritis in Goroka, Papua New Guinea. From April 2008 through November 2010, 813 diarrheal stool samples were collected from children < 5 years of age hospitalized with acute gastroenteritis. Rotavirus antigen was detected in 31.2% of samples using a commercial enzyme-linked immunosorbent assay. Genotyping revealed the presence of the globally circulating strains G1P[8] (50.0%), G3P[8] (23.0%), and G2P[4] (8.2%). The globally emerging strains G9 and G12 were detected in 1.2% and 6.1% of samples, respectively. Mixed infections were detected in a high proportion of samples (11.9%), with 9.0% and 3.7% of samples displaying multiple G and P genotypes, respectively.

Journal

American Journal of Tropical Medicine and Hygiene

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Volume

87

ISBN/ISSN

1476-1645

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Issue

6

Pages Count

4

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Publisher

American Society of Tropical Medicine and Hygiene

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DOI

10.4269/ajtmh.2012.12-0234