The anti-inflammatory effects of Australian box jellyfish (Chironex fleckeri) venom peptides on the complete Freund's adjuvant-induced arthritis
Far North Queensland Hospital Foundation
Role
Principal Investigator
Description
The novel project aims to investigate the anti-inflammatory and therapeutic potential of proteins extracted from Chironex fleckeri (box jellyfish) venom in experimental arthritis using DBA/J1 mice. Collagen Type II-induced arthritis will be established in DBA/J1 mice, and after three weeks, the mice will be treated with 20 µg of venom proteins. The anti-arthritis effects will be evaluated through knee joint histology, arthritis clinical scoring, and inflammatory cytokine assays.
Date
N/A - 30 Nov 2023
Project Type
GRANT
Keywords
N/A
Funding Body
Far North Queensland Hospital Foundation
Amount
43630
Project Team
Jamie Seymour;Nagaraja Haleagrahara