Hetisine-type diterpenoid alkaloids from the Bhutanese medicinal plant Aconitum orochryseum

Journal Publication ResearchOnline@JCU
Wangchuk, Phurpa;Bremner, John;Samosorn, Siritron
Abstract

Investigation of Aconitum orochryseum, a Bhutanese traditional medicine ("gSo-ba Rig-pa") plant locally known as "Bong-kar", resulted in the isolation of three new hetisine-type diterpenoid alkaloids, named orochrine (1), 2-O-acetylorochrine (2), and 2-O-acetyl-7α- hydroxyorochrine (3), together with the previously reported alkaloids atisinium chloride (4) and virescenine (5). The structures of the new alkaloids were elucidated by spectroscopic data analysis.

Journal

Journal of Natural Products

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Volume

70

ISBN/ISSN

1520-6025

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Issue

11

Pages Count

4

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Publisher

American Chemical Society

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DOI

10.1021/np070266k