Avoiding Guillan‐Barré syndrome following swine origin pandemic H1N1 2009 influenza vaccination

Eisen, Damon P.;McBryde, Emma S.

Abstract

[Extract] To the Editor—In learning from history, the infectious diseases community needs to be cognizant of the consequences of swine influenza vaccination. In 1976, a considerable number of patients in the United States died of H1N1/NJ/76 vaccine–induced Guillan-Barré Syndrome (GBS). We were pleased to read the recent article by Evans et al that highlights this issue, and we wish to further explore the pathogenesis of this vaccine-related severe adverse effect. By doing so we wish to call on vaccine producers to concentrate their efforts on reassuring the medical community and therapeutic product regulators that current vaccines against pandemic H1N1 will be unlikely to induce GBS.

Journal

Journal of Infectious Diseases

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200

ISBN/ISSN

1537-6613

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Publisher

University of Chicago Press

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DOI

10.1086/644782