A Maximum-Likelihood relatedness estimator allowing for negative relatedness values
Journal Publication ResearchOnline@JCUAbstract
Previously reported maximum-likelihood pairwise relatedness (r) estimator of Thompson and Milligan (M) was extended to allow for negative r estimates under the regression interpretation of r. This was achieved by establishing the equivalency of the likelihoods used in the kinship program and the likelihoods of Thompson. The new maximum-likelihood (ML) estimator was evaluated by Monte Carlo simulations. It was found that the new ML estimator became unbiased significantly faster compared to the original M estimator when the amount of genotype information was increased. The effects of allele frequency estimation errors on the new and existing relatedness estimators were also considered.
Journal
Molecular Ecology Resources
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N/A
Volume
8
ISBN/ISSN
1755-0998
Edition
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Issue
2
Pages Count
8
Location
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Publisher
Blackwell Publishing
Publisher Url
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Publisher Location
Oxford, United Kingdom
Publish Date
N/A
Url
N/A
Date
N/A
EISSN
N/A
DOI
10.1111/j.1471-8286.2007.01940.x