Exploring the Long-Term Effects of Probiotic Supplementation in Premature Infants (Old ID 27028)
Role
Chief Investigator
Description
Probiotic supplementation is now standard care for pre-term infants in the neonatal intensive care unit (NICU); significantly reducing the risk of Necrotising Enterocolitis (NEC) and mortality. What is not known is the long-term impact of this probiotic treatment on the developing infant gut microbiome. Evidence from a previous study shows positive effects, however, two important questions remain. 1. Microbes from probiotic supplementation appear to colonize the infant gut, cause positive modulation and reduce the incidence of disease, does this effect persist over the first year of life? 2. Should the criteria for probiotic supplementation be expanded to include all infants?
Date
19 Oct 2020 - 31 Oct 2021
Project Type
N/A
Keywords
Microbiome;Neonatal;NICU;Gut microbiome
Funding Body
Australian Institute of Medical Scientists
Amount
5000
Project Team
Donna Rudd