Serum IP-10 in the diagnosis of latent and active tuberculosis

Journal Contribution ResearchOnline@JCU
Clifford, Vanessa;Tebruegge, Marc;Zufferey, Christel;Germano, Susie;Denholm, Justin;Street, Alan;McBryde, Emma;Eisen, Damon;Curtis, Nigel
Emma McBryde
Abstract

We read with interest the recent article by Wergeland et al., reporting that serum interferon-gamma inducible protein 10 (IP-10) may be a useful biomarker for differentiating between active tuberculosis (TB) and latent TB infection (LTBI), as well as for monitoring the effectiveness of anti-tuberculous therapy.1 However, a key limitation of this study was the absence of a 'sick control' group of patients with respiratory tract infections. Prompted by this finding, we analysed data from our ongoing study investigating novel biomarkers of active and latent TB.

Journal

Journal of Infection

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Volume

71

ISBN/ISSN

1532-2742

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Issue

6

Pages Count

3

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Publisher

W.B. Saunders

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Publisher Location

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Publish Date

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Date

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EISSN

N/A

DOI

10.1016/j.jinf.2015.08.001