A rationally designed vaccine for tuberculosis (Old ID 26852)

National Health and Medical Research Council (NHMRC)
Andreas Kupz
Role

Principal Investigator

Description

Tuberculosis kills more people than any other infectious disease, and approximately one third of the world's population is latently infected with Mycobacterium tuberculosis. Reactivation of latent tuberculosis is associated with immunosuppressive conditions, most notably AIDS and type 2 diabetes. This project aims to investigate correlates of protection against tuberculosis in these immunosuppressive conditions by using innovative mouse models and human samples and to develop a new TB vaccine.

Date

01 Jan 2021 - 31 Dec 2025

Project Type

GRANT

Keywords

Mycobacterium tuberculosis;AIDS;Bcg;Vaccination;Type 2 Diabetes

Funding Body

National Health and Medical Research Council (NHMRC)

Amount

1371593

Project Team

Denise Doolan;Emma McBryde;Matt Field