Artificial intelligence-guided detection of tumour peptides for immunotherapy against therap y-resistant cutaneous squamous cell carcinoma (CSCC)
Role
Chief Investigator
Description
North Queensland has the highest incidence of CSCC worldwide, which has a huge impact on the local population. With a high tumour mutational burden, CSCC is responsive to immunotherapy, however therapy-resistant CSCC presents a significant challenge. This project aims to detect and select tumour-specific peptides for immunotherapy in patients with therapy-resistant CSCC. The focus on tumour-specific peptides aims to ensure that these peptides are unique to tumour cells, thereby minimising the risk of triggering autoimmunity in treated patients. This innovative approach seeks to enhance the precision and safety of immunotherapies by targeting tumour-specific antigens.
Date
01 Jan 2025 - 31 Dec 2026
Project Type
GRANT
Keywords
N/A
Funding Body
Tropical Australian Academic Health Centre Limited
Amount
50000
Project Team
N/A