Unravelling immune heterogeneity in mycobacteria-exposed children from north Queensland
Role
Co Investigator
Description
This project aims to understand immune responses to tuberculosis (TB) in Indigenous children from Far North Queensland, particularly how BCG vaccination impacts immunity. By analyzing blood samples pre- and post-BCG, this study will identify immune markers and mechanisms that predict TB protection. Through advanced multiomic analyses, we will assess immune cell function, cytokine profiles, and genetic factors influencing individual responses to TB infection and vaccination. The expected outcomes include a clearer understanding of TB immunity in this high-risk group, informing better TB control strategies and ultimately contributing to improved health outcomes for Indigenous populations in the region.
Date
29 Apr 2025 - 28 Apr 2026
Project Type
N/A
Keywords
Tuberculosis;Immune correlates of protection;BCG vaccination
Funding Body
Far North Queensland Hospital Foundation
Amount
5000
Project Team
Andreas Kupz;Emma McBryde