The anti-inflammatory effects of Australian box jellyfish (Chironex fleckeri) venom peptides on the complete Freund's adjuvant-induced arthritis

Far North Queensland Hospital Foundation
Role

Principal Investigator

Description

The novel project aims to investigate the anti-inflammatory and therapeutic potential of proteins extracted from Chironex fleckeri (box jellyfish) venom in experimental arthritis using DBA/J1 mice. Collagen Type II-induced arthritis will be established in DBA/J1 mice, and after three weeks, the mice will be treated with 20 µg of venom proteins. The anti-arthritis effects will be evaluated through knee joint histology, arthritis clinical scoring, and inflammatory cytokine assays.

Date

N/A - 30 Nov 2023

Project Type

GRANT

Keywords

N/A

Funding Body

Far North Queensland Hospital Foundation

Amount

43630

Project Team

Jamie Seymour;Nagaraja Haleagrahara