First human case of fatal halicephalobus gingivalis meningoencephalitis in Australia

Journal Publication ResearchOnline@JCU
Lim, Chuan Kok;Crawford, April;Moore, Casey V.;Gasser, Robin B.;Nelson, Renjy;Koehler, Anson V.;Bradbury, Richard S.;Speare, Rick;Dhatrak, Deepak;Weldhagen, Gerhard F.
Richard Bradbury
Abstract

Halicephalobus gingivalis (previously Micronema deletrix) is a free-living nematode known to cause opportunistic infections, mainly in horses. Human infections are very rare, but all cases described to date involved fatal meningoencephalitis. Here we report the first case of H. gingivalis infection in an Australian human patient, confirmed by nematode morphology and sequencing of ribosomal DNA. The implications of this case are discussed, particularly, the need to evaluate real-time PCR as a diagnostic tool.

Journal

Journal of Clinical Microbiology

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N/A

Volume

53

ISBN/ISSN

1098-660X

Edition

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Issue

5

Pages Count

7

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Publisher

American Society for Microbiology

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Date

N/A

EISSN

N/A

DOI

10.1128/JCM.00032-15