Interaction between parathyroid hormone, sclerostin and the wingless pathway in abdominal aortic aneurysm (Old ID 19349)

National Health and Medical Research Council (NHMRC)
Catherine Rush
Role

Chief Investigator

Description

Approximately 5% of men and 1% of women aged over 60 years develop weakening of the main abdominal artery. Currently the management of artery weakening is focused on surgery with no effective medications available. In this study we will assess the role of a novel pathway in artery weakening. Improved understanding of the mechanisms causing artery degeneration is crucial to target the development of better ways to treat this common problem.

Date

01 Jan 2012 - 31 Dec 2016

Project Type

N/A

Keywords

Abdominal aortic aneurysm;Pathogenesis;Therapy;Patient management;Peripheral vascular disease;Cardiovascular Diseases

Funding Body

National Health and Medical Research Council (NHMRC)

Amount

698300

Project Team

Reinhold Muller;Catherine Rush